Mass transport effect of mesoscopic domains in the amperometric response of an electroactive species: Modeling for its applications in biomolecule detection

We report the numerical simulation of an electrochemical system compromising a mesoporous material placed at a close distance of a working electrode. The effect of mesoscopic domains to the amperometric response of an electroactive species by applying a cyclic voltammetry is simulated to establish t...

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Autores principales:	Gonzalez, Graciela Alicia, Priano, Graciela Inés, Battaglini, Fernando
Publicado:	2010
Materias:	Amperometry Digital simulation Label-free sensing Mesoporous membrane Alumina membranes Amperometric response Biomolecule detection Close distance Electroactive species Electrochemical systems Horse-radish peroxidase Label free Mass transport Mesoporous membranes Mesoscopics Model system Numerical simulation Protein concentrations Reproducible behavior Working electrode Computer simulation Cyclic voltammetry Labels Mesoporous materials Optical devices Superconducting materials Mathematical models
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09254005_v144_n2_p349_Gonzalez http://hdl.handle.net/20.500.12110/paper_09254005_v144_n2_p349_Gonzalez
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	paper:paper_09254005_v144_n2_p349_Gonzalez
record_format	dspace
spelling	paper:paper_09254005_v144_n2_p349_Gonzalez2023-06-08T15:51:15Z Mass transport effect of mesoscopic domains in the amperometric response of an electroactive species: Modeling for its applications in biomolecule detection Gonzalez, Graciela Alicia Priano, Graciela Inés Battaglini, Fernando Amperometry Digital simulation Label-free sensing Mesoporous membrane Alumina membranes Amperometric response Amperometry Biomolecule detection Close distance Digital simulation Electroactive species Electrochemical systems Horse-radish peroxidase Label free Label-free sensing Mass transport Mesoporous membranes Mesoscopics Model system Numerical simulation Protein concentrations Reproducible behavior Working electrode Computer simulation Cyclic voltammetry Labels Mesoporous materials Optical devices Superconducting materials Mathematical models We report the numerical simulation of an electrochemical system compromising a mesoporous material placed at a close distance of a working electrode. The effect of mesoscopic domains to the amperometric response of an electroactive species by applying a cyclic voltammetry is simulated to establish the influence of different parameters on the sensitivity of this system to detect molecules able to block the pores. Alumina membranes were chosen as mesoporous material; they were modified with anti-horseradish peroxidase as model system to test the behavior predicted by the simulation. The label-free assembled electrochemical system shows a reproducible behavior and it is able to detect a 10 nM protein concentration. © 2008 Elsevier B.V. All rights reserved. Fil:González, G. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Priano, G. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Battaglini, F. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 2010 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09254005_v144_n2_p349_Gonzalez http://hdl.handle.net/20.500.12110/paper_09254005_v144_n2_p349_Gonzalez
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	Amperometry Digital simulation Label-free sensing Mesoporous membrane Alumina membranes Amperometric response Amperometry Biomolecule detection Close distance Digital simulation Electroactive species Electrochemical systems Horse-radish peroxidase Label free Label-free sensing Mass transport Mesoporous membranes Mesoscopics Model system Numerical simulation Protein concentrations Reproducible behavior Working electrode Computer simulation Cyclic voltammetry Labels Mesoporous materials Optical devices Superconducting materials Mathematical models
spellingShingle	Amperometry Digital simulation Label-free sensing Mesoporous membrane Alumina membranes Amperometric response Amperometry Biomolecule detection Close distance Digital simulation Electroactive species Electrochemical systems Horse-radish peroxidase Label free Label-free sensing Mass transport Mesoporous membranes Mesoscopics Model system Numerical simulation Protein concentrations Reproducible behavior Working electrode Computer simulation Cyclic voltammetry Labels Mesoporous materials Optical devices Superconducting materials Mathematical models Gonzalez, Graciela Alicia Priano, Graciela Inés Battaglini, Fernando Mass transport effect of mesoscopic domains in the amperometric response of an electroactive species: Modeling for its applications in biomolecule detection
topic_facet	Amperometry Digital simulation Label-free sensing Mesoporous membrane Alumina membranes Amperometric response Amperometry Biomolecule detection Close distance Digital simulation Electroactive species Electrochemical systems Horse-radish peroxidase Label free Label-free sensing Mass transport Mesoporous membranes Mesoscopics Model system Numerical simulation Protein concentrations Reproducible behavior Working electrode Computer simulation Cyclic voltammetry Labels Mesoporous materials Optical devices Superconducting materials Mathematical models
description	We report the numerical simulation of an electrochemical system compromising a mesoporous material placed at a close distance of a working electrode. The effect of mesoscopic domains to the amperometric response of an electroactive species by applying a cyclic voltammetry is simulated to establish the influence of different parameters on the sensitivity of this system to detect molecules able to block the pores. Alumina membranes were chosen as mesoporous material; they were modified with anti-horseradish peroxidase as model system to test the behavior predicted by the simulation. The label-free assembled electrochemical system shows a reproducible behavior and it is able to detect a 10 nM protein concentration. © 2008 Elsevier B.V. All rights reserved.
author	Gonzalez, Graciela Alicia Priano, Graciela Inés Battaglini, Fernando
author_facet	Gonzalez, Graciela Alicia Priano, Graciela Inés Battaglini, Fernando
author_sort	Gonzalez, Graciela Alicia
title	Mass transport effect of mesoscopic domains in the amperometric response of an electroactive species: Modeling for its applications in biomolecule detection
title_short	Mass transport effect of mesoscopic domains in the amperometric response of an electroactive species: Modeling for its applications in biomolecule detection
title_full	Mass transport effect of mesoscopic domains in the amperometric response of an electroactive species: Modeling for its applications in biomolecule detection
title_fullStr	Mass transport effect of mesoscopic domains in the amperometric response of an electroactive species: Modeling for its applications in biomolecule detection
title_full_unstemmed	Mass transport effect of mesoscopic domains in the amperometric response of an electroactive species: Modeling for its applications in biomolecule detection
title_sort	mass transport effect of mesoscopic domains in the amperometric response of an electroactive species: modeling for its applications in biomolecule detection
publishDate	2010
url	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09254005_v144_n2_p349_Gonzalez http://hdl.handle.net/20.500.12110/paper_09254005_v144_n2_p349_Gonzalez
work_keys_str_mv	AT gonzalezgracielaalicia masstransporteffectofmesoscopicdomainsintheamperometricresponseofanelectroactivespeciesmodelingforitsapplicationsinbiomoleculedetection AT prianogracielaines masstransporteffectofmesoscopicdomainsintheamperometricresponseofanelectroactivespeciesmodelingforitsapplicationsinbiomoleculedetection AT battaglinifernando masstransporteffectofmesoscopicdomainsintheamperometricresponseofanelectroactivespeciesmodelingforitsapplicationsinbiomoleculedetection
_version_	1768542042385809408

Mass transport effect of mesoscopic domains in the amperometric response of an electroactive species: Modeling for its applications in biomolecule detection

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