Perspectives for the Therapy against Arenavirus Infections

Five arenaviruses are able to cause severe hemorrhagic fevers (HF) in humans, and two of them, Lassa virus and Junin virus generate periodic annual outbreaks of severe hemorrhagic fever with high mortality rate in West Africa and Argentina, respectively. This chapter describes the drawbacks of the p...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Damonte, Elsa Beatriz, García, Cybele Carina
Publicado:	2005
Materias:	Antiviral therapy Arenavirus Assembly Budding Hemorrhagic fever Junin Virus Lassa Virus Replicative cycle Virus entry Virus maturation
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_04716682_v_n_p115_Damonte http://hdl.handle.net/20.500.12110/paper_04716682_v_n_p115_Damonte
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	paper:paper_04716682_v_n_p115_Damonte
record_format	dspace
spelling	paper:paper_04716682_v_n_p115_Damonte2023-06-08T15:41:10Z Perspectives for the Therapy against Arenavirus Infections Damonte, Elsa Beatriz García, Cybele Carina Antiviral therapy Arenavirus Assembly Budding Hemorrhagic fever Junin Virus Lassa Virus Replicative cycle Virus entry Virus maturation Five arenaviruses are able to cause severe hemorrhagic fevers (HF) in humans, and two of them, Lassa virus and Junin virus generate periodic annual outbreaks of severe hemorrhagic fever with high mortality rate in West Africa and Argentina, respectively. This chapter describes the drawbacks of the present treatment of arenavirus HF, mainly based on the administration of immune plasma or the drug ribavirin, and the future perspectives for therapy, mainly focused on new possible targets in early and late stages of the replicative cycle, responsible of viral entry to the cell and virus maturation, assembly and budding, respectively. © 2005 John Wiley & Sons, Inc. Fil:Damonte, E.B. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:García, C.C. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 2005 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_04716682_v_n_p115_Damonte http://hdl.handle.net/20.500.12110/paper_04716682_v_n_p115_Damonte
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	Antiviral therapy Arenavirus Assembly Budding Hemorrhagic fever Junin Virus Lassa Virus Replicative cycle Virus entry Virus maturation
spellingShingle	Antiviral therapy Arenavirus Assembly Budding Hemorrhagic fever Junin Virus Lassa Virus Replicative cycle Virus entry Virus maturation Damonte, Elsa Beatriz García, Cybele Carina Perspectives for the Therapy against Arenavirus Infections
topic_facet	Antiviral therapy Arenavirus Assembly Budding Hemorrhagic fever Junin Virus Lassa Virus Replicative cycle Virus entry Virus maturation
description	Five arenaviruses are able to cause severe hemorrhagic fevers (HF) in humans, and two of them, Lassa virus and Junin virus generate periodic annual outbreaks of severe hemorrhagic fever with high mortality rate in West Africa and Argentina, respectively. This chapter describes the drawbacks of the present treatment of arenavirus HF, mainly based on the administration of immune plasma or the drug ribavirin, and the future perspectives for therapy, mainly focused on new possible targets in early and late stages of the replicative cycle, responsible of viral entry to the cell and virus maturation, assembly and budding, respectively. © 2005 John Wiley & Sons, Inc.
author	Damonte, Elsa Beatriz García, Cybele Carina
author_facet	Damonte, Elsa Beatriz García, Cybele Carina
author_sort	Damonte, Elsa Beatriz
title	Perspectives for the Therapy against Arenavirus Infections
title_short	Perspectives for the Therapy against Arenavirus Infections
title_full	Perspectives for the Therapy against Arenavirus Infections
title_fullStr	Perspectives for the Therapy against Arenavirus Infections
title_full_unstemmed	Perspectives for the Therapy against Arenavirus Infections
title_sort	perspectives for the therapy against arenavirus infections
publishDate	2005
url	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_04716682_v_n_p115_Damonte http://hdl.handle.net/20.500.12110/paper_04716682_v_n_p115_Damonte
work_keys_str_mv	AT damonteelsabeatriz perspectivesforthetherapyagainstarenavirusinfections AT garciacybelecarina perspectivesforthetherapyagainstarenavirusinfections
_version_	1768544137218359296

Perspectives for the Therapy against Arenavirus Infections

Ejemplares similares