Antiherpetic mode of action of (22S,23S)-3β-bromo-5α,22,23- trihydroxystigmastan-6-one in vitro

The replication of herpes simplex virus (HSV) type 1 in Vero cells is inhibited in the presence of (22S,23S)-3β-bromo-5α,22,23- trihydroxystigmastan-6-one (6b), a synthetic brassinosteroid derivative. Attempts to disclose the mode of action of 6b indicate that a late step of virus multiplication is...

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Detalles Bibliográficos
Autores principales: Wachsman, Mónica Beatriz, Castilla, Viviana, Talarico, Laura Beatriz, Ramirez, Javier Alberto, Coto, Celia Esther
Publicado: 2004
Materias:
(22S,23S)-3β- Bromo-5α,22,23-trihydroxystigmastan-6-one
Antiviral
Brassinosteroid derivatives
Herpes simplex
3beta bromo 5alpha,22,23 trihydroxystigmastan 6 one
antivirus agent
brassinosteroid
unclassified drug
animal cell
antigen expression
article
controlled study
drug mechanism
Herpes simplex virus 1
immunofluorescence test
in vitro study
nonhuman
priority journal
protein synthesis
Vero cell
virus replication
Animals
Antigens, Viral
Antiviral Agents
Cercopithecus aethiops
Cholestanones
Fluorescent Antibody Technique, Indirect
Herpesvirus 1, Human
Transcription, Genetic
Vero Cells
Viral Proteins
Virus Replication
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09248579_v23_n5_p524_Wachsman
http://hdl.handle.net/20.500.12110/paper_09248579_v23_n5_p524_Wachsman
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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