A mouse attenuated mutant of Junin virus with an altered envelope glycoprotein

The XJCl3 strain of Junin virus (JV) and the mouse-attenuated mutant Cl67 showed different GP 38 peptide mapping after limited proteolysis with ficin and papain; viral infectivity of both viruses also exhibited a different susceptibility to protease treatment. A correlation between envelope glycopro...

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Autores principales:	Scolaro, Luis Alberto, Mersich, Susana E., Damonte, Elsa Beatriz
Publicado:	1990
Materias:	virus envelope protein virus glycoprotein article junin virus nonhuman virus attenuation Animal Arenaviridae Arenaviruses, New World Electrophoresis, Polyacrylamide Gel Glycoproteins Mice Mutation Peptide Mapping Support, Non-U.S. Gov't Viral Envelope Proteins Virus Replication Junin virus
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03048608_v111_n3-4_p257_Scolaro http://hdl.handle.net/20.500.12110/paper_03048608_v111_n3-4_p257_Scolaro
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	paper:paper_03048608_v111_n3-4_p257_Scolaro
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spelling	paper:paper_03048608_v111_n3-4_p257_Scolaro2023-06-08T15:30:01Z A mouse attenuated mutant of Junin virus with an altered envelope glycoprotein Scolaro, Luis Alberto Mersich, Susana E. Damonte, Elsa Beatriz virus envelope protein virus glycoprotein article junin virus nonhuman virus attenuation Animal Arenaviridae Arenaviruses, New World Electrophoresis, Polyacrylamide Gel Glycoproteins Mice Mutation Peptide Mapping Support, Non-U.S. Gov't Viral Envelope Proteins Virus Replication Junin virus The XJCl3 strain of Junin virus (JV) and the mouse-attenuated mutant Cl67 showed different GP 38 peptide mapping after limited proteolysis with ficin and papain; viral infectivity of both viruses also exhibited a different susceptibility to protease treatment. A correlation between envelope glycoprotein alteration and JV virulence in neonatal mice is proposed. © 1990 Springer-Verlag. Fil:Scolaro, L.A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Mersich, S.E. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Damonte, E.B. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 1990 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03048608_v111_n3-4_p257_Scolaro http://hdl.handle.net/20.500.12110/paper_03048608_v111_n3-4_p257_Scolaro
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	virus envelope protein virus glycoprotein article junin virus nonhuman virus attenuation Animal Arenaviridae Arenaviruses, New World Electrophoresis, Polyacrylamide Gel Glycoproteins Mice Mutation Peptide Mapping Support, Non-U.S. Gov't Viral Envelope Proteins Virus Replication Junin virus
spellingShingle	virus envelope protein virus glycoprotein article junin virus nonhuman virus attenuation Animal Arenaviridae Arenaviruses, New World Electrophoresis, Polyacrylamide Gel Glycoproteins Mice Mutation Peptide Mapping Support, Non-U.S. Gov't Viral Envelope Proteins Virus Replication Junin virus Scolaro, Luis Alberto Mersich, Susana E. Damonte, Elsa Beatriz A mouse attenuated mutant of Junin virus with an altered envelope glycoprotein
topic_facet	virus envelope protein virus glycoprotein article junin virus nonhuman virus attenuation Animal Arenaviridae Arenaviruses, New World Electrophoresis, Polyacrylamide Gel Glycoproteins Mice Mutation Peptide Mapping Support, Non-U.S. Gov't Viral Envelope Proteins Virus Replication Junin virus
description	The XJCl3 strain of Junin virus (JV) and the mouse-attenuated mutant Cl67 showed different GP 38 peptide mapping after limited proteolysis with ficin and papain; viral infectivity of both viruses also exhibited a different susceptibility to protease treatment. A correlation between envelope glycoprotein alteration and JV virulence in neonatal mice is proposed. © 1990 Springer-Verlag.
author	Scolaro, Luis Alberto Mersich, Susana E. Damonte, Elsa Beatriz
author_facet	Scolaro, Luis Alberto Mersich, Susana E. Damonte, Elsa Beatriz
author_sort	Scolaro, Luis Alberto
title	A mouse attenuated mutant of Junin virus with an altered envelope glycoprotein
title_short	A mouse attenuated mutant of Junin virus with an altered envelope glycoprotein
title_full	A mouse attenuated mutant of Junin virus with an altered envelope glycoprotein
title_fullStr	A mouse attenuated mutant of Junin virus with an altered envelope glycoprotein
title_full_unstemmed	A mouse attenuated mutant of Junin virus with an altered envelope glycoprotein
title_sort	mouse attenuated mutant of junin virus with an altered envelope glycoprotein
publishDate	1990
url	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03048608_v111_n3-4_p257_Scolaro http://hdl.handle.net/20.500.12110/paper_03048608_v111_n3-4_p257_Scolaro
work_keys_str_mv	AT scolaroluisalberto amouseattenuatedmutantofjuninviruswithanalteredenvelopeglycoprotein AT mersichsusanae amouseattenuatedmutantofjuninviruswithanalteredenvelopeglycoprotein AT damonteelsabeatriz amouseattenuatedmutantofjuninviruswithanalteredenvelopeglycoprotein AT scolaroluisalberto mouseattenuatedmutantofjuninviruswithanalteredenvelopeglycoprotein AT mersichsusanae mouseattenuatedmutantofjuninviruswithanalteredenvelopeglycoprotein AT damonteelsabeatriz mouseattenuatedmutantofjuninviruswithanalteredenvelopeglycoprotein
_version_	1768541845280784384

A mouse attenuated mutant of Junin virus with an altered envelope glycoprotein

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