Benzimidazole as deazapurine analogue for microbial transglycosylation
Benzimidazole nucleosides are compounds with interesting pharmacological properties. Although chemical synthesis of these analogues has been carried out, only few derivatives have been obtained so far using biotransformations. We report herein the biocatalysed preparation of benzimidazole ribo- and...
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2004
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| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_13811177_v29_n1-6_p3_Bentancor http://hdl.handle.net/20.500.12110/paper_13811177_v29_n1-6_p3_Bentancor |
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paper:paper_13811177_v29_n1-6_p3_Bentancor2023-06-08T16:12:19Z Benzimidazole as deazapurine analogue for microbial transglycosylation Benzimidazole Microbial transglycosylation Nucleoside analogues Whole cells Cells Derivatives Synthesis (chemical) Benzimidazole Biotransformations Pharmacological properties Catalysis benzimidazole benzimidazole 2' deoxyriboside benzimidazole riboside purine derivative unclassified drug bacterial cell catalysis conference paper controlled study drug synthesis drug transformation glycosylation microorganism nonhuman Benzimidazole nucleosides are compounds with interesting pharmacological properties. Although chemical synthesis of these analogues has been carried out, only few derivatives have been obtained so far using biotransformations. We report herein the biocatalysed preparation of benzimidazole ribo- and 2′-deoxyribonucleosides by different microbial whole cells that afforded yields between 75 and 85%. © 2004 Elsevier B.V. All rights reserved. 2004 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_13811177_v29_n1-6_p3_Bentancor http://hdl.handle.net/20.500.12110/paper_13811177_v29_n1-6_p3_Bentancor |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Benzimidazole Microbial transglycosylation Nucleoside analogues Whole cells Cells Derivatives Synthesis (chemical) Benzimidazole Biotransformations Pharmacological properties Catalysis benzimidazole benzimidazole 2' deoxyriboside benzimidazole riboside purine derivative unclassified drug bacterial cell catalysis conference paper controlled study drug synthesis drug transformation glycosylation microorganism nonhuman |
| spellingShingle |
Benzimidazole Microbial transglycosylation Nucleoside analogues Whole cells Cells Derivatives Synthesis (chemical) Benzimidazole Biotransformations Pharmacological properties Catalysis benzimidazole benzimidazole 2' deoxyriboside benzimidazole riboside purine derivative unclassified drug bacterial cell catalysis conference paper controlled study drug synthesis drug transformation glycosylation microorganism nonhuman Benzimidazole as deazapurine analogue for microbial transglycosylation |
| topic_facet |
Benzimidazole Microbial transglycosylation Nucleoside analogues Whole cells Cells Derivatives Synthesis (chemical) Benzimidazole Biotransformations Pharmacological properties Catalysis benzimidazole benzimidazole 2' deoxyriboside benzimidazole riboside purine derivative unclassified drug bacterial cell catalysis conference paper controlled study drug synthesis drug transformation glycosylation microorganism nonhuman |
| description |
Benzimidazole nucleosides are compounds with interesting pharmacological properties. Although chemical synthesis of these analogues has been carried out, only few derivatives have been obtained so far using biotransformations. We report herein the biocatalysed preparation of benzimidazole ribo- and 2′-deoxyribonucleosides by different microbial whole cells that afforded yields between 75 and 85%. © 2004 Elsevier B.V. All rights reserved. |
| title |
Benzimidazole as deazapurine analogue for microbial transglycosylation |
| title_short |
Benzimidazole as deazapurine analogue for microbial transglycosylation |
| title_full |
Benzimidazole as deazapurine analogue for microbial transglycosylation |
| title_fullStr |
Benzimidazole as deazapurine analogue for microbial transglycosylation |
| title_full_unstemmed |
Benzimidazole as deazapurine analogue for microbial transglycosylation |
| title_sort |
benzimidazole as deazapurine analogue for microbial transglycosylation |
| publishDate |
2004 |
| url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_13811177_v29_n1-6_p3_Bentancor http://hdl.handle.net/20.500.12110/paper_13811177_v29_n1-6_p3_Bentancor |
| _version_ |
1768545892594352128 |