Enzyme-catalyzed preparation of novel fatty acid derivatives of pyridoxine with surfactant activity

A series of novel fatty acid derivatives of pyridoxine, one of the three members of the vitamin B6 group, has been prepared. These products were obtained using an enzymatic approach. Several lipases catalyzed esterification and transesterification reactions of pyridoxine with carboxylic acid or alky...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Baldessari, Alicia, Mangone, Constanza Pía
Publicado:	2002
Materias:	Enzyme-catalyzed Fatty acids Pyridoxine Surfactants Biosynthesis Carboxylic acids Derivatives Drug products Enzymes Esterification Food additives Surface active agents Vitamins Regioselective Nitrogen compounds (5 hydroxy 4 hydroxymethyl 6 methylpyridin 3 yl)methyl 13 docosenoic acid (5 hydroxy 4 hydroxymethyl 6 methylpyridin 3 yl)methyl 5,8,11,14 eicosatetraenoic acid (5 hydroxy 4 hydroxymethyl 6 methylpyridin 3 yl)methyl 9 octadecanoic acid (5 hydroxy 4 hydroxymethyl 6 methylpyridin 3 yl)methyl 9,12 octadecanoic acid (5 hydroxy 4 hydroxymethyl 6 methylpyridin 3 yl)methyl 9,12,15 octadecatrienoic acid (5 hydroxy 4 hydroxymethyl 6 methylpyridin 3 yl)methyleicosanoic acid (5 hydroxy 4 hydroxymethyl 6 methylpyridin 3 yl)methyloctadecanoic acid carboxylic acid fatty acid derivative food additive pyridoxine derivative surfactant triacylglycerol lipase unclassified drug acylation article catalysis cosmetic industry drug activity drug formulation drug synthesis enzymatic assay enzyme substrate nonhuman pancreas pharmaceutical engineering swine Sus scrofa
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_10242422_v20_n4_p275_Baldessari http://hdl.handle.net/20.500.12110/paper_10242422_v20_n4_p275_Baldessari
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	paper:paper_10242422_v20_n4_p275_Baldessari
record_format	dspace
spelling	paper:paper_10242422_v20_n4_p275_Baldessari2025-07-30T18:36:11Z Enzyme-catalyzed preparation of novel fatty acid derivatives of pyridoxine with surfactant activity Baldessari, Alicia Mangone, Constanza Pía Enzyme-catalyzed Fatty acids Pyridoxine Surfactants Biosynthesis Carboxylic acids Derivatives Drug products Enzymes Esterification Fatty acids Food additives Surface active agents Vitamins Regioselective Nitrogen compounds (5 hydroxy 4 hydroxymethyl 6 methylpyridin 3 yl)methyl 13 docosenoic acid (5 hydroxy 4 hydroxymethyl 6 methylpyridin 3 yl)methyl 5,8,11,14 eicosatetraenoic acid (5 hydroxy 4 hydroxymethyl 6 methylpyridin 3 yl)methyl 9 octadecanoic acid (5 hydroxy 4 hydroxymethyl 6 methylpyridin 3 yl)methyl 9,12 octadecanoic acid (5 hydroxy 4 hydroxymethyl 6 methylpyridin 3 yl)methyl 9,12,15 octadecatrienoic acid (5 hydroxy 4 hydroxymethyl 6 methylpyridin 3 yl)methyleicosanoic acid (5 hydroxy 4 hydroxymethyl 6 methylpyridin 3 yl)methyloctadecanoic acid carboxylic acid fatty acid derivative food additive pyridoxine derivative surfactant triacylglycerol lipase unclassified drug acylation article catalysis cosmetic industry drug activity drug formulation drug synthesis enzymatic assay enzyme substrate nonhuman pancreas pharmaceutical engineering swine Sus scrofa A series of novel fatty acid derivatives of pyridoxine, one of the three members of the vitamin B6 group, has been prepared. These products were obtained using an enzymatic approach. Several lipases catalyzed esterification and transesterification reactions of pyridoxine with carboxylic acid or alkyl carboxylates showed a remarkable regioselective behavior; only monoacyl derivatives were obtained. The surfactant activity, composition and clean enzymatic methodology applied in the preparation of these products make them useful as ingredients in cosmetic and pharmaceutical formulations or food additives. Fil:Baldessari, A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Mangone, C.P. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 2002 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_10242422_v20_n4_p275_Baldessari http://hdl.handle.net/20.500.12110/paper_10242422_v20_n4_p275_Baldessari
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	Enzyme-catalyzed Fatty acids Pyridoxine Surfactants Biosynthesis Carboxylic acids Derivatives Drug products Enzymes Esterification Fatty acids Food additives Surface active agents Vitamins Regioselective Nitrogen compounds (5 hydroxy 4 hydroxymethyl 6 methylpyridin 3 yl)methyl 13 docosenoic acid (5 hydroxy 4 hydroxymethyl 6 methylpyridin 3 yl)methyl 5,8,11,14 eicosatetraenoic acid (5 hydroxy 4 hydroxymethyl 6 methylpyridin 3 yl)methyl 9 octadecanoic acid (5 hydroxy 4 hydroxymethyl 6 methylpyridin 3 yl)methyl 9,12 octadecanoic acid (5 hydroxy 4 hydroxymethyl 6 methylpyridin 3 yl)methyl 9,12,15 octadecatrienoic acid (5 hydroxy 4 hydroxymethyl 6 methylpyridin 3 yl)methyleicosanoic acid (5 hydroxy 4 hydroxymethyl 6 methylpyridin 3 yl)methyloctadecanoic acid carboxylic acid fatty acid derivative food additive pyridoxine derivative surfactant triacylglycerol lipase unclassified drug acylation article catalysis cosmetic industry drug activity drug formulation drug synthesis enzymatic assay enzyme substrate nonhuman pancreas pharmaceutical engineering swine Sus scrofa
spellingShingle	Enzyme-catalyzed Fatty acids Pyridoxine Surfactants Biosynthesis Carboxylic acids Derivatives Drug products Enzymes Esterification Fatty acids Food additives Surface active agents Vitamins Regioselective Nitrogen compounds (5 hydroxy 4 hydroxymethyl 6 methylpyridin 3 yl)methyl 13 docosenoic acid (5 hydroxy 4 hydroxymethyl 6 methylpyridin 3 yl)methyl 5,8,11,14 eicosatetraenoic acid (5 hydroxy 4 hydroxymethyl 6 methylpyridin 3 yl)methyl 9 octadecanoic acid (5 hydroxy 4 hydroxymethyl 6 methylpyridin 3 yl)methyl 9,12 octadecanoic acid (5 hydroxy 4 hydroxymethyl 6 methylpyridin 3 yl)methyl 9,12,15 octadecatrienoic acid (5 hydroxy 4 hydroxymethyl 6 methylpyridin 3 yl)methyleicosanoic acid (5 hydroxy 4 hydroxymethyl 6 methylpyridin 3 yl)methyloctadecanoic acid carboxylic acid fatty acid derivative food additive pyridoxine derivative surfactant triacylglycerol lipase unclassified drug acylation article catalysis cosmetic industry drug activity drug formulation drug synthesis enzymatic assay enzyme substrate nonhuman pancreas pharmaceutical engineering swine Sus scrofa Baldessari, Alicia Mangone, Constanza Pía Enzyme-catalyzed preparation of novel fatty acid derivatives of pyridoxine with surfactant activity
topic_facet	Enzyme-catalyzed Fatty acids Pyridoxine Surfactants Biosynthesis Carboxylic acids Derivatives Drug products Enzymes Esterification Fatty acids Food additives Surface active agents Vitamins Regioselective Nitrogen compounds (5 hydroxy 4 hydroxymethyl 6 methylpyridin 3 yl)methyl 13 docosenoic acid (5 hydroxy 4 hydroxymethyl 6 methylpyridin 3 yl)methyl 5,8,11,14 eicosatetraenoic acid (5 hydroxy 4 hydroxymethyl 6 methylpyridin 3 yl)methyl 9 octadecanoic acid (5 hydroxy 4 hydroxymethyl 6 methylpyridin 3 yl)methyl 9,12 octadecanoic acid (5 hydroxy 4 hydroxymethyl 6 methylpyridin 3 yl)methyl 9,12,15 octadecatrienoic acid (5 hydroxy 4 hydroxymethyl 6 methylpyridin 3 yl)methyleicosanoic acid (5 hydroxy 4 hydroxymethyl 6 methylpyridin 3 yl)methyloctadecanoic acid carboxylic acid fatty acid derivative food additive pyridoxine derivative surfactant triacylglycerol lipase unclassified drug acylation article catalysis cosmetic industry drug activity drug formulation drug synthesis enzymatic assay enzyme substrate nonhuman pancreas pharmaceutical engineering swine Sus scrofa
description	A series of novel fatty acid derivatives of pyridoxine, one of the three members of the vitamin B6 group, has been prepared. These products were obtained using an enzymatic approach. Several lipases catalyzed esterification and transesterification reactions of pyridoxine with carboxylic acid or alkyl carboxylates showed a remarkable regioselective behavior; only monoacyl derivatives were obtained. The surfactant activity, composition and clean enzymatic methodology applied in the preparation of these products make them useful as ingredients in cosmetic and pharmaceutical formulations or food additives.
author	Baldessari, Alicia Mangone, Constanza Pía
author_facet	Baldessari, Alicia Mangone, Constanza Pía
author_sort	Baldessari, Alicia
title	Enzyme-catalyzed preparation of novel fatty acid derivatives of pyridoxine with surfactant activity
title_short	Enzyme-catalyzed preparation of novel fatty acid derivatives of pyridoxine with surfactant activity
title_full	Enzyme-catalyzed preparation of novel fatty acid derivatives of pyridoxine with surfactant activity
title_fullStr	Enzyme-catalyzed preparation of novel fatty acid derivatives of pyridoxine with surfactant activity
title_full_unstemmed	Enzyme-catalyzed preparation of novel fatty acid derivatives of pyridoxine with surfactant activity
title_sort	enzyme-catalyzed preparation of novel fatty acid derivatives of pyridoxine with surfactant activity
publishDate	2002
url	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_10242422_v20_n4_p275_Baldessari http://hdl.handle.net/20.500.12110/paper_10242422_v20_n4_p275_Baldessari
work_keys_str_mv	AT baldessarialicia enzymecatalyzedpreparationofnovelfattyacidderivativesofpyridoxinewithsurfactantactivity AT mangoneconstanzapia enzymecatalyzedpreparationofnovelfattyacidderivativesofpyridoxinewithsurfactantactivity
_version_	1840324501942829056

Enzyme-catalyzed preparation of novel fatty acid derivatives of pyridoxine with surfactant activity

Ejemplares similares