The small GTP-binding protein RhoA regulates c-jun by a ROCK-JNK signaling axis

RhoA regulates the actin cytoskeleton and the expression of genes associated with cell proliferation. This includes c-fos and c-jun, which are members of the AP1 family of transcription factors that play a key role in normal and aberrant cell growth. Whereas RhoA stimulates the c-fos SRE by a recent...

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Guardado en:
Detalles Bibliográficos
Publicado: 2004
Materias:
actin
activating transcription factor 2
protein
protein c fos
protein c jun
protein kinase
protein Rock
RhoA guanine nucleotide binding protein
stress activated protein kinase
transcription factor AP 1
unclassified drug
animal cell
article
cell growth
cell nucleus
cell proliferation
controlled study
cytoskeleton
downstream processing
enzyme activation
enzyme activity
gene expression
human
human cell
molecular mechanics
mouse
nonhuman
polymerization
promoter region
protein binding
protein expression
protein family
protein function
protein phosphorylation
regulatory mechanism
serum responsive element
signal transduction
stimulation
Actin Depolymerizing Factors
Actins
Activating Transcription Factor 2
Animals
Cell Line
Cyclic AMP Response Element-Binding Protein
Cytoskeleton
Enzyme Activation
Enzyme Inhibitors
Gene Expression Regulation
Humans
Intracellular Signaling Peptides and Proteins
JNK Mitogen-Activated Protein Kinases
Lysophospholipids
Mice
Microfilament Proteins
Mitogen-Activated Protein Kinases
NIH 3T3 Cells
Promoter Regions (Genetics)
Protein Kinases
Protein-Serine-Threonine Kinases
Proto-Oncogene Proteins c-jun
rhoA GTP-Binding Protein
Signal Transduction
Transcription Factors
Animalia
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_10972765_v14_n1_p29_Marinissen
http://hdl.handle.net/20.500.12110/paper_10972765_v14_n1_p29_Marinissen
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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