Electrolytic ablation dose planning methodology

Electrolytic ablation (EA), a medical treatment increasingly used in solid tumor ablation, consists in the passage of a low direct electric current through two or more electrodes inserted in the tissue thus inducing pH fronts that destroys the tumor. The combined use of EA with a recently introduced...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado: 2016
Materias:
Electrochemical treatment
Electrolytic ablation
In silico model
In vitro model
pH front tracking
Tumors
Ablation
Electric fields
Electrodes
Environmental technology
Direct electric currents
Electrochemical treatments
Front tracking
In-silico models
In-vitro models
Medical treatment
Minimally invasive
Tissue ablations
Tissue
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_16800737_v53_n_p101_Lujan
http://hdl.handle.net/20.500.12110/paper_16800737_v53_n_p101_Lujan
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
id paper:paper_16800737_v53_n_p101_Lujan
record_format dspace
spelling paper:paper_16800737_v53_n_p101_Lujan2023-06-08T16:26:38Z Electrolytic ablation dose planning methodology Electrochemical treatment Electrolytic ablation In silico model In vitro model pH front tracking Tumors Ablation Electric fields Electrodes Environmental technology Tumors Direct electric currents Electrochemical treatments Front tracking In-silico models In-vitro models Medical treatment Minimally invasive Tissue ablations Tissue Electrolytic ablation (EA), a medical treatment increasingly used in solid tumor ablation, consists in the passage of a low direct electric current through two or more electrodes inserted in the tissue thus inducing pH fronts that destroys the tumor. The combined use of EA with a recently introduced one-probe two electrode device (OPTED) results in a minimally invasive tissue ablation technique. Despite its success related to low cost and minimum side effects, EA has drawbacks such as the difficulty in determining the current and time needed to assure total tumor ablation while avoiding healthy tissue intrusion. Here we introduce a realistic dose planning methodology in terms of the coulomb dosage administered and the associated pH tracking, that predicts an optimal EA/OPTED protocol treatment for a given tumor size, that is, the current and exposition time necessary to succeed in eliminating all the tumor mass while minimizing healthy tissue damage. © Springer Science+Business Media Singapore 2016. 2016 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_16800737_v53_n_p101_Lujan http://hdl.handle.net/20.500.12110/paper_16800737_v53_n_p101_Lujan
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic Electrochemical treatment
Electrolytic ablation
In silico model
In vitro model
pH front tracking
Tumors
Ablation
Electric fields
Electrodes
Environmental technology
Tumors
Direct electric currents
Electrochemical treatments
Front tracking
In-silico models
In-vitro models
Medical treatment
Minimally invasive
Tissue ablations
Tissue
spellingShingle Electrochemical treatment
Electrolytic ablation
In silico model
In vitro model
pH front tracking
Tumors
Ablation
Electric fields
Electrodes
Environmental technology
Tumors
Direct electric currents
Electrochemical treatments
Front tracking
In-silico models
In-vitro models
Medical treatment
Minimally invasive
Tissue ablations
Tissue
Electrolytic ablation dose planning methodology
topic_facet Electrochemical treatment
Electrolytic ablation
In silico model
In vitro model
pH front tracking
Tumors
Ablation
Electric fields
Electrodes
Environmental technology
Tumors
Direct electric currents
Electrochemical treatments
Front tracking
In-silico models
In-vitro models
Medical treatment
Minimally invasive
Tissue ablations
Tissue
description Electrolytic ablation (EA), a medical treatment increasingly used in solid tumor ablation, consists in the passage of a low direct electric current through two or more electrodes inserted in the tissue thus inducing pH fronts that destroys the tumor. The combined use of EA with a recently introduced one-probe two electrode device (OPTED) results in a minimally invasive tissue ablation technique. Despite its success related to low cost and minimum side effects, EA has drawbacks such as the difficulty in determining the current and time needed to assure total tumor ablation while avoiding healthy tissue intrusion. Here we introduce a realistic dose planning methodology in terms of the coulomb dosage administered and the associated pH tracking, that predicts an optimal EA/OPTED protocol treatment for a given tumor size, that is, the current and exposition time necessary to succeed in eliminating all the tumor mass while minimizing healthy tissue damage. © Springer Science+Business Media Singapore 2016.
title Electrolytic ablation dose planning methodology
title_short Electrolytic ablation dose planning methodology
title_full Electrolytic ablation dose planning methodology
title_fullStr Electrolytic ablation dose planning methodology
title_full_unstemmed Electrolytic ablation dose planning methodology
title_sort electrolytic ablation dose planning methodology
publishDate 2016
url https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_16800737_v53_n_p101_Lujan
http://hdl.handle.net/20.500.12110/paper_16800737_v53_n_p101_Lujan
_version_ 1768544466168184832

Ejemplares similares