Micro/nanostructured hyaluronic acid matrices with tuned swelling and drug release properties

Hyaluronic acid (HA) hydrogels were structured in the form of porous monoliths by means of the ice-segregation-induced self-assembly (ISISA) method coupled with freeze-drying. Physical and chemical parameters were explored in order to fine-tune the microstructure and the incidence on both swelling a...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Minaberry, Yanina Susana, Jobbagy, Matias
Publicado: 2013
Materias:
Aqueous media
Dissolution behavior
Drug release properties
Hyaluronic acids
Physical and chemical parameters
Porous monoliths
Scanning electron microscopy
Thermoanalysis
Organic acids
gentamicin
hyaluronic acid
article
chemical structure
drug release
extracellular matrix
freeze drying
hydrogel
physical parameters
priority journal
scanning electron microscopy
thermal analysis
tuned swelling
Drug Carriers
Gentamicins
Hyaluronic Acid
Hydrogels
Microspheres
Nanostructures
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_15257797_v14_n1_p1_Minaberry
http://hdl.handle.net/20.500.12110/paper_15257797_v14_n1_p1_Minaberry
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
id paper:paper_15257797_v14_n1_p1_Minaberry
record_format dspace
spelling paper:paper_15257797_v14_n1_p1_Minaberry2023-06-08T16:19:35Z Micro/nanostructured hyaluronic acid matrices with tuned swelling and drug release properties Minaberry, Yanina Susana Jobbagy, Matias Aqueous media Dissolution behavior Drug release properties Hyaluronic acids Physical and chemical parameters Porous monoliths Scanning electron microscopy Thermoanalysis Organic acids gentamicin hyaluronic acid article chemical structure drug release extracellular matrix freeze drying hydrogel physical parameters priority journal scanning electron microscopy thermal analysis tuned swelling Drug Carriers Gentamicins Hyaluronic Acid Hydrogels Microspheres Nanostructures Hyaluronic acid (HA) hydrogels were structured in the form of porous monoliths by means of the ice-segregation-induced self-assembly (ISISA) method coupled with freeze-drying. Physical and chemical parameters were explored in order to fine-tune the microstructure and the incidence on both swelling and dissolution behavior in aqueous media. Gentamicin-loaded HA matrices with tuned drug release properties were also prepared; their inherent properties and behavior in solution are discussed in the framework of thermal analysis and scanning electron microscopy inspection. © 2012 American Chemical Society. Fil:Minaberry, Y. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Jobbágy, M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 2013 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_15257797_v14_n1_p1_Minaberry http://hdl.handle.net/20.500.12110/paper_15257797_v14_n1_p1_Minaberry
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic Aqueous media
Dissolution behavior
Drug release properties
Hyaluronic acids
Physical and chemical parameters
Porous monoliths
Scanning electron microscopy
Thermoanalysis
Organic acids
gentamicin
hyaluronic acid
article
chemical structure
drug release
extracellular matrix
freeze drying
hydrogel
physical parameters
priority journal
scanning electron microscopy
thermal analysis
tuned swelling
Drug Carriers
Gentamicins
Hyaluronic Acid
Hydrogels
Microspheres
Nanostructures
spellingShingle Aqueous media
Dissolution behavior
Drug release properties
Hyaluronic acids
Physical and chemical parameters
Porous monoliths
Scanning electron microscopy
Thermoanalysis
Organic acids
gentamicin
hyaluronic acid
article
chemical structure
drug release
extracellular matrix
freeze drying
hydrogel
physical parameters
priority journal
scanning electron microscopy
thermal analysis
tuned swelling
Drug Carriers
Gentamicins
Hyaluronic Acid
Hydrogels
Microspheres
Nanostructures
Minaberry, Yanina Susana
Jobbagy, Matias
Micro/nanostructured hyaluronic acid matrices with tuned swelling and drug release properties
topic_facet Aqueous media
Dissolution behavior
Drug release properties
Hyaluronic acids
Physical and chemical parameters
Porous monoliths
Scanning electron microscopy
Thermoanalysis
Organic acids
gentamicin
hyaluronic acid
article
chemical structure
drug release
extracellular matrix
freeze drying
hydrogel
physical parameters
priority journal
scanning electron microscopy
thermal analysis
tuned swelling
Drug Carriers
Gentamicins
Hyaluronic Acid
Hydrogels
Microspheres
Nanostructures
description Hyaluronic acid (HA) hydrogels were structured in the form of porous monoliths by means of the ice-segregation-induced self-assembly (ISISA) method coupled with freeze-drying. Physical and chemical parameters were explored in order to fine-tune the microstructure and the incidence on both swelling and dissolution behavior in aqueous media. Gentamicin-loaded HA matrices with tuned drug release properties were also prepared; their inherent properties and behavior in solution are discussed in the framework of thermal analysis and scanning electron microscopy inspection. © 2012 American Chemical Society.
author Minaberry, Yanina Susana
Jobbagy, Matias
author_facet Minaberry, Yanina Susana
Jobbagy, Matias
author_sort Minaberry, Yanina Susana
title Micro/nanostructured hyaluronic acid matrices with tuned swelling and drug release properties
title_short Micro/nanostructured hyaluronic acid matrices with tuned swelling and drug release properties
title_full Micro/nanostructured hyaluronic acid matrices with tuned swelling and drug release properties
title_fullStr Micro/nanostructured hyaluronic acid matrices with tuned swelling and drug release properties
title_full_unstemmed Micro/nanostructured hyaluronic acid matrices with tuned swelling and drug release properties
title_sort micro/nanostructured hyaluronic acid matrices with tuned swelling and drug release properties
publishDate 2013
url https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_15257797_v14_n1_p1_Minaberry
http://hdl.handle.net/20.500.12110/paper_15257797_v14_n1_p1_Minaberry
work_keys_str_mv AT minaberryyaninasusana micronanostructuredhyaluronicacidmatriceswithtunedswellinganddrugreleaseproperties
AT jobbagymatias micronanostructuredhyaluronicacidmatriceswithtunedswellinganddrugreleaseproperties
_version_ 1768543720901181440

Ejemplares similares