Two identified looming detectors in the locust: Ubiquitous lateral connections among their inputs contribute to selective responses to looming objects

In locusts, two lobula giant movement detector neurons (LGMDs) act as looming object detectors. Their reproducible responses to looming and their ethological significance makes them models for single neuron computation. But there is no comprehensive picture of the neurons that connect directly to ea...

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Autor principal: Sztarker, Julieta
Publicado: 2016
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_20452322_v6_n_p_Rind
http://hdl.handle.net/20.500.12110/paper_20452322_v6_n_p_Rind
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Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
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spelling paper:paper_20452322_v6_n_p_Rind2023-06-08T16:33:27Z Two identified looming detectors in the locust: Ubiquitous lateral connections among their inputs contribute to selective responses to looming objects Sztarker, Julieta In locusts, two lobula giant movement detector neurons (LGMDs) act as looming object detectors. Their reproducible responses to looming and their ethological significance makes them models for single neuron computation. But there is no comprehensive picture of the neurons that connect directly to each LGMD. We used high-through-put serial block-face scanning-electron-microscopy to reconstruct the network of input-synapses onto the LGMDs over spatial scales ranging from single synapses and small circuits, up to dendritic branches and total excitatory input. Reconstructions reveal that many trans-medullary-afferents (TmAs) connect the eye with each LGMD, one TmA per facet per LGMD. But when a TmA synapses with an LGMD it also connects laterally with another TmA. These inter-TmA synapses are always reciprocal. Total excitatory input to the LGMD 1 and 2 comes from 131,000 and 186,000 synapses reaching densities of 3.1 and 2.6 synapses per μm 2 respectively. We explored the computational consequences of reciprocal synapses between each TmA and 6 others from neighbouring columns. Since any lateral interactions between LGMD inputs have always been inhibitory we may assume these reciprocal lateral connections are most likely inhibitory. Such reciprocal inhibitory synapses increased the LGMD's selectivity for looming over passing objects, particularly at the beginning of object approach. © The Author(s) 2016. Fil:Sztarker, J. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 2016 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_20452322_v6_n_p_Rind http://hdl.handle.net/20.500.12110/paper_20452322_v6_n_p_Rind
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
description In locusts, two lobula giant movement detector neurons (LGMDs) act as looming object detectors. Their reproducible responses to looming and their ethological significance makes them models for single neuron computation. But there is no comprehensive picture of the neurons that connect directly to each LGMD. We used high-through-put serial block-face scanning-electron-microscopy to reconstruct the network of input-synapses onto the LGMDs over spatial scales ranging from single synapses and small circuits, up to dendritic branches and total excitatory input. Reconstructions reveal that many trans-medullary-afferents (TmAs) connect the eye with each LGMD, one TmA per facet per LGMD. But when a TmA synapses with an LGMD it also connects laterally with another TmA. These inter-TmA synapses are always reciprocal. Total excitatory input to the LGMD 1 and 2 comes from 131,000 and 186,000 synapses reaching densities of 3.1 and 2.6 synapses per μm 2 respectively. We explored the computational consequences of reciprocal synapses between each TmA and 6 others from neighbouring columns. Since any lateral interactions between LGMD inputs have always been inhibitory we may assume these reciprocal lateral connections are most likely inhibitory. Such reciprocal inhibitory synapses increased the LGMD's selectivity for looming over passing objects, particularly at the beginning of object approach. © The Author(s) 2016.
author Sztarker, Julieta
spellingShingle Sztarker, Julieta
Two identified looming detectors in the locust: Ubiquitous lateral connections among their inputs contribute to selective responses to looming objects
author_facet Sztarker, Julieta
author_sort Sztarker, Julieta
title Two identified looming detectors in the locust: Ubiquitous lateral connections among their inputs contribute to selective responses to looming objects
title_short Two identified looming detectors in the locust: Ubiquitous lateral connections among their inputs contribute to selective responses to looming objects
title_full Two identified looming detectors in the locust: Ubiquitous lateral connections among their inputs contribute to selective responses to looming objects
title_fullStr Two identified looming detectors in the locust: Ubiquitous lateral connections among their inputs contribute to selective responses to looming objects
title_full_unstemmed Two identified looming detectors in the locust: Ubiquitous lateral connections among their inputs contribute to selective responses to looming objects
title_sort two identified looming detectors in the locust: ubiquitous lateral connections among their inputs contribute to selective responses to looming objects
publishDate 2016
url https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_20452322_v6_n_p_Rind
http://hdl.handle.net/20.500.12110/paper_20452322_v6_n_p_Rind
work_keys_str_mv AT sztarkerjulieta twoidentifiedloomingdetectorsinthelocustubiquitouslateralconnectionsamongtheirinputscontributetoselectiveresponsestoloomingobjects
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