Brucella lumazine synthase elicits a mixed Th1-Th2 immune response and reduces infection in mice challenged with Brucella abortus 544 independently of the adjuvant formulation used

Mostrar todas las versiones(3)

The immunogenicity and protective efficacy of recombinant lumazine synthase from Brucella spp. (rBLS) administered with different adjuvants was evaluated in mice. Mice were immunized with rBLS in the absence or the presence of aluminum hydroxide gel (BLS-A1), monophosphoryl lipid A (BLS-MPA), or inc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Velikovsky, C.A., Goldbaum, F.A., Cassataro, J., Estein, S., Bowden, R.A., Bruno, L., Fossati, C.A., Giambartolomei, G.H.
Formato:	Artículo publishedVersion
Lenguaje:	Inglés
Publicado:	2003
Materias:	aluminum hydroxide Brucella vaccine Freund adjuvant gamma interferon immunoglobulin G immunoglobulin G antibody immunoglobulin G1 immunoglobulin G2 interleukin 10 interleukin 2 interleukin 4 lumazine lumazine synthase phosphoryl lipid A recombinant enzyme unclassified drug animal experiment animal model article Brucella abortus brucellosis controlled study cytokine production drug effect drug formulation female immune response immunization immunogenicity mouse nonhuman priority journal spleen cell Th1 cell Th2 cell Adjuvants, Immunologic Animals Antibodies, Bacterial Brucella Brucella Vaccine Brucellosis Female Lymphocyte Activation Mice Mice, Inbred BALB C Multienzyme Complexes Th1 Cells Th2 Cells Vaccines, Synthetic
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_00199567_v71_n10_p5750_Velikovsky
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

Ejemplares similares

Brucella lumazine synthase elicits a mixed Th1-Th2 immune response and reduces infection in mice challenged with Brucella abortus 544 independently of the adjuvant formulation used
por: Velikovsky, C.A., et al.

Brucella lumazine synthase elicits a mixed Th1-Th2 immune response and reduces infection in mice challenged with Brucella abortus 544 independently of the adjuvant formulation used
por: Velikovsky, C.A., et al.
Publicado: (2003)

Brucella lumazine synthase elicits a mixed Th1-Th2 immune response and reduces infection in mice challenged with Brucella abortus 544 independently of the adjuvant formulation used
Publicado: (2003)

PyNTTTTGT prototype oligonucleotide IMT504 is a potent adjuvant for the recombinant Hepatitis B vaccine that enhances the Th1 response
por: Elias, F., et al.

PyNTTTTGT prototype oligonucleotide IMT504 is a potent adjuvant for the recombinant Hepatitis B vaccine that enhances the Th1 response
por: Elías, Fernanda
Publicado: (2005)

Brucella abortus : tipificación molecular por MLVA en aislamientos locales, análisis in silico de sus lipoproteínas e implicancia de las lipoproteínas en virulencia
por: Hollender, Daiana
Publicado: (2015)

Brucella abortus : tipificación molecular por MLVA en aislamientos locales, análisis in silico de sus lipoproteínas e implicancia de las lipoproteínas en virulencia
por: Hollender, Daiana
Publicado: (2015)

Brucella abortus : tipificación molecular por MLVA en aislamientos locales, análisis in silico de sus lipoproteínas e implicancia de las lipoproteínas en virulencia
por: Hollender, Daiana
Publicado: (2015)

A mucin-like peptide from Fasciola hepatica instructs dendritic cells with parasite specific Th1-polarizing activity
por: Noya, V., et al.

A mucin-like peptide from Fasciola hepatica instructs dendritic cells with parasite specific Th1-polarizing activity
Publicado: (2017)

Cytokine Signaling/Transcription Factor Cross-Talk in T Cell Activation and Th1-Th2 Differentiation
por: Liberman, A.C., et al.

Molecular mechanisms and Th1/Th2 pathways in corticosteroid regulation of cytokine production
por: Kovalovsky, Damián, et al.
Publicado: (2000)

Molecular mechanisms and Th1/Th2 pathways in corticosteroid regulation of cytokine production
por: Kovalovsky, D., et al.

Diminished production of T helper 1 cytokines correlates with T cell unresponsiveness to Brucella cytoplasmic proteins in chronic human brucellosis
por: Giambartolomei, Guillermo H., et al.
Publicado: (2002)

Cytokine Signaling/Transcription Factor Cross-Talk in T Cell Activation and Th1-Th2 Differentiation
por: Liberman, Ana, et al.
Publicado: (2003)

B21 anti-breast Ca
por: Baldi, A.

Human Infection with M- Strain of Brucella canis
por: Wallach, Jorge C., et al.
Publicado: (2004)

Trypanosoma cruzi trans-sialidase prevents elicitation of Th1 cell response via interleukin 10 and downregulates Th1 effector cells
por: Díaz, P.R., et al.

InVet. 2011, 13(2): 53-60 ISSN 1514-6634 (impreso) MODELO MURINO EN...
por: Clausse, M., et al.
Publicado: (2011)

Trypanosoma cruzi trans-sialidase prevents elicitation of Th1 cell response via interleukin 10 and downregulates Th1 effector cells
por: Musikant, Alejandro Daniel, et al.
Publicado: (2015)

Oral administration of one dose of cholera toxin induces a systemic immune response prior to a mucosal immune response by a direct presentation in the spleen
Publicado: (1998)

Oral administration of one dose of cholera toxin induces a systemic immune response prior to a mucosal immune response by a direct presentation in the spleen
por: Benedetti, R., et al.

B21 anti-breast Ca
Publicado: (1997)

Dexamethasone counteracts the immunostimulatory effects of triiodothyronine (T3) on dendritic cells
por: Montesinos, M.M., et al.

Oligoclonal bands and antibody responses in Multiple Sclerosis
Publicado: (2002)

Oligoclonal bands and antibody responses in Multiple Sclerosis
por: Correale, J., et al.

The bone marrow as a site of antibody production after a mucosal immunization
Publicado: (1995)

The bone marrow as a site of antibody production after a mucosal immunization
por: Benedetti, R., et al.

Dexamethasone counteracts the immunostimulatory effects of triiodothyronine (T3) on dendritic cells
Publicado: (2012)

Sympathetic control of specific and non-specific immune response
Publicado: (1989)

Sympathetic control of specific and non-specific immune response
por: Sales, M.E., et al.

Electrochemotherapy of tumors as in situ vaccination boosted by immunogene electrotransfer
Publicado: (2015)

Electrochemotherapy of tumors as in situ vaccination boosted by immunogene electrotransfer
por: Sersa, G., et al.

Divergence in macromolecular assembly: X-ray crystallographic structure analysis of lumazine synthase from Brucella abortus
por: Braden, B.C., et al.

Structural, functional and immunological studies on a polymeric bacterial protein
por: Baldi, P.C., et al.

Negative inotropic activity of antilaminin IgG: participation of cholinergic mechanisms
Publicado: (1989)

Negative inotropic activity of antilaminin IgG: participation of cholinergic mechanisms
por: Bacman, S., et al.

Nitric oxide modulation of the immune response against cholera toxin-adjuvated ovalbumin administered by the intranasal route
Publicado: (2004)

Nitric oxide modulation of the immune response against cholera toxin-adjuvated ovalbumin administered by the intranasal route
por: Gamba, G., et al.

DNA immunization with the ribosomal P2β gene of Trypanosoma cruzi fails to induce pathogenic antibodies
por: Levitus, Gabriela Laura, et al.
Publicado: (2003)