Chemical modification of carrageenans and application of the modified products
Carrageenans are sulfated galactans notably conspicuous in red seaweeds. Their abundance in renewable sources combined with their already proven biological activities and rheological properties has drawn their attention at both industrial and lab levels. Their complex though basically repeating stru...
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2016
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| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_97816348_v_n_p189_Cosenza http://hdl.handle.net/20.500.12110/paper_97816348_v_n_p189_Cosenza |
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paper:paper_97816348_v_n_p189_Cosenza2023-06-08T16:38:35Z Chemical modification of carrageenans and application of the modified products Alkaline treatment Carrageenans Chemical modifications Grafting Sulfation Carrageenans are sulfated galactans notably conspicuous in red seaweeds. Their abundance in renewable sources combined with their already proven biological activities and rheological properties has drawn their attention at both industrial and lab levels. Their complex though basically repeating structure has made carrageenans an interesting target for chemical modifications. In this way, newly functionalized polysaccharides can be obtained with enhanced and/or altered properties, either biological or rheological, but still maintaining fundamental properties such as biocompatibility and biodegradability. This chapter will focus on the different chemical modifications performed up to date on carrageenans and how these modifications have affected the polysaccharide properties. The simplest and best-known modification is the so-called alkaline treatment, only possible in carrageenans carrying -D-galactose 6-sulfate units, as they convert into 3,6-anhydrogalactose in the polysaccharide, thus increasing their gelling properties. The increase or decrease of the negative charge (i.e., oversulfation, desulfation, oxidation of C-6, etc.) comprises another common group of reactions carried out on these polysaccharides that can affect both the physicochemical and biochemical properties. Other reactions such as cationizations, depolymerizations and increases of the hydrophobicity have also been performed on these polysaccharides and have provided large variations of the original properties. Furthermore, the carrageenans have been used as backbones for crosslinking reactions as well as grafting to other polymeric molecules. These new biomaterials are of interest in the biomedical area, as they can be used for drug delivery and tissue engineering, among other uses. © 2016 by Nova Science Publishers, Inc. All rights reserved. 2016 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_97816348_v_n_p189_Cosenza http://hdl.handle.net/20.500.12110/paper_97816348_v_n_p189_Cosenza |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Alkaline treatment Carrageenans Chemical modifications Grafting Sulfation |
| spellingShingle |
Alkaline treatment Carrageenans Chemical modifications Grafting Sulfation Chemical modification of carrageenans and application of the modified products |
| topic_facet |
Alkaline treatment Carrageenans Chemical modifications Grafting Sulfation |
| description |
Carrageenans are sulfated galactans notably conspicuous in red seaweeds. Their abundance in renewable sources combined with their already proven biological activities and rheological properties has drawn their attention at both industrial and lab levels. Their complex though basically repeating structure has made carrageenans an interesting target for chemical modifications. In this way, newly functionalized polysaccharides can be obtained with enhanced and/or altered properties, either biological or rheological, but still maintaining fundamental properties such as biocompatibility and biodegradability. This chapter will focus on the different chemical modifications performed up to date on carrageenans and how these modifications have affected the polysaccharide properties. The simplest and best-known modification is the so-called alkaline treatment, only possible in carrageenans carrying -D-galactose 6-sulfate units, as they convert into 3,6-anhydrogalactose in the polysaccharide, thus increasing their gelling properties. The increase or decrease of the negative charge (i.e., oversulfation, desulfation, oxidation of C-6, etc.) comprises another common group of reactions carried out on these polysaccharides that can affect both the physicochemical and biochemical properties. Other reactions such as cationizations, depolymerizations and increases of the hydrophobicity have also been performed on these polysaccharides and have provided large variations of the original properties. Furthermore, the carrageenans have been used as backbones for crosslinking reactions as well as grafting to other polymeric molecules. These new biomaterials are of interest in the biomedical area, as they can be used for drug delivery and tissue engineering, among other uses. © 2016 by Nova Science Publishers, Inc. All rights reserved. |
| title |
Chemical modification of carrageenans and application of the modified products |
| title_short |
Chemical modification of carrageenans and application of the modified products |
| title_full |
Chemical modification of carrageenans and application of the modified products |
| title_fullStr |
Chemical modification of carrageenans and application of the modified products |
| title_full_unstemmed |
Chemical modification of carrageenans and application of the modified products |
| title_sort |
chemical modification of carrageenans and application of the modified products |
| publishDate |
2016 |
| url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_97816348_v_n_p189_Cosenza http://hdl.handle.net/20.500.12110/paper_97816348_v_n_p189_Cosenza |
| _version_ |
1769175793162780672 |