Survey of argentinean human plasma for ochratoxin a

The presence of ochratoxin A (OTA) in human blood has been reported for many countries, especially in Europe. However, so far no report exists concerning such a presence in Argentina. The aim of this study was to assess OTA concentration in human plasma in two different areas of Buenos Aires provinc...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Motta, Estela Leonor, Resnik, Silvia Liliana
Publicado:	2008
Materias:	Exposure Human plasma Mycotoxin Ochratoxin ochratoxin ester derivative adult antibody affinity Argentina article blood donor blood sampling controlled study female food contamination health survey high performance liquid chromatography human male priority journal solid phase extraction South and Central America blood analysis immunoaffinity chromatography major clinical study Adult Agriculture Chromatography, Liquid Female Food Contamination Humans Male Ochratoxins Statistics as Topic
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_19440049_v25_n5_p635_Pacin http://hdl.handle.net/20.500.12110/paper_19440049_v25_n5_p635_Pacin
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	paper:paper_19440049_v25_n5_p635_Pacin
record_format	dspace
spelling	paper:paper_19440049_v25_n5_p635_Pacin2023-06-08T16:32:23Z Survey of argentinean human plasma for ochratoxin a Motta, Estela Leonor Resnik, Silvia Liliana Exposure Human plasma Mycotoxin Ochratoxin ochratoxin ester derivative ochratoxin adult antibody affinity Argentina article blood donor blood sampling controlled study female food contamination health survey high performance liquid chromatography human male priority journal solid phase extraction South and Central America blood analysis immunoaffinity chromatography major clinical study Adult Agriculture Argentina Chromatography, Liquid Female Food Contamination Humans Male Ochratoxins Statistics as Topic The presence of ochratoxin A (OTA) in human blood has been reported for many countries, especially in Europe. However, so far no report exists concerning such a presence in Argentina. The aim of this study was to assess OTA concentration in human plasma in two different areas of Buenos Aires province. OTA was determined by high-performance liquid chromatography (HPLC) in 199 plasma samples from blood donors in Mar del Plata and 236 from General Rodríguez. Solid-phase extraction with Bakerbond® C-18 cartridge and a final purification with Ochraprep® immunoaffinity columns was employed. The limit of quantification of ochratoxin A was 0.019ngml−1 and the confirmation of OTA was by formation of ochratoxin A methyl ester. The results showed that 63.8% of human plasma samples from Mar del Plata and 62.3% from General Rodríguez were positive for OTA, with Winsorized means of 0.15 and 0.43ngml−1, respectively. It is important to continue the research to detect the foods responsible of the presence of OTA in plasma. © 2008 Taylor & Francis Group, LLC. Fil:Motta, E. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Resnik, S.L. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 2008 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_19440049_v25_n5_p635_Pacin http://hdl.handle.net/20.500.12110/paper_19440049_v25_n5_p635_Pacin
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	Exposure Human plasma Mycotoxin Ochratoxin ochratoxin ester derivative ochratoxin adult antibody affinity Argentina article blood donor blood sampling controlled study female food contamination health survey high performance liquid chromatography human male priority journal solid phase extraction South and Central America blood analysis immunoaffinity chromatography major clinical study Adult Agriculture Argentina Chromatography, Liquid Female Food Contamination Humans Male Ochratoxins Statistics as Topic
spellingShingle	Exposure Human plasma Mycotoxin Ochratoxin ochratoxin ester derivative ochratoxin adult antibody affinity Argentina article blood donor blood sampling controlled study female food contamination health survey high performance liquid chromatography human male priority journal solid phase extraction South and Central America blood analysis immunoaffinity chromatography major clinical study Adult Agriculture Argentina Chromatography, Liquid Female Food Contamination Humans Male Ochratoxins Statistics as Topic Motta, Estela Leonor Resnik, Silvia Liliana Survey of argentinean human plasma for ochratoxin a
topic_facet	Exposure Human plasma Mycotoxin Ochratoxin ochratoxin ester derivative ochratoxin adult antibody affinity Argentina article blood donor blood sampling controlled study female food contamination health survey high performance liquid chromatography human male priority journal solid phase extraction South and Central America blood analysis immunoaffinity chromatography major clinical study Adult Agriculture Argentina Chromatography, Liquid Female Food Contamination Humans Male Ochratoxins Statistics as Topic
description	The presence of ochratoxin A (OTA) in human blood has been reported for many countries, especially in Europe. However, so far no report exists concerning such a presence in Argentina. The aim of this study was to assess OTA concentration in human plasma in two different areas of Buenos Aires province. OTA was determined by high-performance liquid chromatography (HPLC) in 199 plasma samples from blood donors in Mar del Plata and 236 from General Rodríguez. Solid-phase extraction with Bakerbond® C-18 cartridge and a final purification with Ochraprep® immunoaffinity columns was employed. The limit of quantification of ochratoxin A was 0.019ngml−1 and the confirmation of OTA was by formation of ochratoxin A methyl ester. The results showed that 63.8% of human plasma samples from Mar del Plata and 62.3% from General Rodríguez were positive for OTA, with Winsorized means of 0.15 and 0.43ngml−1, respectively. It is important to continue the research to detect the foods responsible of the presence of OTA in plasma. © 2008 Taylor & Francis Group, LLC.
author	Motta, Estela Leonor Resnik, Silvia Liliana
author_facet	Motta, Estela Leonor Resnik, Silvia Liliana
author_sort	Motta, Estela Leonor
title	Survey of argentinean human plasma for ochratoxin a
title_short	Survey of argentinean human plasma for ochratoxin a
title_full	Survey of argentinean human plasma for ochratoxin a
title_fullStr	Survey of argentinean human plasma for ochratoxin a
title_full_unstemmed	Survey of argentinean human plasma for ochratoxin a
title_sort	survey of argentinean human plasma for ochratoxin a
publishDate	2008
url	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_19440049_v25_n5_p635_Pacin http://hdl.handle.net/20.500.12110/paper_19440049_v25_n5_p635_Pacin
work_keys_str_mv	AT mottaestelaleonor surveyofargentineanhumanplasmaforochratoxina AT resniksilvialiliana surveyofargentineanhumanplasmaforochratoxina
_version_	1768546695763722240

Survey of argentinean human plasma for ochratoxin a

Ejemplares similares