DNA topoisomerase I from Leydig cells is modulated by luteinizing hormone and cyclic adenosine monophosphate

The action of luteinizing hormone on topoisomerase I activity from rat Leydig cells was studied. Stimulation of the enzyme was observed after long-term (24 and 48 h) gonadotrophin treatment in in vivo experiments. No change could be detected for shorter times than 12 h using two different experiment...

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Detalles Bibliográficos
Publicado: 1987
Materias:
DNA topoisomerase I
Leydig cell
Nuclear effect
Peptide hormone
cyclic amp
dna
dna topoisomerase
luteinizing hormone
peptide
animal cell
leydig cell
male genital system
nonhuman
nucleus
priority journal
rat
Animals
Carrier Proteins
Cyclic AMP
DNA Topoisomerases, Type I
Gonadotropins
Intracellular Signaling Peptides and Proteins
Leydig Cells
Luteinizing Hormone
Male
Rats
Rats, Inbred Strains
Testosterone
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03037207_v53_n3_p221_Crespi
http://hdl.handle.net/20.500.12110/paper_03037207_v53_n3_p221_Crespi
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
id paper:paper_03037207_v53_n3_p221_Crespi
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spelling paper:paper_03037207_v53_n3_p221_Crespi2023-06-08T15:29:14Z DNA topoisomerase I from Leydig cells is modulated by luteinizing hormone and cyclic adenosine monophosphate DNA topoisomerase I Leydig cell Nuclear effect Peptide hormone cyclic amp dna dna topoisomerase luteinizing hormone peptide animal cell leydig cell male genital system nonhuman nucleus priority journal rat Animals Carrier Proteins Cyclic AMP DNA Topoisomerases, Type I Gonadotropins Intracellular Signaling Peptides and Proteins Leydig Cells Luteinizing Hormone Male Rats Rats, Inbred Strains Testosterone The action of luteinizing hormone on topoisomerase I activity from rat Leydig cells was studied. Stimulation of the enzyme was observed after long-term (24 and 48 h) gonadotrophin treatment in in vivo experiments. No change could be detected for shorter times than 12 h using two different experimental approaches. Topoisomerase I was stimulated by cAMP in a whole cell extract in a phosphorylation-dependent manner. These results suggest that topoisomerase I could be a target for nuclear events induced by peptide hormone action. © 1987. 1987 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03037207_v53_n3_p221_Crespi http://hdl.handle.net/20.500.12110/paper_03037207_v53_n3_p221_Crespi
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic DNA topoisomerase I
Leydig cell
Nuclear effect
Peptide hormone
cyclic amp
dna
dna topoisomerase
luteinizing hormone
peptide
animal cell
leydig cell
male genital system
nonhuman
nucleus
priority journal
rat
Animals
Carrier Proteins
Cyclic AMP
DNA Topoisomerases, Type I
Gonadotropins
Intracellular Signaling Peptides and Proteins
Leydig Cells
Luteinizing Hormone
Male
Rats
Rats, Inbred Strains
Testosterone
spellingShingle DNA topoisomerase I
Leydig cell
Nuclear effect
Peptide hormone
cyclic amp
dna
dna topoisomerase
luteinizing hormone
peptide
animal cell
leydig cell
male genital system
nonhuman
nucleus
priority journal
rat
Animals
Carrier Proteins
Cyclic AMP
DNA Topoisomerases, Type I
Gonadotropins
Intracellular Signaling Peptides and Proteins
Leydig Cells
Luteinizing Hormone
Male
Rats
Rats, Inbred Strains
Testosterone
DNA topoisomerase I from Leydig cells is modulated by luteinizing hormone and cyclic adenosine monophosphate
topic_facet DNA topoisomerase I
Leydig cell
Nuclear effect
Peptide hormone
cyclic amp
dna
dna topoisomerase
luteinizing hormone
peptide
animal cell
leydig cell
male genital system
nonhuman
nucleus
priority journal
rat
Animals
Carrier Proteins
Cyclic AMP
DNA Topoisomerases, Type I
Gonadotropins
Intracellular Signaling Peptides and Proteins
Leydig Cells
Luteinizing Hormone
Male
Rats
Rats, Inbred Strains
Testosterone
description The action of luteinizing hormone on topoisomerase I activity from rat Leydig cells was studied. Stimulation of the enzyme was observed after long-term (24 and 48 h) gonadotrophin treatment in in vivo experiments. No change could be detected for shorter times than 12 h using two different experimental approaches. Topoisomerase I was stimulated by cAMP in a whole cell extract in a phosphorylation-dependent manner. These results suggest that topoisomerase I could be a target for nuclear events induced by peptide hormone action. © 1987.
title DNA topoisomerase I from Leydig cells is modulated by luteinizing hormone and cyclic adenosine monophosphate
title_short DNA topoisomerase I from Leydig cells is modulated by luteinizing hormone and cyclic adenosine monophosphate
title_full DNA topoisomerase I from Leydig cells is modulated by luteinizing hormone and cyclic adenosine monophosphate
title_fullStr DNA topoisomerase I from Leydig cells is modulated by luteinizing hormone and cyclic adenosine monophosphate
title_full_unstemmed DNA topoisomerase I from Leydig cells is modulated by luteinizing hormone and cyclic adenosine monophosphate
title_sort dna topoisomerase i from leydig cells is modulated by luteinizing hormone and cyclic adenosine monophosphate
publishDate 1987
url https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03037207_v53_n3_p221_Crespi
http://hdl.handle.net/20.500.12110/paper_03037207_v53_n3_p221_Crespi
_version_ 1768542691924115456

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