Improved photostable FRET-competent biarsenical-tetracysteine probes based on fluorinated fluoresceins

We have developed fluoro-substituted versions of the biarsenical-tetracysteine label FlAsH, exhibiting significant improvements in important properties over the original fluorescein derivative. In complexes with tetracysteine targets, F2FlAsH exhibits 50 times improved photostability, lower pH sensi...

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Detalles Bibliográficos
Autores principales:	Spagnuolo, C.C., Vermeij, R.J., Jares-Erijman, E.A.
Formato:	JOUR
Materias:	arsenic derivative biotin cysteine derivative dye fluorescein absorption spectroscopy anisotropy article chemical structure complex formation fluorescence fluorescence resonance energy transfer fluorescence spectroscopy fluorination irradiation pH photochemistry Arsenicals Cysteine Drug Stability Fluoresceins Fluorescence Polarization Fluorescence Resonance Energy Transfer Hydrocarbons, Fluorinated Hydrogen-Ion Concentration Oligopeptides Photochemistry
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_00027863_v128_n37_p12040_Spagnuolo
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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