Relevance of apoptosis in the female reproductive system
Apoptosis is a genetically controlled form of cell suicide. Due to the cyclic nature of the female reproductive system, the ovary, the endometrium and the mammary gland sustain continuous cycles of cell growth and apoptosis in response to hormonal changes. Apoptotic cell death plays multiple roles d...
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2011
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| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_05355133_v52_n3_p274_Meresman http://hdl.handle.net/20.500.12110/paper_05355133_v52_n3_p274_Meresman |
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paper:paper_05355133_v52_n3_p274_Meresman2023-06-08T15:41:14Z Relevance of apoptosis in the female reproductive system Apoptosis Endometriosis Endometrium Mammary gland Ovary apoptosis regulatory protein sex hormone animal apoptosis breast Caenorhabditis elegans corpus luteum cytology embryo development endometriosis epithelium cell female female genital system female genital tract tumor human lactation menstrual cycle metabolism morphogenesis ovary follicle ovulation pathology physiology pregnancy prenatal development puberty review ultrastructure article cell growth endometrium endometrium cancer mammary gland organogenesis ovary ovary follicle development Animals Apoptosis Apoptosis Regulatory Proteins Breast Caenorhabditis elegans Corpus Luteum Embryonic Development Endometriosis Epithelial Cells Female Genital Neoplasms, Female Genitalia, Female Gonadal Steroid Hormones Humans Lactation Menstrual Cycle Morphogenesis Ovarian Follicle Ovulation Pregnancy Puberty Apoptosis is a genetically controlled form of cell suicide. Due to the cyclic nature of the female reproductive system, the ovary, the endometrium and the mammary gland sustain continuous cycles of cell growth and apoptosis in response to hormonal changes. Apoptotic cell death plays multiple roles during embryonic and organ development. It is involved in sculpturing tissues and serves to delete structures that are no longer required. It is clear that apoptosis plays an active and important role in ovarian physiological functions. Apoptosis plays a major role during folliculogenesis and dominant follicle selection and also plays part in corpus luteum regression. In addition, it has been shown that programmed cell death plays important roles in the mammary gland development and ductal morphogenesis. During puberty, lumen formation is associated with the selective apoptosis of centrally located cells. In turn, postlactational involution of the mammary gland is characterized by the secretory epithelial cells undergoing programmed cell death. Apoptosis has also been associated with physiological, as well as pathological, endometrial processes such as cancer and endometriosis. The delicate balance between apoptosis and cell proliferation is essential in controlling the cyclical growth of the reproductive tissues and plays an important role in the prevention of neoplastic transformation. 2011 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_05355133_v52_n3_p274_Meresman http://hdl.handle.net/20.500.12110/paper_05355133_v52_n3_p274_Meresman |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Apoptosis Endometriosis Endometrium Mammary gland Ovary apoptosis regulatory protein sex hormone animal apoptosis breast Caenorhabditis elegans corpus luteum cytology embryo development endometriosis epithelium cell female female genital system female genital tract tumor human lactation menstrual cycle metabolism morphogenesis ovary follicle ovulation pathology physiology pregnancy prenatal development puberty review ultrastructure article cell growth endometrium endometrium cancer mammary gland organogenesis ovary ovary follicle development Animals Apoptosis Apoptosis Regulatory Proteins Breast Caenorhabditis elegans Corpus Luteum Embryonic Development Endometriosis Epithelial Cells Female Genital Neoplasms, Female Genitalia, Female Gonadal Steroid Hormones Humans Lactation Menstrual Cycle Morphogenesis Ovarian Follicle Ovulation Pregnancy Puberty |
| spellingShingle |
Apoptosis Endometriosis Endometrium Mammary gland Ovary apoptosis regulatory protein sex hormone animal apoptosis breast Caenorhabditis elegans corpus luteum cytology embryo development endometriosis epithelium cell female female genital system female genital tract tumor human lactation menstrual cycle metabolism morphogenesis ovary follicle ovulation pathology physiology pregnancy prenatal development puberty review ultrastructure article cell growth endometrium endometrium cancer mammary gland organogenesis ovary ovary follicle development Animals Apoptosis Apoptosis Regulatory Proteins Breast Caenorhabditis elegans Corpus Luteum Embryonic Development Endometriosis Epithelial Cells Female Genital Neoplasms, Female Genitalia, Female Gonadal Steroid Hormones Humans Lactation Menstrual Cycle Morphogenesis Ovarian Follicle Ovulation Pregnancy Puberty Relevance of apoptosis in the female reproductive system |
| topic_facet |
Apoptosis Endometriosis Endometrium Mammary gland Ovary apoptosis regulatory protein sex hormone animal apoptosis breast Caenorhabditis elegans corpus luteum cytology embryo development endometriosis epithelium cell female female genital system female genital tract tumor human lactation menstrual cycle metabolism morphogenesis ovary follicle ovulation pathology physiology pregnancy prenatal development puberty review ultrastructure article cell growth endometrium endometrium cancer mammary gland organogenesis ovary ovary follicle development Animals Apoptosis Apoptosis Regulatory Proteins Breast Caenorhabditis elegans Corpus Luteum Embryonic Development Endometriosis Epithelial Cells Female Genital Neoplasms, Female Genitalia, Female Gonadal Steroid Hormones Humans Lactation Menstrual Cycle Morphogenesis Ovarian Follicle Ovulation Pregnancy Puberty |
| description |
Apoptosis is a genetically controlled form of cell suicide. Due to the cyclic nature of the female reproductive system, the ovary, the endometrium and the mammary gland sustain continuous cycles of cell growth and apoptosis in response to hormonal changes. Apoptotic cell death plays multiple roles during embryonic and organ development. It is involved in sculpturing tissues and serves to delete structures that are no longer required. It is clear that apoptosis plays an active and important role in ovarian physiological functions. Apoptosis plays a major role during folliculogenesis and dominant follicle selection and also plays part in corpus luteum regression. In addition, it has been shown that programmed cell death plays important roles in the mammary gland development and ductal morphogenesis. During puberty, lumen formation is associated with the selective apoptosis of centrally located cells. In turn, postlactational involution of the mammary gland is characterized by the secretory epithelial cells undergoing programmed cell death. Apoptosis has also been associated with physiological, as well as pathological, endometrial processes such as cancer and endometriosis. The delicate balance between apoptosis and cell proliferation is essential in controlling the cyclical growth of the reproductive tissues and plays an important role in the prevention of neoplastic transformation. |
| title |
Relevance of apoptosis in the female reproductive system |
| title_short |
Relevance of apoptosis in the female reproductive system |
| title_full |
Relevance of apoptosis in the female reproductive system |
| title_fullStr |
Relevance of apoptosis in the female reproductive system |
| title_full_unstemmed |
Relevance of apoptosis in the female reproductive system |
| title_sort |
relevance of apoptosis in the female reproductive system |
| publishDate |
2011 |
| url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_05355133_v52_n3_p274_Meresman http://hdl.handle.net/20.500.12110/paper_05355133_v52_n3_p274_Meresman |
| _version_ |
1768542992430268416 |