Water balance effects of systemic and intracerebroventricular administration of angiotensin II in the toad Bufo arenarum
1. 1. Systemic administration of angiotensin II (10 μg/kg) to fully hydrated toads decreased urine production but did not affect natripheric or hydrosmotic water fluxes across the skin. 2. 2. The antidiuretic response was not modified by the simultaneous α-adrenergic blocking with tolazoline (5 mg/k...
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1989
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| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03009629_v93_n3_p505_Reboreda http://hdl.handle.net/20.500.12110/paper_03009629_v93_n3_p505_Reboreda |
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paper:paper_03009629_v93_n3_p505_Reboreda |
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paper:paper_03009629_v93_n3_p505_Reboreda2023-06-08T15:27:46Z Water balance effects of systemic and intracerebroventricular administration of angiotensin II in the toad Bufo arenarum angiotensin saralasin tolazoline animal experiment controlled study fluid balance intracerebroventricular drug administration intralymphatic drug administration male nonhuman osmoregulation toad uropoiesis 1. 1. Systemic administration of angiotensin II (10 μg/kg) to fully hydrated toads decreased urine production but did not affect natripheric or hydrosmotic water fluxes across the skin. 2. 2. The antidiuretic response was not modified by the simultaneous α-adrenergic blocking with tolazoline (5 mg/kg). 3. 3. In a similar way, single intracerebroventricular injections of 1 μl 10-4M angiotensin II, decreased urine production but did not affect water uptake. 4. 4. Finally, systemic injections of the angiotensin blocker salarasin (100 μg/kg) did not affect the cutaneous hydrosmotic response of dehydrated toads. 5. 5. We conclude that angiotensin II has no effects on water uptake in this species. The antidiuretic response to angiotensin II, and the involvement of adrenergic mechanisms are discussed. © 1989. 1989 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03009629_v93_n3_p505_Reboreda http://hdl.handle.net/20.500.12110/paper_03009629_v93_n3_p505_Reboreda |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
angiotensin saralasin tolazoline animal experiment controlled study fluid balance intracerebroventricular drug administration intralymphatic drug administration male nonhuman osmoregulation toad uropoiesis |
| spellingShingle |
angiotensin saralasin tolazoline animal experiment controlled study fluid balance intracerebroventricular drug administration intralymphatic drug administration male nonhuman osmoregulation toad uropoiesis Water balance effects of systemic and intracerebroventricular administration of angiotensin II in the toad Bufo arenarum |
| topic_facet |
angiotensin saralasin tolazoline animal experiment controlled study fluid balance intracerebroventricular drug administration intralymphatic drug administration male nonhuman osmoregulation toad uropoiesis |
| description |
1. 1. Systemic administration of angiotensin II (10 μg/kg) to fully hydrated toads decreased urine production but did not affect natripheric or hydrosmotic water fluxes across the skin. 2. 2. The antidiuretic response was not modified by the simultaneous α-adrenergic blocking with tolazoline (5 mg/kg). 3. 3. In a similar way, single intracerebroventricular injections of 1 μl 10-4M angiotensin II, decreased urine production but did not affect water uptake. 4. 4. Finally, systemic injections of the angiotensin blocker salarasin (100 μg/kg) did not affect the cutaneous hydrosmotic response of dehydrated toads. 5. 5. We conclude that angiotensin II has no effects on water uptake in this species. The antidiuretic response to angiotensin II, and the involvement of adrenergic mechanisms are discussed. © 1989. |
| title |
Water balance effects of systemic and intracerebroventricular administration of angiotensin II in the toad Bufo arenarum |
| title_short |
Water balance effects of systemic and intracerebroventricular administration of angiotensin II in the toad Bufo arenarum |
| title_full |
Water balance effects of systemic and intracerebroventricular administration of angiotensin II in the toad Bufo arenarum |
| title_fullStr |
Water balance effects of systemic and intracerebroventricular administration of angiotensin II in the toad Bufo arenarum |
| title_full_unstemmed |
Water balance effects of systemic and intracerebroventricular administration of angiotensin II in the toad Bufo arenarum |
| title_sort |
water balance effects of systemic and intracerebroventricular administration of angiotensin ii in the toad bufo arenarum |
| publishDate |
1989 |
| url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03009629_v93_n3_p505_Reboreda http://hdl.handle.net/20.500.12110/paper_03009629_v93_n3_p505_Reboreda |
| _version_ |
1768545418164043776 |