Synergistic antioxidant and antibacterial activity of rosemary plus butylated derivatives

Antioxidant and antibacterial activity of a methanol rosemary extract (RE) containing 30% carnosic acid (CA), 16% carnosol (COH) and 5% rosmarinic acid (RA) was studied in vitro alone and in combination with the antioxidant food additives butylated hydroxytoluene (BHT) and butylated hydroxyanisole (...

Descripción completa

Detalles Bibliográficos
Autores principales: Repetto, Maria Victoria, Vojnov, Adrian Alberto, Moreno de Colonna, Silvia
Publicado: 2009
Materias:
Antibacterial
Antioxidant
Carnosic acid
Polyphenols
Rosemary
Rosmarinic acid
Synergism
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03088146_v115_n2_p456_Romano
http://hdl.handle.net/20.500.12110/paper_03088146_v115_n2_p456_Romano
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
id paper:paper_03088146_v115_n2_p456_Romano
record_format dspace
spelling paper:paper_03088146_v115_n2_p456_Romano2023-06-08T15:31:40Z Synergistic antioxidant and antibacterial activity of rosemary plus butylated derivatives Repetto, Maria Victoria Vojnov, Adrian Alberto Moreno de Colonna, Silvia Antibacterial Antioxidant Carnosic acid Polyphenols Rosemary Rosmarinic acid Synergism Antioxidant and antibacterial activity of a methanol rosemary extract (RE) containing 30% carnosic acid (CA), 16% carnosol (COH) and 5% rosmarinic acid (RA) was studied in vitro alone and in combination with the antioxidant food additives butylated hydroxytoluene (BHT) and butylated hydroxyanisole (BHA). The antioxidant efficiency of the extract, CA, and RA, was determined by a kinetic analysis of the 2,2-diphenyl-2-picrylhydrazyl hydrate radical (DPPH·) scavenging activity. RE showed two different rate slopes in the reduction of DPPH· vs. time curve, which correlated with the distinct behaviours of RA and CA; pure RA reached the plateau more rapidly than CA. A synergistic antioxidant effect between RE and BHT was demonstrated by isobolographic analysis and a synergistic interaction of RE with BHA to inhibit Escherichia coli and Staphylococcus aureus growth was observed. Therefore, rosemary not only enhances the antioxidant efficiency of BHA and BHT, but also the antibacterial effect of BHA; allowing a decrease from 4.4 to17 folds in the amounts of the synthetic compounds used. © 2008 Elsevier Ltd. All rights reserved. Fil:Repetto, V. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Vojnov, A.A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Moreno, S. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 2009 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03088146_v115_n2_p456_Romano http://hdl.handle.net/20.500.12110/paper_03088146_v115_n2_p456_Romano
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic Antibacterial
Antioxidant
Carnosic acid
Polyphenols
Rosemary
Rosmarinic acid
Synergism
spellingShingle Antibacterial
Antioxidant
Carnosic acid
Polyphenols
Rosemary
Rosmarinic acid
Synergism
Repetto, Maria Victoria
Vojnov, Adrian Alberto
Moreno de Colonna, Silvia
Synergistic antioxidant and antibacterial activity of rosemary plus butylated derivatives
topic_facet Antibacterial
Antioxidant
Carnosic acid
Polyphenols
Rosemary
Rosmarinic acid
Synergism
description Antioxidant and antibacterial activity of a methanol rosemary extract (RE) containing 30% carnosic acid (CA), 16% carnosol (COH) and 5% rosmarinic acid (RA) was studied in vitro alone and in combination with the antioxidant food additives butylated hydroxytoluene (BHT) and butylated hydroxyanisole (BHA). The antioxidant efficiency of the extract, CA, and RA, was determined by a kinetic analysis of the 2,2-diphenyl-2-picrylhydrazyl hydrate radical (DPPH·) scavenging activity. RE showed two different rate slopes in the reduction of DPPH· vs. time curve, which correlated with the distinct behaviours of RA and CA; pure RA reached the plateau more rapidly than CA. A synergistic antioxidant effect between RE and BHT was demonstrated by isobolographic analysis and a synergistic interaction of RE with BHA to inhibit Escherichia coli and Staphylococcus aureus growth was observed. Therefore, rosemary not only enhances the antioxidant efficiency of BHA and BHT, but also the antibacterial effect of BHA; allowing a decrease from 4.4 to17 folds in the amounts of the synthetic compounds used. © 2008 Elsevier Ltd. All rights reserved.
author Repetto, Maria Victoria
Vojnov, Adrian Alberto
Moreno de Colonna, Silvia
author_facet Repetto, Maria Victoria
Vojnov, Adrian Alberto
Moreno de Colonna, Silvia
author_sort Repetto, Maria Victoria
title Synergistic antioxidant and antibacterial activity of rosemary plus butylated derivatives
title_short Synergistic antioxidant and antibacterial activity of rosemary plus butylated derivatives
title_full Synergistic antioxidant and antibacterial activity of rosemary plus butylated derivatives
title_fullStr Synergistic antioxidant and antibacterial activity of rosemary plus butylated derivatives
title_full_unstemmed Synergistic antioxidant and antibacterial activity of rosemary plus butylated derivatives
title_sort synergistic antioxidant and antibacterial activity of rosemary plus butylated derivatives
publishDate 2009
url https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03088146_v115_n2_p456_Romano
http://hdl.handle.net/20.500.12110/paper_03088146_v115_n2_p456_Romano
work_keys_str_mv AT repettomariavictoria synergisticantioxidantandantibacterialactivityofrosemaryplusbutylatedderivatives
AT vojnovadrianalberto synergisticantioxidantandantibacterialactivityofrosemaryplusbutylatedderivatives
AT morenodecolonnasilvia synergisticantioxidantandantibacterialactivityofrosemaryplusbutylatedderivatives
_version_ 1768544132182048768

Ejemplares similares