Discrimination of nitroxyl and nitric oxide by water-soluble Mn(III) porphyrins
The water-soluble manganese(III) meso-tetrakis (N-ethylpyridinium-2-yl) porphyrin (MnIIITEPyP) and manganese(III) meso-(tetrakis(4-sulfonato- phenyl)) porphyrinate (MnIIITPPS) are able to chemically distinguish between HNO and NO donors, reacting with the former in a fast, efficient, and selective m...
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todo:paper_00027863_v127_n13_p4680_Marti2023-10-03T13:53:40Z Discrimination of nitroxyl and nitric oxide by water-soluble Mn(III) porphyrins Martí, M.A. Bari, S.E. Estrin, D.A. Doctorovich, F. Aromatic compounds Catalysis Decomposition Manganese compounds Organic acids Organometallics Probability density function Reaction kinetics Toluene Catalytic decomposition Discrimination Donors Porphyrins manganese derivative manganese meso[tetrakis(4 sulfonatophenyl)porphyrinate] manganese mesotetrakis(n ethylpyridinium 2 yl)porphyrin nitric oxide oxygen porphyrin derivative reagent sodium trioxodinitrate toluene sulfohydroxamic acid unclassified drug water aeration anaerobic metabolism aqueous solution article catalysis chemical reaction kinetics complex formation density functional theory solubility Anaerobiosis Hydroxamic Acids Kinetics Manganese Metalloporphyrins Nitric Oxide Nitric Oxide Donors Nitrites Nitrogen Oxides Oxidation-Reduction Porphyrins Solubility Water The water-soluble manganese(III) meso-tetrakis (N-ethylpyridinium-2-yl) porphyrin (MnIIITEPyP) and manganese(III) meso-(tetrakis(4-sulfonato- phenyl)) porphyrinate (MnIIITPPS) are able to chemically distinguish between HNO and NO donors, reacting with the former in a fast, efficient, and selective manner with concomitant formation of the {MnNO}7 complex (kon(HNO) ≈ 105 M-1 s-1), while they are inert or react very slowly with NO donors. DFT calculations and kinetic data suggest that HNO trapping is operative at least in the case of Mn IIITPPS, while catalytic decomposition of the HNO donors (sodium trioxodinitrate and toluene sulfohydroxamic acid) seems to be the main pathway for MnIIITEPyP. In the presence of oxygen, the product Mn IITEPyP(NO) oxidizes back to MnIIITEPyP, making it possible to process large ratios of nitroxyl donor with small amounts of porphyrin. © 2005 American Chemical Society. Fil:Martí, M.A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Bari, S.E. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Estrin, D.A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Doctorovich, F. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00027863_v127_n13_p4680_Marti |
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Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Aromatic compounds Catalysis Decomposition Manganese compounds Organic acids Organometallics Probability density function Reaction kinetics Toluene Catalytic decomposition Discrimination Donors Porphyrins manganese derivative manganese meso[tetrakis(4 sulfonatophenyl)porphyrinate] manganese mesotetrakis(n ethylpyridinium 2 yl)porphyrin nitric oxide oxygen porphyrin derivative reagent sodium trioxodinitrate toluene sulfohydroxamic acid unclassified drug water aeration anaerobic metabolism aqueous solution article catalysis chemical reaction kinetics complex formation density functional theory solubility Anaerobiosis Hydroxamic Acids Kinetics Manganese Metalloporphyrins Nitric Oxide Nitric Oxide Donors Nitrites Nitrogen Oxides Oxidation-Reduction Porphyrins Solubility Water |
| spellingShingle |
Aromatic compounds Catalysis Decomposition Manganese compounds Organic acids Organometallics Probability density function Reaction kinetics Toluene Catalytic decomposition Discrimination Donors Porphyrins manganese derivative manganese meso[tetrakis(4 sulfonatophenyl)porphyrinate] manganese mesotetrakis(n ethylpyridinium 2 yl)porphyrin nitric oxide oxygen porphyrin derivative reagent sodium trioxodinitrate toluene sulfohydroxamic acid unclassified drug water aeration anaerobic metabolism aqueous solution article catalysis chemical reaction kinetics complex formation density functional theory solubility Anaerobiosis Hydroxamic Acids Kinetics Manganese Metalloporphyrins Nitric Oxide Nitric Oxide Donors Nitrites Nitrogen Oxides Oxidation-Reduction Porphyrins Solubility Water Martí, M.A. Bari, S.E. Estrin, D.A. Doctorovich, F. Discrimination of nitroxyl and nitric oxide by water-soluble Mn(III) porphyrins |
| topic_facet |
Aromatic compounds Catalysis Decomposition Manganese compounds Organic acids Organometallics Probability density function Reaction kinetics Toluene Catalytic decomposition Discrimination Donors Porphyrins manganese derivative manganese meso[tetrakis(4 sulfonatophenyl)porphyrinate] manganese mesotetrakis(n ethylpyridinium 2 yl)porphyrin nitric oxide oxygen porphyrin derivative reagent sodium trioxodinitrate toluene sulfohydroxamic acid unclassified drug water aeration anaerobic metabolism aqueous solution article catalysis chemical reaction kinetics complex formation density functional theory solubility Anaerobiosis Hydroxamic Acids Kinetics Manganese Metalloporphyrins Nitric Oxide Nitric Oxide Donors Nitrites Nitrogen Oxides Oxidation-Reduction Porphyrins Solubility Water |
| description |
The water-soluble manganese(III) meso-tetrakis (N-ethylpyridinium-2-yl) porphyrin (MnIIITEPyP) and manganese(III) meso-(tetrakis(4-sulfonato- phenyl)) porphyrinate (MnIIITPPS) are able to chemically distinguish between HNO and NO donors, reacting with the former in a fast, efficient, and selective manner with concomitant formation of the {MnNO}7 complex (kon(HNO) ≈ 105 M-1 s-1), while they are inert or react very slowly with NO donors. DFT calculations and kinetic data suggest that HNO trapping is operative at least in the case of Mn IIITPPS, while catalytic decomposition of the HNO donors (sodium trioxodinitrate and toluene sulfohydroxamic acid) seems to be the main pathway for MnIIITEPyP. In the presence of oxygen, the product Mn IITEPyP(NO) oxidizes back to MnIIITEPyP, making it possible to process large ratios of nitroxyl donor with small amounts of porphyrin. © 2005 American Chemical Society. |
| format |
JOUR |
| author |
Martí, M.A. Bari, S.E. Estrin, D.A. Doctorovich, F. |
| author_facet |
Martí, M.A. Bari, S.E. Estrin, D.A. Doctorovich, F. |
| author_sort |
Martí, M.A. |
| title |
Discrimination of nitroxyl and nitric oxide by water-soluble Mn(III) porphyrins |
| title_short |
Discrimination of nitroxyl and nitric oxide by water-soluble Mn(III) porphyrins |
| title_full |
Discrimination of nitroxyl and nitric oxide by water-soluble Mn(III) porphyrins |
| title_fullStr |
Discrimination of nitroxyl and nitric oxide by water-soluble Mn(III) porphyrins |
| title_full_unstemmed |
Discrimination of nitroxyl and nitric oxide by water-soluble Mn(III) porphyrins |
| title_sort |
discrimination of nitroxyl and nitric oxide by water-soluble mn(iii) porphyrins |
| url |
http://hdl.handle.net/20.500.12110/paper_00027863_v127_n13_p4680_Marti |
| work_keys_str_mv |
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| _version_ |
1782025580112248832 |