Genetic architecture of olfactory behavior in drosophila melanogaster: Differences and similarities across development
In the holometabolous insect Drosophila melanogaster, genetic, physiological and anatomical aspects of olfaction are well known in the adult stage, while larval stages olfactory behavior has received some attention it has been less studied than its adult counterpart. Most of these studies focus on o...
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todo:paper_00018244_v43_n4_p348_Lavagnino2023-10-03T13:52:11Z Genetic architecture of olfactory behavior in drosophila melanogaster: Differences and similarities across development Lavagnino, N.J. Arya, G.H. Korovaichuk, A. Fanara, J.J. Development Drosophila melanogaster Genetic architecture Olfactory behavior article controlled study Drosophila melanogaster dynamics female gene gene expression gene function gene insertion gene rearrangement genetic analysis genetic organization genetic similarity genetic underpinning genetic variability heredity larval stage nonhuman olfactory system ontogeny OR gene smelling animal gene gene expression profiling gene expression regulation genetics homozygote larva mutagenesis nucleotide sequence odor olfactory receptor physiology time Drosophila melanogaster Hexapoda Animals DNA Mutational Analysis Drosophila melanogaster Gene Expression Profiling Gene Expression Regulation, Developmental Genes, Insect Homozygote Larva Mutagenesis Olfactory Receptor Neurons Smell Time Factors In the holometabolous insect Drosophila melanogaster, genetic, physiological and anatomical aspects of olfaction are well known in the adult stage, while larval stages olfactory behavior has received some attention it has been less studied than its adult counterpart. Most of these studies focus on olfactory receptor (Or) genes that produce peripheral odor recognition. In this paper, through a loss-of-function screen using P-element inserted lines and also by means of expression analyses of larval olfaction candidate genes, we extended the uncovering of the genetic underpinnings of D. melanogaster larval olfactory behavior by demonstrating that larval olfactory behavior is, in addition to Or genes, orchestrated by numerous genes with diverse functions. Also, our results point out that the genetic architecture of olfactory behavior in D. melanogaster presents a dynamic and changing organization across environments and ontogeny. © 2013 Springer Science+Business Media New York. Fil:Lavagnino, N.J. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Fanara, J.J. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00018244_v43_n4_p348_Lavagnino |
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Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
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Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Development Drosophila melanogaster Genetic architecture Olfactory behavior article controlled study Drosophila melanogaster dynamics female gene gene expression gene function gene insertion gene rearrangement genetic analysis genetic organization genetic similarity genetic underpinning genetic variability heredity larval stage nonhuman olfactory system ontogeny OR gene smelling animal gene gene expression profiling gene expression regulation genetics homozygote larva mutagenesis nucleotide sequence odor olfactory receptor physiology time Drosophila melanogaster Hexapoda Animals DNA Mutational Analysis Drosophila melanogaster Gene Expression Profiling Gene Expression Regulation, Developmental Genes, Insect Homozygote Larva Mutagenesis Olfactory Receptor Neurons Smell Time Factors |
| spellingShingle |
Development Drosophila melanogaster Genetic architecture Olfactory behavior article controlled study Drosophila melanogaster dynamics female gene gene expression gene function gene insertion gene rearrangement genetic analysis genetic organization genetic similarity genetic underpinning genetic variability heredity larval stage nonhuman olfactory system ontogeny OR gene smelling animal gene gene expression profiling gene expression regulation genetics homozygote larva mutagenesis nucleotide sequence odor olfactory receptor physiology time Drosophila melanogaster Hexapoda Animals DNA Mutational Analysis Drosophila melanogaster Gene Expression Profiling Gene Expression Regulation, Developmental Genes, Insect Homozygote Larva Mutagenesis Olfactory Receptor Neurons Smell Time Factors Lavagnino, N.J. Arya, G.H. Korovaichuk, A. Fanara, J.J. Genetic architecture of olfactory behavior in drosophila melanogaster: Differences and similarities across development |
| topic_facet |
Development Drosophila melanogaster Genetic architecture Olfactory behavior article controlled study Drosophila melanogaster dynamics female gene gene expression gene function gene insertion gene rearrangement genetic analysis genetic organization genetic similarity genetic underpinning genetic variability heredity larval stage nonhuman olfactory system ontogeny OR gene smelling animal gene gene expression profiling gene expression regulation genetics homozygote larva mutagenesis nucleotide sequence odor olfactory receptor physiology time Drosophila melanogaster Hexapoda Animals DNA Mutational Analysis Drosophila melanogaster Gene Expression Profiling Gene Expression Regulation, Developmental Genes, Insect Homozygote Larva Mutagenesis Olfactory Receptor Neurons Smell Time Factors |
| description |
In the holometabolous insect Drosophila melanogaster, genetic, physiological and anatomical aspects of olfaction are well known in the adult stage, while larval stages olfactory behavior has received some attention it has been less studied than its adult counterpart. Most of these studies focus on olfactory receptor (Or) genes that produce peripheral odor recognition. In this paper, through a loss-of-function screen using P-element inserted lines and also by means of expression analyses of larval olfaction candidate genes, we extended the uncovering of the genetic underpinnings of D. melanogaster larval olfactory behavior by demonstrating that larval olfactory behavior is, in addition to Or genes, orchestrated by numerous genes with diverse functions. Also, our results point out that the genetic architecture of olfactory behavior in D. melanogaster presents a dynamic and changing organization across environments and ontogeny. © 2013 Springer Science+Business Media New York. |
| format |
JOUR |
| author |
Lavagnino, N.J. Arya, G.H. Korovaichuk, A. Fanara, J.J. |
| author_facet |
Lavagnino, N.J. Arya, G.H. Korovaichuk, A. Fanara, J.J. |
| author_sort |
Lavagnino, N.J. |
| title |
Genetic architecture of olfactory behavior in drosophila melanogaster: Differences and similarities across development |
| title_short |
Genetic architecture of olfactory behavior in drosophila melanogaster: Differences and similarities across development |
| title_full |
Genetic architecture of olfactory behavior in drosophila melanogaster: Differences and similarities across development |
| title_fullStr |
Genetic architecture of olfactory behavior in drosophila melanogaster: Differences and similarities across development |
| title_full_unstemmed |
Genetic architecture of olfactory behavior in drosophila melanogaster: Differences and similarities across development |
| title_sort |
genetic architecture of olfactory behavior in drosophila melanogaster: differences and similarities across development |
| url |
http://hdl.handle.net/20.500.12110/paper_00018244_v43_n4_p348_Lavagnino |
| work_keys_str_mv |
AT lavagninonj geneticarchitectureofolfactorybehaviorindrosophilamelanogasterdifferencesandsimilaritiesacrossdevelopment AT aryagh geneticarchitectureofolfactorybehaviorindrosophilamelanogasterdifferencesandsimilaritiesacrossdevelopment AT korovaichuka geneticarchitectureofolfactorybehaviorindrosophilamelanogasterdifferencesandsimilaritiesacrossdevelopment AT fanarajj geneticarchitectureofolfactorybehaviorindrosophilamelanogasterdifferencesandsimilaritiesacrossdevelopment |
| _version_ |
1782023863624794112 |