Mouse mammary carcinoma δ-aminolevulinate dehydratase
1. 1. Aminolevulinate dehydratase (ALA-D) was studied in crude extract from mouse mammary carcinoma, normal mouse liver and tumour bearing mouse liver. 2. 2. A Michaelis-Menten behaviour and Km values between 0.24 and 0.31 mM were obtained for the enzyme in either source. 3. 3. In all three tissues...
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1990
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Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03050491_v96_n4_p729_Navone http://hdl.handle.net/20.500.12110/paper_03050491_v96_n4_p729_Navone |
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paper:paper_03050491_v96_n4_p729_Navone2023-06-08T15:30:25Z Mouse mammary carcinoma δ-aminolevulinate dehydratase Batlle, Alcira María del Carmen liver enzyme porphobilinogen synthase animal cell article breast cancer enzyme kinetics mouse nonhuman priority journal Animal Enzyme Stability Heat Hydrogen-Ion Concentration Kinetics Liver Male Mammary Neoplasms, Experimental Mice Mice, Inbred BALB C Porphobilinogen Porphobilinogen Synthase Support, Non-U.S. Gov't Animalia 1. 1. Aminolevulinate dehydratase (ALA-D) was studied in crude extract from mouse mammary carcinoma, normal mouse liver and tumour bearing mouse liver. 2. 2. A Michaelis-Menten behaviour and Km values between 0.24 and 0.31 mM were obtained for the enzyme in either source. 3. 3. In all three tissues there was a linear relationship between porphobilinogen formation and incubation time, up to 120 min, ALA-D was thermostable and optimum pH was at 6.8. 4. 4. There seems to be no structural alterations in tumoural ALA-D as compared with the enzyme from liver of both normal and tumour bearing mice. © 1990. Fil:Batlle, A.M.D.C. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 1990 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03050491_v96_n4_p729_Navone http://hdl.handle.net/20.500.12110/paper_03050491_v96_n4_p729_Navone |
institution |
Universidad de Buenos Aires |
institution_str |
I-28 |
repository_str |
R-134 |
collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
topic |
liver enzyme porphobilinogen synthase animal cell article breast cancer enzyme kinetics mouse nonhuman priority journal Animal Enzyme Stability Heat Hydrogen-Ion Concentration Kinetics Liver Male Mammary Neoplasms, Experimental Mice Mice, Inbred BALB C Porphobilinogen Porphobilinogen Synthase Support, Non-U.S. Gov't Animalia |
spellingShingle |
liver enzyme porphobilinogen synthase animal cell article breast cancer enzyme kinetics mouse nonhuman priority journal Animal Enzyme Stability Heat Hydrogen-Ion Concentration Kinetics Liver Male Mammary Neoplasms, Experimental Mice Mice, Inbred BALB C Porphobilinogen Porphobilinogen Synthase Support, Non-U.S. Gov't Animalia Batlle, Alcira María del Carmen Mouse mammary carcinoma δ-aminolevulinate dehydratase |
topic_facet |
liver enzyme porphobilinogen synthase animal cell article breast cancer enzyme kinetics mouse nonhuman priority journal Animal Enzyme Stability Heat Hydrogen-Ion Concentration Kinetics Liver Male Mammary Neoplasms, Experimental Mice Mice, Inbred BALB C Porphobilinogen Porphobilinogen Synthase Support, Non-U.S. Gov't Animalia |
description |
1. 1. Aminolevulinate dehydratase (ALA-D) was studied in crude extract from mouse mammary carcinoma, normal mouse liver and tumour bearing mouse liver. 2. 2. A Michaelis-Menten behaviour and Km values between 0.24 and 0.31 mM were obtained for the enzyme in either source. 3. 3. In all three tissues there was a linear relationship between porphobilinogen formation and incubation time, up to 120 min, ALA-D was thermostable and optimum pH was at 6.8. 4. 4. There seems to be no structural alterations in tumoural ALA-D as compared with the enzyme from liver of both normal and tumour bearing mice. © 1990. |
author |
Batlle, Alcira María del Carmen |
author_facet |
Batlle, Alcira María del Carmen |
author_sort |
Batlle, Alcira María del Carmen |
title |
Mouse mammary carcinoma δ-aminolevulinate dehydratase |
title_short |
Mouse mammary carcinoma δ-aminolevulinate dehydratase |
title_full |
Mouse mammary carcinoma δ-aminolevulinate dehydratase |
title_fullStr |
Mouse mammary carcinoma δ-aminolevulinate dehydratase |
title_full_unstemmed |
Mouse mammary carcinoma δ-aminolevulinate dehydratase |
title_sort |
mouse mammary carcinoma δ-aminolevulinate dehydratase |
publishDate |
1990 |
url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03050491_v96_n4_p729_Navone http://hdl.handle.net/20.500.12110/paper_03050491_v96_n4_p729_Navone |
work_keys_str_mv |
AT batllealciramariadelcarmen mousemammarycarcinomadaminolevulinatedehydratase |
_version_ |
1768542596999675904 |