Retroviral-like features in the monomer of the major satellite DNA from the south american rodents of the genus ctenomys
It is well known that uninfected mammalian cells contain DNA sequences which are closely related to retroviral genomic segments. However, these sequences seldom (if ever) have been found associated to highly repetitive (satellite) DNA. RPCS is a 348 bp monomer of a major satellite DNA from the South...
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1993
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| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_19401744_v3_n6_p379_Rossi http://hdl.handle.net/20.500.12110/paper_19401744_v3_n6_p379_Rossi |
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paper:paper_19401744_v3_n6_p379_Rossi2023-06-08T16:32:19Z Retroviral-like features in the monomer of the major satellite DNA from the south american rodents of the genus ctenomys Rossi, Maria Susana Pesce, Carlos Gustavo Kornblihtt, Alberto Rodolfo Caviomorph rodents Retroviral LTRs Satellite DNA CCAAT enhancer binding protein CCAAT Enhancer Binding Proteins DNA binding protein DNA Binding Proteins nuclear protein satellite DNA transcription factor transcription factor nuclear factor 1 animal article binding site genetics metabolism molecular genetics nucleotide sequence Retrovirus rodent TATA box Animal Base Sequence Binding Sites CCAAT-Enhancer-Binding Proteins DNA, Satellite DNA-Binding Proteins Molecular Sequence Data Nuclear Proteins Retroviridae Rodentia TATA Box Transcription Factors It is well known that uninfected mammalian cells contain DNA sequences which are closely related to retroviral genomic segments. However, these sequences seldom (if ever) have been found associated to highly repetitive (satellite) DNA. RPCS is a 348 bp monomer of a major satellite DNA from the South American rodents of the genus Ctenomys. It was found that RPCS contains several elements which are typical of the V) region of retroviral LTRs. These elements are: a) a polypurine tract; b) two enhancer core sequences; c) two NF1 binding sites; d) two C/EBP binding sites; e) two CCAAT-motifs; f) a TATA box, and g) two putative polyadenylation motifs. Furthermore, the relative positions of these elements are as in the U, retroviral regions. © 1993 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted. Fil:Rossi, M.S. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Pesce, C.G. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Kornblihtt, A.R. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 1993 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_19401744_v3_n6_p379_Rossi http://hdl.handle.net/20.500.12110/paper_19401744_v3_n6_p379_Rossi |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Caviomorph rodents Retroviral LTRs Satellite DNA CCAAT enhancer binding protein CCAAT Enhancer Binding Proteins DNA binding protein DNA Binding Proteins nuclear protein satellite DNA transcription factor transcription factor nuclear factor 1 animal article binding site genetics metabolism molecular genetics nucleotide sequence Retrovirus rodent TATA box Animal Base Sequence Binding Sites CCAAT-Enhancer-Binding Proteins DNA, Satellite DNA-Binding Proteins Molecular Sequence Data Nuclear Proteins Retroviridae Rodentia TATA Box Transcription Factors |
| spellingShingle |
Caviomorph rodents Retroviral LTRs Satellite DNA CCAAT enhancer binding protein CCAAT Enhancer Binding Proteins DNA binding protein DNA Binding Proteins nuclear protein satellite DNA transcription factor transcription factor nuclear factor 1 animal article binding site genetics metabolism molecular genetics nucleotide sequence Retrovirus rodent TATA box Animal Base Sequence Binding Sites CCAAT-Enhancer-Binding Proteins DNA, Satellite DNA-Binding Proteins Molecular Sequence Data Nuclear Proteins Retroviridae Rodentia TATA Box Transcription Factors Rossi, Maria Susana Pesce, Carlos Gustavo Kornblihtt, Alberto Rodolfo Retroviral-like features in the monomer of the major satellite DNA from the south american rodents of the genus ctenomys |
| topic_facet |
Caviomorph rodents Retroviral LTRs Satellite DNA CCAAT enhancer binding protein CCAAT Enhancer Binding Proteins DNA binding protein DNA Binding Proteins nuclear protein satellite DNA transcription factor transcription factor nuclear factor 1 animal article binding site genetics metabolism molecular genetics nucleotide sequence Retrovirus rodent TATA box Animal Base Sequence Binding Sites CCAAT-Enhancer-Binding Proteins DNA, Satellite DNA-Binding Proteins Molecular Sequence Data Nuclear Proteins Retroviridae Rodentia TATA Box Transcription Factors |
| description |
It is well known that uninfected mammalian cells contain DNA sequences which are closely related to retroviral genomic segments. However, these sequences seldom (if ever) have been found associated to highly repetitive (satellite) DNA. RPCS is a 348 bp monomer of a major satellite DNA from the South American rodents of the genus Ctenomys. It was found that RPCS contains several elements which are typical of the V) region of retroviral LTRs. These elements are: a) a polypurine tract; b) two enhancer core sequences; c) two NF1 binding sites; d) two C/EBP binding sites; e) two CCAAT-motifs; f) a TATA box, and g) two putative polyadenylation motifs. Furthermore, the relative positions of these elements are as in the U, retroviral regions. © 1993 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted. |
| author |
Rossi, Maria Susana Pesce, Carlos Gustavo Kornblihtt, Alberto Rodolfo |
| author_facet |
Rossi, Maria Susana Pesce, Carlos Gustavo Kornblihtt, Alberto Rodolfo |
| author_sort |
Rossi, Maria Susana |
| title |
Retroviral-like features in the monomer of the major satellite DNA from the south american rodents of the genus ctenomys |
| title_short |
Retroviral-like features in the monomer of the major satellite DNA from the south american rodents of the genus ctenomys |
| title_full |
Retroviral-like features in the monomer of the major satellite DNA from the south american rodents of the genus ctenomys |
| title_fullStr |
Retroviral-like features in the monomer of the major satellite DNA from the south american rodents of the genus ctenomys |
| title_full_unstemmed |
Retroviral-like features in the monomer of the major satellite DNA from the south american rodents of the genus ctenomys |
| title_sort |
retroviral-like features in the monomer of the major satellite dna from the south american rodents of the genus ctenomys |
| publishDate |
1993 |
| url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_19401744_v3_n6_p379_Rossi http://hdl.handle.net/20.500.12110/paper_19401744_v3_n6_p379_Rossi |
| work_keys_str_mv |
AT rossimariasusana retrovirallikefeaturesinthemonomerofthemajorsatellitednafromthesouthamericanrodentsofthegenusctenomys AT pescecarlosgustavo retrovirallikefeaturesinthemonomerofthemajorsatellitednafromthesouthamericanrodentsofthegenusctenomys AT kornblihttalbertorodolfo retrovirallikefeaturesinthemonomerofthemajorsatellitednafromthesouthamericanrodentsofthegenusctenomys |
| _version_ |
1768543580958228480 |