Association between nutritional indicators and infectivity of dogs seroreactive for Trypanosoma cruzi in a rural area of northwestern Argentina

The association between the nutritional state of mongrel dogs naturally infected with Trypanosoma cruzi and their infectivity to Triatoma infestans bugs and immune response to Trypanosoma cruzi were studied in the rural village of Amamá, northwestern Argentina. All of the 97 evaluated dogs were clas...

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Detalles Bibliográficos
Autores principales: Gurtler, Ricardo Esteban, Cecere, Maria Carla, Rubel, Diana Nora, Lauricella, Marta Alicia, Hansen, Diana Silvia
Publicado: 2001
Materias:
animal experiment
animal tissue
article
bone structure
facial expression
hematocrit
immune response
intermediate host
muscle development
nonhuman
nutritional status
parasite virulence
pathogenesis
priority journal
reservoir
serology
skinfold thickness
survival
Triatoma infestans
Trypanosoma cruzi
trypanosomiasis
Animals
Antibodies, Protozoan
Argentina
Blood Proteins
Chagas Disease
Cross-Sectional Studies
Dog Diseases
Dogs
Ectoparasitic Infestations
Female
Hematocrit
Insect Vectors
Male
Nutrition Disorders
Nutritional Status
Skinfold Thickness
Survival Rate
Triatoma
Animalia
Canis familiaris
Protozoa
Trypanosoma
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09320113_v87_n3_p208_Petersen
http://hdl.handle.net/20.500.12110/paper_09320113_v87_n3_p208_Petersen
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
id paper:paper_09320113_v87_n3_p208_Petersen
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spelling paper:paper_09320113_v87_n3_p208_Petersen2023-06-08T15:53:02Z Association between nutritional indicators and infectivity of dogs seroreactive for Trypanosoma cruzi in a rural area of northwestern Argentina Gurtler, Ricardo Esteban Cecere, Maria Carla Rubel, Diana Nora Lauricella, Marta Alicia Hansen, Diana Silvia animal experiment animal tissue article bone structure facial expression hematocrit immune response intermediate host muscle development nonhuman nutritional status parasite virulence pathogenesis priority journal reservoir serology skinfold thickness survival Triatoma infestans Trypanosoma cruzi trypanosomiasis Animals Antibodies, Protozoan Argentina Blood Proteins Chagas Disease Cross-Sectional Studies Dog Diseases Dogs Ectoparasitic Infestations Female Hematocrit Insect Vectors Male Nutrition Disorders Nutritional Status Skinfold Thickness Survival Rate Triatoma Trypanosoma cruzi Animalia Canis familiaris Protozoa Triatoma infestans Trypanosoma Trypanosoma cruzi The association between the nutritional state of mongrel dogs naturally infected with Trypanosoma cruzi and their infectivity to Triatoma infestans bugs and immune response to Trypanosoma cruzi were studied in the rural village of Amamá, northwestern Argentina. All of the 97 evaluated dogs were classified into one of three categories of external clinical aspect (ECA) based on the degree of muscle development, external evidence of bone structures, state of the hair of the coat, existence of fatty deposits, and facial expression. ECA was significantly associated with two nutritional indicators, hematocrit and skin-fold thickness, but not with total serum proteins. For all dogs, hematocrit was significantly correlated with skin-fold thickness. The 2-year survival probability decreased significantly from 60.7% for dogs with good ECA to 45.9% and 31.2% for those with regular and bad ECA, respectively. The age-adjusted relative odds of infection for Triatoma infestans xenodiagnosis nymphs that fed once on a dog seroreactive for Trypanosoma cruzi decreased significantly as ECA improved, when tested by multiple logistic regression analysis. A delayed hypersensitivity reaction was observed in all of the seroreactive dogs with good ECA but only in 45-50% of those with regular or bad ECA. Dogs with bad ECA had a 2.6 and 6.3 times greater probability of infecting triatomines after a single full blood meal than dogs with regular or good ECA, respectively. Our study shows that the reservoir competence of dogs for Trypanosoma cruzi was associated with ECA, which is a surrogate and valid index of nutritional state. Fil:Gürtler, R.E. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Cecere, M.C. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Rubel, D.N. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Lauricella, M.A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Hansen, D. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 2001 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09320113_v87_n3_p208_Petersen http://hdl.handle.net/20.500.12110/paper_09320113_v87_n3_p208_Petersen
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic animal experiment
animal tissue
article
bone structure
facial expression
hematocrit
immune response
intermediate host
muscle development
nonhuman
nutritional status
parasite virulence
pathogenesis
priority journal
reservoir
serology
skinfold thickness
survival
Triatoma infestans
Trypanosoma cruzi
trypanosomiasis
Animals
Antibodies, Protozoan
Argentina
Blood Proteins
Chagas Disease
Cross-Sectional Studies
Dog Diseases
Dogs
Ectoparasitic Infestations
Female
Hematocrit
Insect Vectors
Male
Nutrition Disorders
Nutritional Status
Skinfold Thickness
Survival Rate
Triatoma
Trypanosoma cruzi
Animalia
Canis familiaris
Protozoa
Triatoma infestans
Trypanosoma
Trypanosoma cruzi
spellingShingle animal experiment
animal tissue
article
bone structure
facial expression
hematocrit
immune response
intermediate host
muscle development
nonhuman
nutritional status
parasite virulence
pathogenesis
priority journal
reservoir
serology
skinfold thickness
survival
Triatoma infestans
Trypanosoma cruzi
trypanosomiasis
Animals
Antibodies, Protozoan
Argentina
Blood Proteins
Chagas Disease
Cross-Sectional Studies
Dog Diseases
Dogs
Ectoparasitic Infestations
Female
Hematocrit
Insect Vectors
Male
Nutrition Disorders
Nutritional Status
Skinfold Thickness
Survival Rate
Triatoma
Trypanosoma cruzi
Animalia
Canis familiaris
Protozoa
Triatoma infestans
Trypanosoma
Trypanosoma cruzi
Gurtler, Ricardo Esteban
Cecere, Maria Carla
Rubel, Diana Nora
Lauricella, Marta Alicia
Hansen, Diana Silvia
Association between nutritional indicators and infectivity of dogs seroreactive for Trypanosoma cruzi in a rural area of northwestern Argentina
topic_facet animal experiment
animal tissue
article
bone structure
facial expression
hematocrit
immune response
intermediate host
muscle development
nonhuman
nutritional status
parasite virulence
pathogenesis
priority journal
reservoir
serology
skinfold thickness
survival
Triatoma infestans
Trypanosoma cruzi
trypanosomiasis
Animals
Antibodies, Protozoan
Argentina
Blood Proteins
Chagas Disease
Cross-Sectional Studies
Dog Diseases
Dogs
Ectoparasitic Infestations
Female
Hematocrit
Insect Vectors
Male
Nutrition Disorders
Nutritional Status
Skinfold Thickness
Survival Rate
Triatoma
Trypanosoma cruzi
Animalia
Canis familiaris
Protozoa
Triatoma infestans
Trypanosoma
Trypanosoma cruzi
description The association between the nutritional state of mongrel dogs naturally infected with Trypanosoma cruzi and their infectivity to Triatoma infestans bugs and immune response to Trypanosoma cruzi were studied in the rural village of Amamá, northwestern Argentina. All of the 97 evaluated dogs were classified into one of three categories of external clinical aspect (ECA) based on the degree of muscle development, external evidence of bone structures, state of the hair of the coat, existence of fatty deposits, and facial expression. ECA was significantly associated with two nutritional indicators, hematocrit and skin-fold thickness, but not with total serum proteins. For all dogs, hematocrit was significantly correlated with skin-fold thickness. The 2-year survival probability decreased significantly from 60.7% for dogs with good ECA to 45.9% and 31.2% for those with regular and bad ECA, respectively. The age-adjusted relative odds of infection for Triatoma infestans xenodiagnosis nymphs that fed once on a dog seroreactive for Trypanosoma cruzi decreased significantly as ECA improved, when tested by multiple logistic regression analysis. A delayed hypersensitivity reaction was observed in all of the seroreactive dogs with good ECA but only in 45-50% of those with regular or bad ECA. Dogs with bad ECA had a 2.6 and 6.3 times greater probability of infecting triatomines after a single full blood meal than dogs with regular or good ECA, respectively. Our study shows that the reservoir competence of dogs for Trypanosoma cruzi was associated with ECA, which is a surrogate and valid index of nutritional state.
author Gurtler, Ricardo Esteban
Cecere, Maria Carla
Rubel, Diana Nora
Lauricella, Marta Alicia
Hansen, Diana Silvia
author_facet Gurtler, Ricardo Esteban
Cecere, Maria Carla
Rubel, Diana Nora
Lauricella, Marta Alicia
Hansen, Diana Silvia
author_sort Gurtler, Ricardo Esteban
title Association between nutritional indicators and infectivity of dogs seroreactive for Trypanosoma cruzi in a rural area of northwestern Argentina
title_short Association between nutritional indicators and infectivity of dogs seroreactive for Trypanosoma cruzi in a rural area of northwestern Argentina
title_full Association between nutritional indicators and infectivity of dogs seroreactive for Trypanosoma cruzi in a rural area of northwestern Argentina
title_fullStr Association between nutritional indicators and infectivity of dogs seroreactive for Trypanosoma cruzi in a rural area of northwestern Argentina
title_full_unstemmed Association between nutritional indicators and infectivity of dogs seroreactive for Trypanosoma cruzi in a rural area of northwestern Argentina
title_sort association between nutritional indicators and infectivity of dogs seroreactive for trypanosoma cruzi in a rural area of northwestern argentina
publishDate 2001
url https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09320113_v87_n3_p208_Petersen
http://hdl.handle.net/20.500.12110/paper_09320113_v87_n3_p208_Petersen
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