The activity of leech motoneurons during motor patterns is regulated by intrinsic properties and synaptic inputs
The activity of motoneurons during motor patterns depends on their intrinsic properties and on synaptic inputs. This study analyzed the properties of two leech motoneurons: the excitors of dorsal longitudinal muscles (DE-3) and of dorsal and ventral longitudinal muscles (MN-L) in basal conditions (n...
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Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03407594_v198_n3_p239_PerezEtchegoyen http://hdl.handle.net/20.500.12110/paper_03407594_v198_n3_p239_PerezEtchegoyen |
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paper:paper_03407594_v198_n3_p239_PerezEtchegoyen2023-06-08T15:34:26Z The activity of leech motoneurons during motor patterns is regulated by intrinsic properties and synaptic inputs Perez Etchegoyen, C. Bernardo Rodríguez, Mariano Julián Szczupak, Lidia Crawling Excitability Leech motoneuron Motor control Spike frequency adaptation animal article cell membrane potential leech motoneuron motor activity physiology synapse synaptic transmission Animals Leeches Membrane Potentials Motor Activity Motor Neurons Synapses Synaptic Transmission The activity of motoneurons during motor patterns depends on their intrinsic properties and on synaptic inputs. This study analyzed the properties of two leech motoneurons: the excitors of dorsal longitudinal muscles (DE-3) and of dorsal and ventral longitudinal muscles (MN-L) in basal conditions (normal and high Mg 2+ saline) and during crawling. The voltage-current relationships in DE-3 and MN-L were similar. The curves exhibited the largest slope around resting potential, showed marked inward and outward rectification, and were not affected by high Mg 2+. In response to 5-s pulses, DE-3 exhibited a fast initial adaptation, a slow recovery and a very slow late adaptation. High Mg 2+ abolished the initial high frequency. The frequency-voltage relationship for the rest of the response was highly similar in normal and in high Mg 2+ saline. MN-L exhibited a minor initial adaptation and then fired steadily. High Mg 2+ diminished the frequency-voltage relationship. During crawling DE-3 and MN-L fired in phase and their frequency-voltage curves overlapped with the lower end of the curves obtained in basal conditions. The results suggest that the activity of these motoneurons during crawling was regulated, to a large extent, by synaptic inputs. © 2011 Springer-Verlag. Fil:Perez-Etchegoyen, C.B. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Rodriguez, M.J. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Szczupak, L. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 2012 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03407594_v198_n3_p239_PerezEtchegoyen http://hdl.handle.net/20.500.12110/paper_03407594_v198_n3_p239_PerezEtchegoyen |
institution |
Universidad de Buenos Aires |
institution_str |
I-28 |
repository_str |
R-134 |
collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
topic |
Crawling Excitability Leech motoneuron Motor control Spike frequency adaptation animal article cell membrane potential leech motoneuron motor activity physiology synapse synaptic transmission Animals Leeches Membrane Potentials Motor Activity Motor Neurons Synapses Synaptic Transmission |
spellingShingle |
Crawling Excitability Leech motoneuron Motor control Spike frequency adaptation animal article cell membrane potential leech motoneuron motor activity physiology synapse synaptic transmission Animals Leeches Membrane Potentials Motor Activity Motor Neurons Synapses Synaptic Transmission Perez Etchegoyen, C. Bernardo Rodríguez, Mariano Julián Szczupak, Lidia The activity of leech motoneurons during motor patterns is regulated by intrinsic properties and synaptic inputs |
topic_facet |
Crawling Excitability Leech motoneuron Motor control Spike frequency adaptation animal article cell membrane potential leech motoneuron motor activity physiology synapse synaptic transmission Animals Leeches Membrane Potentials Motor Activity Motor Neurons Synapses Synaptic Transmission |
description |
The activity of motoneurons during motor patterns depends on their intrinsic properties and on synaptic inputs. This study analyzed the properties of two leech motoneurons: the excitors of dorsal longitudinal muscles (DE-3) and of dorsal and ventral longitudinal muscles (MN-L) in basal conditions (normal and high Mg 2+ saline) and during crawling. The voltage-current relationships in DE-3 and MN-L were similar. The curves exhibited the largest slope around resting potential, showed marked inward and outward rectification, and were not affected by high Mg 2+. In response to 5-s pulses, DE-3 exhibited a fast initial adaptation, a slow recovery and a very slow late adaptation. High Mg 2+ abolished the initial high frequency. The frequency-voltage relationship for the rest of the response was highly similar in normal and in high Mg 2+ saline. MN-L exhibited a minor initial adaptation and then fired steadily. High Mg 2+ diminished the frequency-voltage relationship. During crawling DE-3 and MN-L fired in phase and their frequency-voltage curves overlapped with the lower end of the curves obtained in basal conditions. The results suggest that the activity of these motoneurons during crawling was regulated, to a large extent, by synaptic inputs. © 2011 Springer-Verlag. |
author |
Perez Etchegoyen, C. Bernardo Rodríguez, Mariano Julián Szczupak, Lidia |
author_facet |
Perez Etchegoyen, C. Bernardo Rodríguez, Mariano Julián Szczupak, Lidia |
author_sort |
Perez Etchegoyen, C. Bernardo |
title |
The activity of leech motoneurons during motor patterns is regulated by intrinsic properties and synaptic inputs |
title_short |
The activity of leech motoneurons during motor patterns is regulated by intrinsic properties and synaptic inputs |
title_full |
The activity of leech motoneurons during motor patterns is regulated by intrinsic properties and synaptic inputs |
title_fullStr |
The activity of leech motoneurons during motor patterns is regulated by intrinsic properties and synaptic inputs |
title_full_unstemmed |
The activity of leech motoneurons during motor patterns is regulated by intrinsic properties and synaptic inputs |
title_sort |
activity of leech motoneurons during motor patterns is regulated by intrinsic properties and synaptic inputs |
publishDate |
2012 |
url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03407594_v198_n3_p239_PerezEtchegoyen http://hdl.handle.net/20.500.12110/paper_03407594_v198_n3_p239_PerezEtchegoyen |
work_keys_str_mv |
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