An antiviral meliacarpin from leaves of Melia azedarach L.

Bioassay guided purification of the ethyl acetate extract of leaves of Melia azedarach led to the isolation of the limonoid 1-cinnamoyl-3,11-dihydroxymeliacarpin, which showed IC50 values of 6 μM and 20 μM for vesicular stomatitis (VSV) and herpes simplex (HSV-1) viruses, respectively. Its structure...

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Guardado en:
Detalles Bibliográficos
Publicado: 2003
Materias:
Antiviral Activity
Limonoids
Melia azedarach L.
Melia azedarach
Simplexvirus
Vesicular stomatitis virus
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09395075_v58_n3-4_p215_Alche
http://hdl.handle.net/20.500.12110/paper_09395075_v58_n3-4_p215_Alche
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
id paper:paper_09395075_v58_n3-4_p215_Alche
record_format dspace
spelling paper:paper_09395075_v58_n3-4_p215_Alche2023-06-08T15:53:27Z An antiviral meliacarpin from leaves of Melia azedarach L. Antiviral Activity Limonoids Melia azedarach L. Melia azedarach Melia azedarach Simplexvirus Vesicular stomatitis virus Bioassay guided purification of the ethyl acetate extract of leaves of Melia azedarach led to the isolation of the limonoid 1-cinnamoyl-3,11-dihydroxymeliacarpin, which showed IC50 values of 6 μM and 20 μM for vesicular stomatitis (VSV) and herpes simplex (HSV-1) viruses, respectively. Its structure was established by spectroscopic methods. 2003 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09395075_v58_n3-4_p215_Alche http://hdl.handle.net/20.500.12110/paper_09395075_v58_n3-4_p215_Alche
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic Antiviral Activity
Limonoids
Melia azedarach L.
Melia azedarach
Melia azedarach
Simplexvirus
Vesicular stomatitis virus
spellingShingle Antiviral Activity
Limonoids
Melia azedarach L.
Melia azedarach
Melia azedarach
Simplexvirus
Vesicular stomatitis virus
An antiviral meliacarpin from leaves of Melia azedarach L.
topic_facet Antiviral Activity
Limonoids
Melia azedarach L.
Melia azedarach
Melia azedarach
Simplexvirus
Vesicular stomatitis virus
description Bioassay guided purification of the ethyl acetate extract of leaves of Melia azedarach led to the isolation of the limonoid 1-cinnamoyl-3,11-dihydroxymeliacarpin, which showed IC50 values of 6 μM and 20 μM for vesicular stomatitis (VSV) and herpes simplex (HSV-1) viruses, respectively. Its structure was established by spectroscopic methods.
title An antiviral meliacarpin from leaves of Melia azedarach L.
title_short An antiviral meliacarpin from leaves of Melia azedarach L.
title_full An antiviral meliacarpin from leaves of Melia azedarach L.
title_fullStr An antiviral meliacarpin from leaves of Melia azedarach L.
title_full_unstemmed An antiviral meliacarpin from leaves of Melia azedarach L.
title_sort antiviral meliacarpin from leaves of melia azedarach l.
publishDate 2003
url https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09395075_v58_n3-4_p215_Alche
http://hdl.handle.net/20.500.12110/paper_09395075_v58_n3-4_p215_Alche
_version_ 1768542371622944768

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