Unsuspected hyperhomocysteinemia in chronically anticoagulated patients
Hyperhomocysteinemia is a risk factor for arterial and venous thrombosis. The aim of this study was to evaluate plasmatic homocysteine levels in patients under chronic anticoagulant treatment with dietary restriction of green vegetables. This kind of food is a very important source not only of vitam...
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2001
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| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09575235_v12_n1_p79_Murua http://hdl.handle.net/20.500.12110/paper_09575235_v12_n1_p79_Murua |
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paper:paper_09575235_v12_n1_p79_Murua2023-06-08T15:56:37Z Unsuspected hyperhomocysteinemia in chronically anticoagulated patients Anticoagulant treatment Diet Hyperhomocysteinemia anticoagulant agent folic acid derivative homocysteine vitamin K group adult anticoagulation artery thrombosis article clinical article controlled study diet restriction human hyperhomocysteinemia metabolism priority journal risk factor vegetable vein thrombosis Aged Anticoagulants Case-Control Studies Chronic Disease Diet Folic Acid Homocysteine Humans Hyperhomocysteinemia Middle Aged Vegetables Vitamin K Hyperhomocysteinemia is a risk factor for arterial and venous thrombosis. The aim of this study was to evaluate plasmatic homocysteine levels in patients under chronic anticoagulant treatment with dietary restriction of green vegetables. This kind of food is a very important source not only of vitamin K but also of folates, which are involved in Hcy metabolism. It is known that the lower the folate levels, the higher the Hcy concentration, so we suspected that these patients could show hyperhomocysteinemia. A group of patients receiving oral anticoagulant treatment and a restricted diet (Group 1, n =20) was compared with a group of untreated subjects of a similar age that were not on a restricted diet (Group II, n = 35). Group I showed significantly higher levels of plasmatic Hcy and significantly lower levels of serum folate than Group II. Therefore, a diet restricted in vitamin K applied to oral anticoagulated patients could induce an unwanted increase of homocysteine levels. © 2001 Lippincott Williams & Wilkins. 2001 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09575235_v12_n1_p79_Murua http://hdl.handle.net/20.500.12110/paper_09575235_v12_n1_p79_Murua |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Anticoagulant treatment Diet Hyperhomocysteinemia anticoagulant agent folic acid derivative homocysteine vitamin K group adult anticoagulation artery thrombosis article clinical article controlled study diet restriction human hyperhomocysteinemia metabolism priority journal risk factor vegetable vein thrombosis Aged Anticoagulants Case-Control Studies Chronic Disease Diet Folic Acid Homocysteine Humans Hyperhomocysteinemia Middle Aged Vegetables Vitamin K |
| spellingShingle |
Anticoagulant treatment Diet Hyperhomocysteinemia anticoagulant agent folic acid derivative homocysteine vitamin K group adult anticoagulation artery thrombosis article clinical article controlled study diet restriction human hyperhomocysteinemia metabolism priority journal risk factor vegetable vein thrombosis Aged Anticoagulants Case-Control Studies Chronic Disease Diet Folic Acid Homocysteine Humans Hyperhomocysteinemia Middle Aged Vegetables Vitamin K Unsuspected hyperhomocysteinemia in chronically anticoagulated patients |
| topic_facet |
Anticoagulant treatment Diet Hyperhomocysteinemia anticoagulant agent folic acid derivative homocysteine vitamin K group adult anticoagulation artery thrombosis article clinical article controlled study diet restriction human hyperhomocysteinemia metabolism priority journal risk factor vegetable vein thrombosis Aged Anticoagulants Case-Control Studies Chronic Disease Diet Folic Acid Homocysteine Humans Hyperhomocysteinemia Middle Aged Vegetables Vitamin K |
| description |
Hyperhomocysteinemia is a risk factor for arterial and venous thrombosis. The aim of this study was to evaluate plasmatic homocysteine levels in patients under chronic anticoagulant treatment with dietary restriction of green vegetables. This kind of food is a very important source not only of vitamin K but also of folates, which are involved in Hcy metabolism. It is known that the lower the folate levels, the higher the Hcy concentration, so we suspected that these patients could show hyperhomocysteinemia. A group of patients receiving oral anticoagulant treatment and a restricted diet (Group 1, n =20) was compared with a group of untreated subjects of a similar age that were not on a restricted diet (Group II, n = 35). Group I showed significantly higher levels of plasmatic Hcy and significantly lower levels of serum folate than Group II. Therefore, a diet restricted in vitamin K applied to oral anticoagulated patients could induce an unwanted increase of homocysteine levels. © 2001 Lippincott Williams & Wilkins. |
| title |
Unsuspected hyperhomocysteinemia in chronically anticoagulated patients |
| title_short |
Unsuspected hyperhomocysteinemia in chronically anticoagulated patients |
| title_full |
Unsuspected hyperhomocysteinemia in chronically anticoagulated patients |
| title_fullStr |
Unsuspected hyperhomocysteinemia in chronically anticoagulated patients |
| title_full_unstemmed |
Unsuspected hyperhomocysteinemia in chronically anticoagulated patients |
| title_sort |
unsuspected hyperhomocysteinemia in chronically anticoagulated patients |
| publishDate |
2001 |
| url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09575235_v12_n1_p79_Murua http://hdl.handle.net/20.500.12110/paper_09575235_v12_n1_p79_Murua |
| _version_ |
1768543619870883840 |