Lipid-bound sugars in malignant human breast tumors - Partial characterization of mannosyl and glucosyl transferase activities
Microsomal preparations from malignant human breast tumors catalyzed the transfer of mannose and glucose from GDP-[14C]-Man and UDP-[14C]-Glc into lipid-linked sugars and glycoprotein-like substances. As judged by several criteria the obtained lipid-linked monosaccharides behaved as dolichyl phospha...
Guardado en:
| Publicado: |
1983
|
|---|---|
| Materias: | |
| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03008177_v56_n1_p55_SantaCruza http://hdl.handle.net/20.500.12110/paper_03008177_v56_n1_p55_SantaCruza |
| Aporte de: |
| id |
paper:paper_03008177_v56_n1_p55_SantaCruza |
|---|---|
| record_format |
dspace |
| spelling |
paper:paper_03008177_v56_n1_p55_SantaCruza2023-06-08T15:27:30Z Lipid-bound sugars in malignant human breast tumors - Partial characterization of mannosyl and glucosyl transferase activities carbon diagnostic agent glucosyltransferase glycoprotein glycosyltransferase guanosine diphosphate mannose isoprenoid phosphate sugar mannosyltransferase nucleoside diphosphate sugar uridine diphosphate glucose uridine diphosphate sugar article biosynthesis breast tumor enzymology female human kinetics metabolism microsome Breast Neoplasms Carbon Radioisotopes Female Glucosyltransferases Glycoproteins Guanosine Diphosphate Mannose Hexosyltransferases Human Kinetics Mannosyltransferases Microsomes Nucleoside Diphosphate Sugars Polyisoprenyl Phosphate Oligosaccharides Support, Non-U.S. Gov't Uridine Diphosphate Glucose Uridine Diphosphate Sugars Microsomal preparations from malignant human breast tumors catalyzed the transfer of mannose and glucose from GDP-[14C]-Man and UDP-[14C]-Glc into lipid-linked sugars and glycoprotein-like substances. As judged by several criteria the obtained lipid-linked monosaccharides behaved as dolichyl phosphate mannose and dolichyl phosphate glucose whereas lipid-linked oligosaccharides behaved as polyprenyl diphosphate derivatives. The optimum conditions for mannosyl and glucosyl - transfer reactions and the effect of dolichyl phosphate, detergent and EDTA on incubation mixture were described. © 1983 Martinus Nijhoff Publishers. 1983 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03008177_v56_n1_p55_SantaCruza http://hdl.handle.net/20.500.12110/paper_03008177_v56_n1_p55_SantaCruza |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
carbon diagnostic agent glucosyltransferase glycoprotein glycosyltransferase guanosine diphosphate mannose isoprenoid phosphate sugar mannosyltransferase nucleoside diphosphate sugar uridine diphosphate glucose uridine diphosphate sugar article biosynthesis breast tumor enzymology female human kinetics metabolism microsome Breast Neoplasms Carbon Radioisotopes Female Glucosyltransferases Glycoproteins Guanosine Diphosphate Mannose Hexosyltransferases Human Kinetics Mannosyltransferases Microsomes Nucleoside Diphosphate Sugars Polyisoprenyl Phosphate Oligosaccharides Support, Non-U.S. Gov't Uridine Diphosphate Glucose Uridine Diphosphate Sugars |
| spellingShingle |
carbon diagnostic agent glucosyltransferase glycoprotein glycosyltransferase guanosine diphosphate mannose isoprenoid phosphate sugar mannosyltransferase nucleoside diphosphate sugar uridine diphosphate glucose uridine diphosphate sugar article biosynthesis breast tumor enzymology female human kinetics metabolism microsome Breast Neoplasms Carbon Radioisotopes Female Glucosyltransferases Glycoproteins Guanosine Diphosphate Mannose Hexosyltransferases Human Kinetics Mannosyltransferases Microsomes Nucleoside Diphosphate Sugars Polyisoprenyl Phosphate Oligosaccharides Support, Non-U.S. Gov't Uridine Diphosphate Glucose Uridine Diphosphate Sugars Lipid-bound sugars in malignant human breast tumors - Partial characterization of mannosyl and glucosyl transferase activities |
| topic_facet |
carbon diagnostic agent glucosyltransferase glycoprotein glycosyltransferase guanosine diphosphate mannose isoprenoid phosphate sugar mannosyltransferase nucleoside diphosphate sugar uridine diphosphate glucose uridine diphosphate sugar article biosynthesis breast tumor enzymology female human kinetics metabolism microsome Breast Neoplasms Carbon Radioisotopes Female Glucosyltransferases Glycoproteins Guanosine Diphosphate Mannose Hexosyltransferases Human Kinetics Mannosyltransferases Microsomes Nucleoside Diphosphate Sugars Polyisoprenyl Phosphate Oligosaccharides Support, Non-U.S. Gov't Uridine Diphosphate Glucose Uridine Diphosphate Sugars |
| description |
Microsomal preparations from malignant human breast tumors catalyzed the transfer of mannose and glucose from GDP-[14C]-Man and UDP-[14C]-Glc into lipid-linked sugars and glycoprotein-like substances. As judged by several criteria the obtained lipid-linked monosaccharides behaved as dolichyl phosphate mannose and dolichyl phosphate glucose whereas lipid-linked oligosaccharides behaved as polyprenyl diphosphate derivatives. The optimum conditions for mannosyl and glucosyl - transfer reactions and the effect of dolichyl phosphate, detergent and EDTA on incubation mixture were described. © 1983 Martinus Nijhoff Publishers. |
| title |
Lipid-bound sugars in malignant human breast tumors - Partial characterization of mannosyl and glucosyl transferase activities |
| title_short |
Lipid-bound sugars in malignant human breast tumors - Partial characterization of mannosyl and glucosyl transferase activities |
| title_full |
Lipid-bound sugars in malignant human breast tumors - Partial characterization of mannosyl and glucosyl transferase activities |
| title_fullStr |
Lipid-bound sugars in malignant human breast tumors - Partial characterization of mannosyl and glucosyl transferase activities |
| title_full_unstemmed |
Lipid-bound sugars in malignant human breast tumors - Partial characterization of mannosyl and glucosyl transferase activities |
| title_sort |
lipid-bound sugars in malignant human breast tumors - partial characterization of mannosyl and glucosyl transferase activities |
| publishDate |
1983 |
| url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03008177_v56_n1_p55_SantaCruza http://hdl.handle.net/20.500.12110/paper_03008177_v56_n1_p55_SantaCruza |
| _version_ |
1768542644898627584 |