Differential channeling of sensory stimuli onto a motor neuron in the leech
We studied a specific sensory-motor pathway in the isolated leech ganglia. Pressure-sensitive mechanosensory neurons were stimulated with trains of action potentials at 5-20 Hz while recording the responses of the annulus erector motorneurons that control annuli erection. The response of the annulus...
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1999
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| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03407594_v184_n2_p233_Iscla http://hdl.handle.net/20.500.12110/paper_03407594_v184_n2_p233_Iscla |
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paper:paper_03407594_v184_n2_p233_Iscla2023-06-08T15:34:14Z Differential channeling of sensory stimuli onto a motor neuron in the leech Iscla, Irene Szczupak, Lidia Electric junction Leech Non-spiking interneuron Sensory integration Sensory-motor animal article calcium signaling cell membrane potential cytology electrophysiology electrostimulation excitatory postsynaptic potential ganglion in vitro study leech metabolism motoneuron nerve tract patch clamp physiology pressure sensory nerve cell stimulation Animals Calcium Signaling Electric Stimulation Electrophysiology Excitatory Postsynaptic Potentials Ganglia, Invertebrate Leeches Membrane Potentials Motor Neurons Neural Pathways Neurons, Afferent Patch-Clamp Techniques Physical Stimulation Pressure Animalia Hirudinida Invertebrata We studied a specific sensory-motor pathway in the isolated leech ganglia. Pressure-sensitive mechanosensory neurons were stimulated with trains of action potentials at 5-20 Hz while recording the responses of the annulus erector motorneurons that control annuli erection. The response of the annulus erector neurons was a succession of excitatory postsynaptic potentials followed by inhibitory postsynaptic potentials. The excitatory postsynaptic potentials had a brief time-course while the inhibitory postsynaptic potentials had a prolonged time-course that enabled their temporal summation. Thus, the net effect of pressure-sensitive neuron stimulation on the annulus erector neurons was inhibitory. Both phases of the response were mediated by chemical transmission; the excitatory postsynaptic potentials were transmitted via a monosynaptic pathway, and the inhibitory postsynaptic potentials via a polysynaptic one. The pattern of expression of this dual response depended on the field of innervation of the sensory neuron and it was under the influence of cell 151, a non-spiking interneuron, that could regulate the expression of the hyperpolarization. The interaction between pressure-sensitive neurons and annulus erector neuron reveals how sensory specificity, connectivity pattern and regulatory elements interplay in a specific sensory-motor network. Fil:Iscla, I. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Szczupak, L. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 1999 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03407594_v184_n2_p233_Iscla http://hdl.handle.net/20.500.12110/paper_03407594_v184_n2_p233_Iscla |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Electric junction Leech Non-spiking interneuron Sensory integration Sensory-motor animal article calcium signaling cell membrane potential cytology electrophysiology electrostimulation excitatory postsynaptic potential ganglion in vitro study leech metabolism motoneuron nerve tract patch clamp physiology pressure sensory nerve cell stimulation Animals Calcium Signaling Electric Stimulation Electrophysiology Excitatory Postsynaptic Potentials Ganglia, Invertebrate Leeches Membrane Potentials Motor Neurons Neural Pathways Neurons, Afferent Patch-Clamp Techniques Physical Stimulation Pressure Animalia Hirudinida Invertebrata |
| spellingShingle |
Electric junction Leech Non-spiking interneuron Sensory integration Sensory-motor animal article calcium signaling cell membrane potential cytology electrophysiology electrostimulation excitatory postsynaptic potential ganglion in vitro study leech metabolism motoneuron nerve tract patch clamp physiology pressure sensory nerve cell stimulation Animals Calcium Signaling Electric Stimulation Electrophysiology Excitatory Postsynaptic Potentials Ganglia, Invertebrate Leeches Membrane Potentials Motor Neurons Neural Pathways Neurons, Afferent Patch-Clamp Techniques Physical Stimulation Pressure Animalia Hirudinida Invertebrata Iscla, Irene Szczupak, Lidia Differential channeling of sensory stimuli onto a motor neuron in the leech |
| topic_facet |
Electric junction Leech Non-spiking interneuron Sensory integration Sensory-motor animal article calcium signaling cell membrane potential cytology electrophysiology electrostimulation excitatory postsynaptic potential ganglion in vitro study leech metabolism motoneuron nerve tract patch clamp physiology pressure sensory nerve cell stimulation Animals Calcium Signaling Electric Stimulation Electrophysiology Excitatory Postsynaptic Potentials Ganglia, Invertebrate Leeches Membrane Potentials Motor Neurons Neural Pathways Neurons, Afferent Patch-Clamp Techniques Physical Stimulation Pressure Animalia Hirudinida Invertebrata |
| description |
We studied a specific sensory-motor pathway in the isolated leech ganglia. Pressure-sensitive mechanosensory neurons were stimulated with trains of action potentials at 5-20 Hz while recording the responses of the annulus erector motorneurons that control annuli erection. The response of the annulus erector neurons was a succession of excitatory postsynaptic potentials followed by inhibitory postsynaptic potentials. The excitatory postsynaptic potentials had a brief time-course while the inhibitory postsynaptic potentials had a prolonged time-course that enabled their temporal summation. Thus, the net effect of pressure-sensitive neuron stimulation on the annulus erector neurons was inhibitory. Both phases of the response were mediated by chemical transmission; the excitatory postsynaptic potentials were transmitted via a monosynaptic pathway, and the inhibitory postsynaptic potentials via a polysynaptic one. The pattern of expression of this dual response depended on the field of innervation of the sensory neuron and it was under the influence of cell 151, a non-spiking interneuron, that could regulate the expression of the hyperpolarization. The interaction between pressure-sensitive neurons and annulus erector neuron reveals how sensory specificity, connectivity pattern and regulatory elements interplay in a specific sensory-motor network. |
| author |
Iscla, Irene Szczupak, Lidia |
| author_facet |
Iscla, Irene Szczupak, Lidia |
| author_sort |
Iscla, Irene |
| title |
Differential channeling of sensory stimuli onto a motor neuron in the leech |
| title_short |
Differential channeling of sensory stimuli onto a motor neuron in the leech |
| title_full |
Differential channeling of sensory stimuli onto a motor neuron in the leech |
| title_fullStr |
Differential channeling of sensory stimuli onto a motor neuron in the leech |
| title_full_unstemmed |
Differential channeling of sensory stimuli onto a motor neuron in the leech |
| title_sort |
differential channeling of sensory stimuli onto a motor neuron in the leech |
| publishDate |
1999 |
| url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03407594_v184_n2_p233_Iscla http://hdl.handle.net/20.500.12110/paper_03407594_v184_n2_p233_Iscla |
| work_keys_str_mv |
AT isclairene differentialchannelingofsensorystimuliontoamotorneuronintheleech AT szczupaklidia differentialchannelingofsensorystimuliontoamotorneuronintheleech |
| _version_ |
1768541612591284224 |