Work status among patients with ankylosing spondylitis in Argentina

OBJECTIVE:: To evaluate work status and its determinants among ankylosing spondylitis (AS) patients in our country. MATERIALS AND METHODS:: We carried out a case-control study, including AS patients older than 16-year-old. Demographic, socioeconomic, and employment data were collected. Individuals f...

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Publicado:	2008
Materias:	Ankylosing spondylitis Disability Fatigue Quality of life Work adult aged ankylosing spondylitis Argentina article comorbidity controlled study depression disease activity employment status fatigue female human major clinical study male priority journal quality of life scoring system structured questionnaire case control study disability employment middle aged statistical model statistics unemployment Adult Case-Control Studies Depression Disability Evaluation Employment Female Humans Logistic Models Male Middle Aged Quality of Life Spondylitis, Ankylosing Unemployment
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_10761608_v14_n5_p273_Marengo http://hdl.handle.net/20.500.12110/paper_10761608_v14_n5_p273_Marengo
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	paper:paper_10761608_v14_n5_p273_Marengo
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spelling	paper:paper_10761608_v14_n5_p273_Marengo2023-06-08T16:05:20Z Work status among patients with ankylosing spondylitis in Argentina Ankylosing spondylitis Disability Fatigue Quality of life Work adult aged ankylosing spondylitis Argentina article comorbidity controlled study depression disease activity employment status fatigue female human major clinical study male priority journal quality of life scoring system structured questionnaire ankylosing spondylitis case control study depression disability employment middle aged statistical model statistics unemployment Adult Argentina Case-Control Studies Depression Disability Evaluation Employment Female Humans Logistic Models Male Middle Aged Quality of Life Spondylitis, Ankylosing Unemployment OBJECTIVE:: To evaluate work status and its determinants among ankylosing spondylitis (AS) patients in our country. MATERIALS AND METHODS:: We carried out a case-control study, including AS patients older than 16-year-old. Demographic, socioeconomic, and employment data were collected. Individuals from the general population matched by age, sex, and socioeconomic level served as the control group. Functional capacity was evaluated by bath ankylosing spondylitis functional index (BASFI) and health assessment questionnaire (HAQ-S) and disease activity by bath ankylosing spondylitis disease activity index (BASDAI). All patients completed quality of life (ASQol), depression (CES-D), and fatigue (FSS)-validated questionnaires. RESULTS:: Sixty-four patients with AS (57 men) and 93 controls (83 men) were included. The frequency of retirement due to age was comparable in both groups, however, a significantly larger number of patients with AS were retired due to disability: 6 (9.4%) versus 0 (P = 0.004). Patients with AS had a significantly greater number of comorbidities than controls (78.7% vs. 31.5%, P = 1 × 10). Sixteen patients (26.2%) were unemployed compared with 4 controls (4.5%) (P = 0.001). Permanence at work was significantly lower in patients (median age 58, SD 54-61 years) versus controls (median age 66, SD 63-68 years) (log Rank P = 0.001). There were less full-time workers (71% vs. 87%, P = 0.03) and higher number of sick leave days (6.56 ± 13 vs. 2.13 ± 4.5, P = 0.01) in AS patients than controls. Unemployed patients had significantly worst quality of life, disease activity, and depression scores than employed patients. In the multivariate analysis, the primary variable associated to unemployment was depression [Odds Ratio (OR): 20, 95% confidence interval (CI), 1.69-258, P = 0.001] followed by disease activity (OR: 1.05, 95% CI, 1-1.1, P = 0.04) and age (OR: 1.1, 95% CI, 1.02-1.21, P = 0.01) as secondary variables. CONCLUSIONS:: The frequency of work disability among our patients with AS was significantly higher than in age, sex, and socioeconomic matched population. The main variable associated with work disability and unemployment was depression. Whether this factor is contributing to or is a result of disability is not known. © 2008 Lippincott Williams & Wilkins. 2008 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_10761608_v14_n5_p273_Marengo http://hdl.handle.net/20.500.12110/paper_10761608_v14_n5_p273_Marengo
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	Ankylosing spondylitis Disability Fatigue Quality of life Work adult aged ankylosing spondylitis Argentina article comorbidity controlled study depression disease activity employment status fatigue female human major clinical study male priority journal quality of life scoring system structured questionnaire ankylosing spondylitis case control study depression disability employment middle aged statistical model statistics unemployment Adult Argentina Case-Control Studies Depression Disability Evaluation Employment Female Humans Logistic Models Male Middle Aged Quality of Life Spondylitis, Ankylosing Unemployment
spellingShingle	Ankylosing spondylitis Disability Fatigue Quality of life Work adult aged ankylosing spondylitis Argentina article comorbidity controlled study depression disease activity employment status fatigue female human major clinical study male priority journal quality of life scoring system structured questionnaire ankylosing spondylitis case control study depression disability employment middle aged statistical model statistics unemployment Adult Argentina Case-Control Studies Depression Disability Evaluation Employment Female Humans Logistic Models Male Middle Aged Quality of Life Spondylitis, Ankylosing Unemployment Work status among patients with ankylosing spondylitis in Argentina
topic_facet	Ankylosing spondylitis Disability Fatigue Quality of life Work adult aged ankylosing spondylitis Argentina article comorbidity controlled study depression disease activity employment status fatigue female human major clinical study male priority journal quality of life scoring system structured questionnaire ankylosing spondylitis case control study depression disability employment middle aged statistical model statistics unemployment Adult Argentina Case-Control Studies Depression Disability Evaluation Employment Female Humans Logistic Models Male Middle Aged Quality of Life Spondylitis, Ankylosing Unemployment
description	OBJECTIVE:: To evaluate work status and its determinants among ankylosing spondylitis (AS) patients in our country. MATERIALS AND METHODS:: We carried out a case-control study, including AS patients older than 16-year-old. Demographic, socioeconomic, and employment data were collected. Individuals from the general population matched by age, sex, and socioeconomic level served as the control group. Functional capacity was evaluated by bath ankylosing spondylitis functional index (BASFI) and health assessment questionnaire (HAQ-S) and disease activity by bath ankylosing spondylitis disease activity index (BASDAI). All patients completed quality of life (ASQol), depression (CES-D), and fatigue (FSS)-validated questionnaires. RESULTS:: Sixty-four patients with AS (57 men) and 93 controls (83 men) were included. The frequency of retirement due to age was comparable in both groups, however, a significantly larger number of patients with AS were retired due to disability: 6 (9.4%) versus 0 (P = 0.004). Patients with AS had a significantly greater number of comorbidities than controls (78.7% vs. 31.5%, P = 1 × 10). Sixteen patients (26.2%) were unemployed compared with 4 controls (4.5%) (P = 0.001). Permanence at work was significantly lower in patients (median age 58, SD 54-61 years) versus controls (median age 66, SD 63-68 years) (log Rank P = 0.001). There were less full-time workers (71% vs. 87%, P = 0.03) and higher number of sick leave days (6.56 ± 13 vs. 2.13 ± 4.5, P = 0.01) in AS patients than controls. Unemployed patients had significantly worst quality of life, disease activity, and depression scores than employed patients. In the multivariate analysis, the primary variable associated to unemployment was depression [Odds Ratio (OR): 20, 95% confidence interval (CI), 1.69-258, P = 0.001] followed by disease activity (OR: 1.05, 95% CI, 1-1.1, P = 0.04) and age (OR: 1.1, 95% CI, 1.02-1.21, P = 0.01) as secondary variables. CONCLUSIONS:: The frequency of work disability among our patients with AS was significantly higher than in age, sex, and socioeconomic matched population. The main variable associated with work disability and unemployment was depression. Whether this factor is contributing to or is a result of disability is not known. © 2008 Lippincott Williams & Wilkins.
title	Work status among patients with ankylosing spondylitis in Argentina
title_short	Work status among patients with ankylosing spondylitis in Argentina
title_full	Work status among patients with ankylosing spondylitis in Argentina
title_fullStr	Work status among patients with ankylosing spondylitis in Argentina
title_full_unstemmed	Work status among patients with ankylosing spondylitis in Argentina
title_sort	work status among patients with ankylosing spondylitis in argentina
publishDate	2008
url	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_10761608_v14_n5_p273_Marengo http://hdl.handle.net/20.500.12110/paper_10761608_v14_n5_p273_Marengo
_version_	1768541949474635776

Work status among patients with ankylosing spondylitis in Argentina

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