Iodination, radioiodination and spectroscopic identification of β-carboline derivatives

The synthesis and spectral properties (MS, and NMR) of radioiodinated β-carbolines: 6-(I) and 8-(II) [131I]-iodo-1-methyl-7-methoxy-β-carboline ([131I]-iodo-harmine), 6-(III) and 8-(IV) [131I]-iodo-1-methyl-β-carboline-7-ol([131I]-iodo-harmol), 8-[131I]-iodo-1-methyl-7-methoxy-3,4-dihydro-β-carbolin...

Descripción completa

Detalles Bibliográficos
Publicado: 1999
Materias:
[131I]-iodo-β-carbolines
Preparation and characterization
amine oxidase (flavin containing)
beta carboline derivative
harmine
article
brain mapping
human
iodination
mass spectrometry
nuclear magnetic resonance spectroscopy
radioiodination
single photon emission computer tomography
synthesis
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03624803_v42_n5_p409_Sintas
http://hdl.handle.net/20.500.12110/paper_03624803_v42_n5_p409_Sintas
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
id paper:paper_03624803_v42_n5_p409_Sintas
record_format dspace
spelling paper:paper_03624803_v42_n5_p409_Sintas2023-06-08T15:35:12Z Iodination, radioiodination and spectroscopic identification of β-carboline derivatives [131I]-iodo-β-carbolines Preparation and characterization amine oxidase (flavin containing) beta carboline derivative harmine article brain mapping human iodination mass spectrometry nuclear magnetic resonance spectroscopy radioiodination single photon emission computer tomography synthesis The synthesis and spectral properties (MS, and NMR) of radioiodinated β-carbolines: 6-(I) and 8-(II) [131I]-iodo-1-methyl-7-methoxy-β-carboline ([131I]-iodo-harmine), 6-(III) and 8-(IV) [131I]-iodo-1-methyl-β-carboline-7-ol([131I]-iodo-harmol), 8-[131I]-iodo-1-methyl-7-methoxy-3,4-dihydro-β-carboline (8-[131I]-iodo-harmaline) (V), 8-[131I]-iodo-3,4-dihydro-1-methyl-β-carboline-7-ol (8-[131I]-iodo-harmalol) (VI), 6-[131I]-iodo-1-methyl-β-carboline (6-[131I]-iodo-harmane) (VII) are described. These are compounds of biological importance and can be used for brain mapping with SPECT technology. 1999 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03624803_v42_n5_p409_Sintas http://hdl.handle.net/20.500.12110/paper_03624803_v42_n5_p409_Sintas
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic [131I]-iodo-β-carbolines
Preparation and characterization
amine oxidase (flavin containing)
beta carboline derivative
harmine
article
brain mapping
human
iodination
mass spectrometry
nuclear magnetic resonance spectroscopy
radioiodination
single photon emission computer tomography
synthesis
spellingShingle [131I]-iodo-β-carbolines
Preparation and characterization
amine oxidase (flavin containing)
beta carboline derivative
harmine
article
brain mapping
human
iodination
mass spectrometry
nuclear magnetic resonance spectroscopy
radioiodination
single photon emission computer tomography
synthesis
Iodination, radioiodination and spectroscopic identification of β-carboline derivatives
topic_facet [131I]-iodo-β-carbolines
Preparation and characterization
amine oxidase (flavin containing)
beta carboline derivative
harmine
article
brain mapping
human
iodination
mass spectrometry
nuclear magnetic resonance spectroscopy
radioiodination
single photon emission computer tomography
synthesis
description The synthesis and spectral properties (MS, and NMR) of radioiodinated β-carbolines: 6-(I) and 8-(II) [131I]-iodo-1-methyl-7-methoxy-β-carboline ([131I]-iodo-harmine), 6-(III) and 8-(IV) [131I]-iodo-1-methyl-β-carboline-7-ol([131I]-iodo-harmol), 8-[131I]-iodo-1-methyl-7-methoxy-3,4-dihydro-β-carboline (8-[131I]-iodo-harmaline) (V), 8-[131I]-iodo-3,4-dihydro-1-methyl-β-carboline-7-ol (8-[131I]-iodo-harmalol) (VI), 6-[131I]-iodo-1-methyl-β-carboline (6-[131I]-iodo-harmane) (VII) are described. These are compounds of biological importance and can be used for brain mapping with SPECT technology.
title Iodination, radioiodination and spectroscopic identification of β-carboline derivatives
title_short Iodination, radioiodination and spectroscopic identification of β-carboline derivatives
title_full Iodination, radioiodination and spectroscopic identification of β-carboline derivatives
title_fullStr Iodination, radioiodination and spectroscopic identification of β-carboline derivatives
title_full_unstemmed Iodination, radioiodination and spectroscopic identification of β-carboline derivatives
title_sort iodination, radioiodination and spectroscopic identification of β-carboline derivatives
publishDate 1999
url https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03624803_v42_n5_p409_Sintas
http://hdl.handle.net/20.500.12110/paper_03624803_v42_n5_p409_Sintas
_version_ 1768543470698364928

Ejemplares similares