Cortisol: A tool to study aldosterone biosynthesis in rats
Corticosterone (B) and 18-hydroxy-11-deoxycorticosterone (18OHDOC) but not 11-deoxycorticosterone (DOC) displaced cortisol (F) specifically bound to rat adrenal mitochondria. F competitively inhibited aldosterone formation from B, 18OHB and 18OHDOC but did not inhibit conversions of DOC to B or 18OH...
Guardado en:
| Publicado: |
1995
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| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_07435800_v21_n1-2_p471_Matković http://hdl.handle.net/20.500.12110/paper_07435800_v21_n1-2_p471_Matković |
| Aporte de: |
| id |
paper:paper_07435800_v21_n1-2_p471_MatkoviÃÂ |
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| record_format |
dspace |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
18 hydroxydeoxycorticosterone aldosterone corticosterone cytochrome p450 deoxycorticosterone hydrocortisone steroid 11beta monooxygenase adrenal cortex animal tissue conference paper controlled study enzyme activity enzyme substrate male mitochondrion nonhuman priority journal rat steroidogenesis 18-Hydroxydesoxycorticosterone Adrenal Glands Aldosterone Animal Binding, Competitive Corticosterone Hydrocortisone Male Mitochondria Rats Rats, Inbred Strains Support, Non-U.S. Gov't Support, U.S. Gov't, P.H.S. |
| spellingShingle |
18 hydroxydeoxycorticosterone aldosterone corticosterone cytochrome p450 deoxycorticosterone hydrocortisone steroid 11beta monooxygenase adrenal cortex animal tissue conference paper controlled study enzyme activity enzyme substrate male mitochondrion nonhuman priority journal rat steroidogenesis 18-Hydroxydesoxycorticosterone Adrenal Glands Aldosterone Animal Binding, Competitive Corticosterone Hydrocortisone Male Mitochondria Rats Rats, Inbred Strains Support, Non-U.S. Gov't Support, U.S. Gov't, P.H.S. Cortisol: A tool to study aldosterone biosynthesis in rats |
| topic_facet |
18 hydroxydeoxycorticosterone aldosterone corticosterone cytochrome p450 deoxycorticosterone hydrocortisone steroid 11beta monooxygenase adrenal cortex animal tissue conference paper controlled study enzyme activity enzyme substrate male mitochondrion nonhuman priority journal rat steroidogenesis 18-Hydroxydesoxycorticosterone Adrenal Glands Aldosterone Animal Binding, Competitive Corticosterone Hydrocortisone Male Mitochondria Rats Rats, Inbred Strains Support, Non-U.S. Gov't Support, U.S. Gov't, P.H.S. |
| description |
Corticosterone (B) and 18-hydroxy-11-deoxycorticosterone (18OHDOC) but not 11-deoxycorticosterone (DOC) displaced cortisol (F) specifically bound to rat adrenal mitochondria. F competitively inhibited aldosterone formation from B, 18OHB and 18OHDOC but did not inhibit conversions of DOC to B or 18OHDOC. High concentrations of DOC increased its conversion to 18OHDOC rather than B. © 1995 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted. |
| title |
Cortisol: A tool to study aldosterone biosynthesis in rats |
| title_short |
Cortisol: A tool to study aldosterone biosynthesis in rats |
| title_full |
Cortisol: A tool to study aldosterone biosynthesis in rats |
| title_fullStr |
Cortisol: A tool to study aldosterone biosynthesis in rats |
| title_full_unstemmed |
Cortisol: A tool to study aldosterone biosynthesis in rats |
| title_sort |
cortisol: a tool to study aldosterone biosynthesis in rats |
| publishDate |
1995 |
| url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_07435800_v21_n1-2_p471_Matković http://hdl.handle.net/20.500.12110/paper_07435800_v21_n1-2_p471_Matković |
| bdutipo_str |
Repositorios |
| _version_ |
1764820563297042432 |