QTL for survival to UV-C radiation in Drosophila melanogaster

Purpose: The aim of this study was to investigate tolerance to UV-C (ultraviolet C, 280-100 nm) radiation in Drosophila melanogaster, implementing a quantitative trait locus (QTL) mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. Materials...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Gomez, Federico Hernan, Norry, Fabian Marcelo
Publicado:	2013
Materias:	Environmental stress Multiple trait mapping Thermotolerance Ultraviolet radiation allele animal experiment article chromosome 2 Drosophila melanogaster female gene mapping genetic variability genotype heat tolerance male nonhuman Northern Hemisphere priority journal quantitative trait locus radiation dose Southern Hemisphere survival ultraviolet C radiation Animals Dose-Response Relationship, Radiation Quantitative Trait Loci Radiation Dosage Radiation Tolerance Survival Rate Ultraviolet Rays
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09553002_v89_n7_p583_Gomez http://hdl.handle.net/20.500.12110/paper_09553002_v89_n7_p583_Gomez
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	paper:paper_09553002_v89_n7_p583_Gomez
record_format	dspace
spelling	paper:paper_09553002_v89_n7_p583_Gomez2023-06-08T15:55:53Z QTL for survival to UV-C radiation in Drosophila melanogaster Gomez, Federico Hernan Norry, Fabian Marcelo Environmental stress Multiple trait mapping Thermotolerance Ultraviolet radiation allele animal experiment article chromosome 2 Drosophila melanogaster female gene mapping genetic variability genotype heat tolerance male nonhuman Northern Hemisphere priority journal quantitative trait locus radiation dose Southern Hemisphere survival ultraviolet C radiation Animals Dose-Response Relationship, Radiation Drosophila melanogaster Quantitative Trait Loci Radiation Dosage Radiation Tolerance Survival Rate Ultraviolet Rays Drosophila melanogaster Purpose: The aim of this study was to investigate tolerance to UV-C (ultraviolet C, 280-100 nm) radiation in Drosophila melanogaster, implementing a quantitative trait locus (QTL) mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. Materials and methods: We performed a QTL scan in D. melanogaster recombinant inbred lines (RIL) constructed from parental stocks derived from a crossing between northern and southern hemisphere populations that segregated substantial genetic variation in thermal resistance in a previous study. Here, two experimental treatments were implemented: Continuous and cyclic UV-C radiation. Results: Significant QTL were detected on all three major chromosomes. Among these, multiple trait composite interval mapping revealed a significant QTL in the pericentromeric region of chromosome 2, a genome region consistently implicated in thermotolerance in previous studies. Conclusions: This study shows substantial genetic variation for UV-C radiation resistance in D. melanogaster, with QTL for survival to UV-C radiation generally overlapping with major thermotolerance QTL. The genetic architecture of UV-C radiation resistance appears to be more complex in continuously irradiated individuals. © 2013 Informa UK, Ltd. Fil:Gomez, F.H. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Norry, F.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 2013 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09553002_v89_n7_p583_Gomez http://hdl.handle.net/20.500.12110/paper_09553002_v89_n7_p583_Gomez
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	Environmental stress Multiple trait mapping Thermotolerance Ultraviolet radiation allele animal experiment article chromosome 2 Drosophila melanogaster female gene mapping genetic variability genotype heat tolerance male nonhuman Northern Hemisphere priority journal quantitative trait locus radiation dose Southern Hemisphere survival ultraviolet C radiation Animals Dose-Response Relationship, Radiation Drosophila melanogaster Quantitative Trait Loci Radiation Dosage Radiation Tolerance Survival Rate Ultraviolet Rays Drosophila melanogaster
spellingShingle	Environmental stress Multiple trait mapping Thermotolerance Ultraviolet radiation allele animal experiment article chromosome 2 Drosophila melanogaster female gene mapping genetic variability genotype heat tolerance male nonhuman Northern Hemisphere priority journal quantitative trait locus radiation dose Southern Hemisphere survival ultraviolet C radiation Animals Dose-Response Relationship, Radiation Drosophila melanogaster Quantitative Trait Loci Radiation Dosage Radiation Tolerance Survival Rate Ultraviolet Rays Drosophila melanogaster Gomez, Federico Hernan Norry, Fabian Marcelo QTL for survival to UV-C radiation in Drosophila melanogaster
topic_facet	Environmental stress Multiple trait mapping Thermotolerance Ultraviolet radiation allele animal experiment article chromosome 2 Drosophila melanogaster female gene mapping genetic variability genotype heat tolerance male nonhuman Northern Hemisphere priority journal quantitative trait locus radiation dose Southern Hemisphere survival ultraviolet C radiation Animals Dose-Response Relationship, Radiation Drosophila melanogaster Quantitative Trait Loci Radiation Dosage Radiation Tolerance Survival Rate Ultraviolet Rays Drosophila melanogaster
description	Purpose: The aim of this study was to investigate tolerance to UV-C (ultraviolet C, 280-100 nm) radiation in Drosophila melanogaster, implementing a quantitative trait locus (QTL) mapping approach. This is of interest to test for genetic variation in survival to UV (ultraviolet) radiation. Materials and methods: We performed a QTL scan in D. melanogaster recombinant inbred lines (RIL) constructed from parental stocks derived from a crossing between northern and southern hemisphere populations that segregated substantial genetic variation in thermal resistance in a previous study. Here, two experimental treatments were implemented: Continuous and cyclic UV-C radiation. Results: Significant QTL were detected on all three major chromosomes. Among these, multiple trait composite interval mapping revealed a significant QTL in the pericentromeric region of chromosome 2, a genome region consistently implicated in thermotolerance in previous studies. Conclusions: This study shows substantial genetic variation for UV-C radiation resistance in D. melanogaster, with QTL for survival to UV-C radiation generally overlapping with major thermotolerance QTL. The genetic architecture of UV-C radiation resistance appears to be more complex in continuously irradiated individuals. © 2013 Informa UK, Ltd.
author	Gomez, Federico Hernan Norry, Fabian Marcelo
author_facet	Gomez, Federico Hernan Norry, Fabian Marcelo
author_sort	Gomez, Federico Hernan
title	QTL for survival to UV-C radiation in Drosophila melanogaster
title_short	QTL for survival to UV-C radiation in Drosophila melanogaster
title_full	QTL for survival to UV-C radiation in Drosophila melanogaster
title_fullStr	QTL for survival to UV-C radiation in Drosophila melanogaster
title_full_unstemmed	QTL for survival to UV-C radiation in Drosophila melanogaster
title_sort	qtl for survival to uv-c radiation in drosophila melanogaster
publishDate	2013
url	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09553002_v89_n7_p583_Gomez http://hdl.handle.net/20.500.12110/paper_09553002_v89_n7_p583_Gomez
work_keys_str_mv	AT gomezfedericohernan qtlforsurvivaltouvcradiationindrosophilamelanogaster AT norryfabianmarcelo qtlforsurvivaltouvcradiationindrosophilamelanogaster
_version_	1768545016304631808

QTL for survival to UV-C radiation in Drosophila melanogaster

Ejemplares similares