The activity of leech motoneurons during motor patterns is regulated by intrinsic properties and synaptic inputs

The activity of motoneurons during motor patterns depends on their intrinsic properties and on synaptic inputs. This study analyzed the properties of two leech motoneurons: the excitors of dorsal longitudinal muscles (DE-3) and of dorsal and ventral longitudinal muscles (MN-L) in basal conditions (n...

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Autores principales: Perez Etchegoyen, C. Bernardo, Rodríguez, Mariano Julián, Szczupak, Lidia
Publicado: 2012
Materias:
Crawling
Excitability
Leech motoneuron
Motor control
Spike frequency adaptation
animal
article
cell membrane potential
leech
motoneuron
motor activity
physiology
synapse
synaptic transmission
Animals
Leeches
Membrane Potentials
Motor Activity
Motor Neurons
Synapses
Synaptic Transmission
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03407594_v198_n3_p239_PerezEtchegoyen
http://hdl.handle.net/20.500.12110/paper_03407594_v198_n3_p239_PerezEtchegoyen
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Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
id paper:paper_03407594_v198_n3_p239_PerezEtchegoyen
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spelling paper:paper_03407594_v198_n3_p239_PerezEtchegoyen2023-06-08T15:34:26Z The activity of leech motoneurons during motor patterns is regulated by intrinsic properties and synaptic inputs Perez Etchegoyen, C. Bernardo Rodríguez, Mariano Julián Szczupak, Lidia Crawling Excitability Leech motoneuron Motor control Spike frequency adaptation animal article cell membrane potential leech motoneuron motor activity physiology synapse synaptic transmission Animals Leeches Membrane Potentials Motor Activity Motor Neurons Synapses Synaptic Transmission The activity of motoneurons during motor patterns depends on their intrinsic properties and on synaptic inputs. This study analyzed the properties of two leech motoneurons: the excitors of dorsal longitudinal muscles (DE-3) and of dorsal and ventral longitudinal muscles (MN-L) in basal conditions (normal and high Mg 2+ saline) and during crawling. The voltage-current relationships in DE-3 and MN-L were similar. The curves exhibited the largest slope around resting potential, showed marked inward and outward rectification, and were not affected by high Mg 2+. In response to 5-s pulses, DE-3 exhibited a fast initial adaptation, a slow recovery and a very slow late adaptation. High Mg 2+ abolished the initial high frequency. The frequency-voltage relationship for the rest of the response was highly similar in normal and in high Mg 2+ saline. MN-L exhibited a minor initial adaptation and then fired steadily. High Mg 2+ diminished the frequency-voltage relationship. During crawling DE-3 and MN-L fired in phase and their frequency-voltage curves overlapped with the lower end of the curves obtained in basal conditions. The results suggest that the activity of these motoneurons during crawling was regulated, to a large extent, by synaptic inputs. © 2011 Springer-Verlag. Fil:Perez-Etchegoyen, C.B. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Rodriguez, M.J. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Szczupak, L. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 2012 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03407594_v198_n3_p239_PerezEtchegoyen http://hdl.handle.net/20.500.12110/paper_03407594_v198_n3_p239_PerezEtchegoyen
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic Crawling
Excitability
Leech motoneuron
Motor control
Spike frequency adaptation
animal
article
cell membrane potential
leech
motoneuron
motor activity
physiology
synapse
synaptic transmission
Animals
Leeches
Membrane Potentials
Motor Activity
Motor Neurons
Synapses
Synaptic Transmission
spellingShingle Crawling
Excitability
Leech motoneuron
Motor control
Spike frequency adaptation
animal
article
cell membrane potential
leech
motoneuron
motor activity
physiology
synapse
synaptic transmission
Animals
Leeches
Membrane Potentials
Motor Activity
Motor Neurons
Synapses
Synaptic Transmission
Perez Etchegoyen, C. Bernardo
Rodríguez, Mariano Julián
Szczupak, Lidia
The activity of leech motoneurons during motor patterns is regulated by intrinsic properties and synaptic inputs
topic_facet Crawling
Excitability
Leech motoneuron
Motor control
Spike frequency adaptation
animal
article
cell membrane potential
leech
motoneuron
motor activity
physiology
synapse
synaptic transmission
Animals
Leeches
Membrane Potentials
Motor Activity
Motor Neurons
Synapses
Synaptic Transmission
description The activity of motoneurons during motor patterns depends on their intrinsic properties and on synaptic inputs. This study analyzed the properties of two leech motoneurons: the excitors of dorsal longitudinal muscles (DE-3) and of dorsal and ventral longitudinal muscles (MN-L) in basal conditions (normal and high Mg 2+ saline) and during crawling. The voltage-current relationships in DE-3 and MN-L were similar. The curves exhibited the largest slope around resting potential, showed marked inward and outward rectification, and were not affected by high Mg 2+. In response to 5-s pulses, DE-3 exhibited a fast initial adaptation, a slow recovery and a very slow late adaptation. High Mg 2+ abolished the initial high frequency. The frequency-voltage relationship for the rest of the response was highly similar in normal and in high Mg 2+ saline. MN-L exhibited a minor initial adaptation and then fired steadily. High Mg 2+ diminished the frequency-voltage relationship. During crawling DE-3 and MN-L fired in phase and their frequency-voltage curves overlapped with the lower end of the curves obtained in basal conditions. The results suggest that the activity of these motoneurons during crawling was regulated, to a large extent, by synaptic inputs. © 2011 Springer-Verlag.
author Perez Etchegoyen, C. Bernardo
Rodríguez, Mariano Julián
Szczupak, Lidia
author_facet Perez Etchegoyen, C. Bernardo
Rodríguez, Mariano Julián
Szczupak, Lidia
author_sort Perez Etchegoyen, C. Bernardo
title The activity of leech motoneurons during motor patterns is regulated by intrinsic properties and synaptic inputs
title_short The activity of leech motoneurons during motor patterns is regulated by intrinsic properties and synaptic inputs
title_full The activity of leech motoneurons during motor patterns is regulated by intrinsic properties and synaptic inputs
title_fullStr The activity of leech motoneurons during motor patterns is regulated by intrinsic properties and synaptic inputs
title_full_unstemmed The activity of leech motoneurons during motor patterns is regulated by intrinsic properties and synaptic inputs
title_sort activity of leech motoneurons during motor patterns is regulated by intrinsic properties and synaptic inputs
publishDate 2012
url https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03407594_v198_n3_p239_PerezEtchegoyen
http://hdl.handle.net/20.500.12110/paper_03407594_v198_n3_p239_PerezEtchegoyen
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