Synthesis of 131I derivatives of indolealkylamines for brain mapping
The synthesis and spectral properties of new radioiodinated indolealkylamines like 2-[131 I]-iodo-N,N-dimethyltryptamine, 2-[131 I]-iodo-N-methyltryptamine, 2-[131 I]-iodo-5-methoxy-N,N-dimethyltryptamine, 2-[131 I]-iodo-5-hydroxy-N,N-dimethyltryptamine (2-[131 I]-iodo-bufotenine), and 2-[131I]-iodo...
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1997
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Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03624803_v39_n8_p677_Sintas http://hdl.handle.net/20.500.12110/paper_03624803_v39_n8_p677_Sintas |
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paper:paper_03624803_v39_n8_p677_Sintas2023-06-08T15:35:12Z Synthesis of 131I derivatives of indolealkylamines for brain mapping Vitale, Arturo Alberto 2-[131I]-iodo-5-hydroxy-N,N-dimethyltryptamine 2-[131I]-iodo-5-methoxy-N,N-dimethyltryptamine 2-[131I]-iodo-N,N-dimethyltryptamine 2-[131I]-iodo-N-methyltryptamine 2-[131I]-iodo-tryptamine 2-[131I]-melatonine indoleamine iodine 131 tryptamine derivative article brain mapping drug purity drug synthesis in vitro study iodination mass spectrometry nuclear magnetic resonance spectroscopy radiochemistry radioiodination reaction analysis The synthesis and spectral properties of new radioiodinated indolealkylamines like 2-[131 I]-iodo-N,N-dimethyltryptamine, 2-[131 I]-iodo-N-methyltryptamine, 2-[131 I]-iodo-5-methoxy-N,N-dimethyltryptamine, 2-[131 I]-iodo-5-hydroxy-N,N-dimethyltryptamine (2-[131 I]-iodo-bufotenine), and 2-[131I]-iodo-tryptamine and the known 2-[131I]-iodo-N-acetyl-5-methoxy-tryptamine (2-[131I]-iodo-melatonine) are described herein. These were synthesized by a high-yield novel method, and their spectral properties are fully described. These compounds are of biological importance and can be used for brain mapping with SPECT technology. Fil:Vitale, A.A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 1997 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03624803_v39_n8_p677_Sintas http://hdl.handle.net/20.500.12110/paper_03624803_v39_n8_p677_Sintas |
institution |
Universidad de Buenos Aires |
institution_str |
I-28 |
repository_str |
R-134 |
collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
topic |
2-[131I]-iodo-5-hydroxy-N,N-dimethyltryptamine 2-[131I]-iodo-5-methoxy-N,N-dimethyltryptamine 2-[131I]-iodo-N,N-dimethyltryptamine 2-[131I]-iodo-N-methyltryptamine 2-[131I]-iodo-tryptamine 2-[131I]-melatonine indoleamine iodine 131 tryptamine derivative article brain mapping drug purity drug synthesis in vitro study iodination mass spectrometry nuclear magnetic resonance spectroscopy radiochemistry radioiodination reaction analysis |
spellingShingle |
2-[131I]-iodo-5-hydroxy-N,N-dimethyltryptamine 2-[131I]-iodo-5-methoxy-N,N-dimethyltryptamine 2-[131I]-iodo-N,N-dimethyltryptamine 2-[131I]-iodo-N-methyltryptamine 2-[131I]-iodo-tryptamine 2-[131I]-melatonine indoleamine iodine 131 tryptamine derivative article brain mapping drug purity drug synthesis in vitro study iodination mass spectrometry nuclear magnetic resonance spectroscopy radiochemistry radioiodination reaction analysis Vitale, Arturo Alberto Synthesis of 131I derivatives of indolealkylamines for brain mapping |
topic_facet |
2-[131I]-iodo-5-hydroxy-N,N-dimethyltryptamine 2-[131I]-iodo-5-methoxy-N,N-dimethyltryptamine 2-[131I]-iodo-N,N-dimethyltryptamine 2-[131I]-iodo-N-methyltryptamine 2-[131I]-iodo-tryptamine 2-[131I]-melatonine indoleamine iodine 131 tryptamine derivative article brain mapping drug purity drug synthesis in vitro study iodination mass spectrometry nuclear magnetic resonance spectroscopy radiochemistry radioiodination reaction analysis |
description |
The synthesis and spectral properties of new radioiodinated indolealkylamines like 2-[131 I]-iodo-N,N-dimethyltryptamine, 2-[131 I]-iodo-N-methyltryptamine, 2-[131 I]-iodo-5-methoxy-N,N-dimethyltryptamine, 2-[131 I]-iodo-5-hydroxy-N,N-dimethyltryptamine (2-[131 I]-iodo-bufotenine), and 2-[131I]-iodo-tryptamine and the known 2-[131I]-iodo-N-acetyl-5-methoxy-tryptamine (2-[131I]-iodo-melatonine) are described herein. These were synthesized by a high-yield novel method, and their spectral properties are fully described. These compounds are of biological importance and can be used for brain mapping with SPECT technology. |
author |
Vitale, Arturo Alberto |
author_facet |
Vitale, Arturo Alberto |
author_sort |
Vitale, Arturo Alberto |
title |
Synthesis of 131I derivatives of indolealkylamines for brain mapping |
title_short |
Synthesis of 131I derivatives of indolealkylamines for brain mapping |
title_full |
Synthesis of 131I derivatives of indolealkylamines for brain mapping |
title_fullStr |
Synthesis of 131I derivatives of indolealkylamines for brain mapping |
title_full_unstemmed |
Synthesis of 131I derivatives of indolealkylamines for brain mapping |
title_sort |
synthesis of 131i derivatives of indolealkylamines for brain mapping |
publishDate |
1997 |
url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03624803_v39_n8_p677_Sintas http://hdl.handle.net/20.500.12110/paper_03624803_v39_n8_p677_Sintas |
work_keys_str_mv |
AT vitalearturoalberto synthesisof131iderivativesofindolealkylaminesforbrainmapping |
_version_ |
1768545881690210304 |