Toxicity of hexachlorobenzene and its transference from microalgae (Chlorella kessleri) to crabs (Chasmagnathus granulatus)

The aim of this work was to study the transference of hexachlorobenzene from a green alga (Chlorella kessleri) to an estuary crab (Chasmagnathus granulatus), and to analyze the toxic effects that the xenobiotic has on the latter. The effect of hexachlorobenzene uptake was evaluated measuring oxidati...

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Autores principales:	Chaufan, Rosa Gabriela, Juárez, Angela Beatriz, Ithuralde, Raul Esteban, Sabatini, Sebastián Eduardo, Genovese, Griselda, Kesten, Eva Marta, Ríos de Molina, María del Carmen
Publicado:	2006
Materias:	Chasmagnathus granulatus Chlorella kessleri Hexachlorobenzene Oxidative stress Uroporphyrinogen decarboxylase glutathione hexachlorobenzene lipid malonaldehyde superoxide dismutase uroporphyrinogen decarboxylase animal cell animal experiment animal tissue antioxidant activity article bioaccumulation chasmagnathus granulatus controlled study crab down regulation enzyme activity epithelium estuary evaluation green alga hepatopancreas histology lipid peroxidation liver injury male measurement morphometrics nonhuman oxidative stress pancreas injury priority journal sea pollution toxicology transference Animals Antioxidants Brachyura Chlorella Epithelium Food Chain Glutathione Hepatopancreas Lipid Peroxidation Malondialdehyde Superoxide Dismutase Tissue Distribution Xenobiotics algae Chasmagnathus granulata Chlorophyta Decapoda (Crustacea) Parachlorella kessleri
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0300483X_v227_n3_p262_Chaufan http://hdl.handle.net/20.500.12110/paper_0300483X_v227_n3_p262_Chaufan
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	paper:paper_0300483X_v227_n3_p262_Chaufan
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spelling	paper:paper_0300483X_v227_n3_p262_Chaufan2023-06-08T15:27:17Z Toxicity of hexachlorobenzene and its transference from microalgae (Chlorella kessleri) to crabs (Chasmagnathus granulatus) Chaufan, Rosa Gabriela Juárez, Angela Beatriz Ithuralde, Raul Esteban Sabatini, Sebastián Eduardo Genovese, Griselda Kesten, Eva Marta Ríos de Molina, María del Carmen Chasmagnathus granulatus Chlorella kessleri Hexachlorobenzene Oxidative stress Uroporphyrinogen decarboxylase glutathione hexachlorobenzene lipid malonaldehyde superoxide dismutase uroporphyrinogen decarboxylase animal cell animal experiment animal tissue antioxidant activity article bioaccumulation chasmagnathus granulatus Chlorella kessleri controlled study crab down regulation enzyme activity epithelium estuary evaluation green alga hepatopancreas histology lipid peroxidation liver injury male measurement morphometrics nonhuman oxidative stress pancreas injury priority journal sea pollution toxicology transference Animals Antioxidants Brachyura Chlorella Epithelium Food Chain Glutathione Hepatopancreas Hexachlorobenzene Lipid Peroxidation Malondialdehyde Superoxide Dismutase Tissue Distribution Xenobiotics algae Chasmagnathus granulata Chlorophyta Decapoda (Crustacea) Parachlorella kessleri The aim of this work was to study the transference of hexachlorobenzene from a green alga (Chlorella kessleri) to an estuary crab (Chasmagnathus granulatus), and to analyze the toxic effects that the xenobiotic has on the latter. The effect of hexachlorobenzene uptake was evaluated measuring oxidative stress, Uroporphyrinogen decarboxylase activity and morphometric parameter alteration, and also performing a histological analysis of crab hepatopancreas. Results demonstrated that hexachlorobenzene enters the alga, is accumulated in it, and then transferred into the crab, causing a decrease in Uroporphyrinogen decarboxylase activity in both organisms. The high malondialdehyde levels detected in crab hepatopancreas after the toxic treatment suggested the existence of hexachlorobenzene-induced lipid peroxidation. Antioxidant defenses such as superoxide dismutase activity and reduced glutathione content fell below normal values on the fourth week of treatment. At the same time, the hepatosomatic index, used as a morphometric parameter, reduced 20% with respect to the control. The histological analysis revealed epithelium disorganization in hepatopancreas tubules, confirming the existence of structural damage caused by hexachlorobenzene. © 2006 Elsevier Ireland Ltd. All rights reserved. Fil:Chaufan, G. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Juárez, A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Ithuralde, E. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Sabatini, S.E. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Genovese, G. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Kesten, E. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Ríos de Molina, M.d.C. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 2006 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0300483X_v227_n3_p262_Chaufan http://hdl.handle.net/20.500.12110/paper_0300483X_v227_n3_p262_Chaufan
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	Chasmagnathus granulatus Chlorella kessleri Hexachlorobenzene Oxidative stress Uroporphyrinogen decarboxylase glutathione hexachlorobenzene lipid malonaldehyde superoxide dismutase uroporphyrinogen decarboxylase animal cell animal experiment animal tissue antioxidant activity article bioaccumulation chasmagnathus granulatus Chlorella kessleri controlled study crab down regulation enzyme activity epithelium estuary evaluation green alga hepatopancreas histology lipid peroxidation liver injury male measurement morphometrics nonhuman oxidative stress pancreas injury priority journal sea pollution toxicology transference Animals Antioxidants Brachyura Chlorella Epithelium Food Chain Glutathione Hepatopancreas Hexachlorobenzene Lipid Peroxidation Malondialdehyde Superoxide Dismutase Tissue Distribution Xenobiotics algae Chasmagnathus granulata Chlorophyta Decapoda (Crustacea) Parachlorella kessleri
spellingShingle	Chasmagnathus granulatus Chlorella kessleri Hexachlorobenzene Oxidative stress Uroporphyrinogen decarboxylase glutathione hexachlorobenzene lipid malonaldehyde superoxide dismutase uroporphyrinogen decarboxylase animal cell animal experiment animal tissue antioxidant activity article bioaccumulation chasmagnathus granulatus Chlorella kessleri controlled study crab down regulation enzyme activity epithelium estuary evaluation green alga hepatopancreas histology lipid peroxidation liver injury male measurement morphometrics nonhuman oxidative stress pancreas injury priority journal sea pollution toxicology transference Animals Antioxidants Brachyura Chlorella Epithelium Food Chain Glutathione Hepatopancreas Hexachlorobenzene Lipid Peroxidation Malondialdehyde Superoxide Dismutase Tissue Distribution Xenobiotics algae Chasmagnathus granulata Chlorophyta Decapoda (Crustacea) Parachlorella kessleri Chaufan, Rosa Gabriela Juárez, Angela Beatriz Ithuralde, Raul Esteban Sabatini, Sebastián Eduardo Genovese, Griselda Kesten, Eva Marta Ríos de Molina, María del Carmen Toxicity of hexachlorobenzene and its transference from microalgae (Chlorella kessleri) to crabs (Chasmagnathus granulatus)
topic_facet	Chasmagnathus granulatus Chlorella kessleri Hexachlorobenzene Oxidative stress Uroporphyrinogen decarboxylase glutathione hexachlorobenzene lipid malonaldehyde superoxide dismutase uroporphyrinogen decarboxylase animal cell animal experiment animal tissue antioxidant activity article bioaccumulation chasmagnathus granulatus Chlorella kessleri controlled study crab down regulation enzyme activity epithelium estuary evaluation green alga hepatopancreas histology lipid peroxidation liver injury male measurement morphometrics nonhuman oxidative stress pancreas injury priority journal sea pollution toxicology transference Animals Antioxidants Brachyura Chlorella Epithelium Food Chain Glutathione Hepatopancreas Hexachlorobenzene Lipid Peroxidation Malondialdehyde Superoxide Dismutase Tissue Distribution Xenobiotics algae Chasmagnathus granulata Chlorophyta Decapoda (Crustacea) Parachlorella kessleri
description	The aim of this work was to study the transference of hexachlorobenzene from a green alga (Chlorella kessleri) to an estuary crab (Chasmagnathus granulatus), and to analyze the toxic effects that the xenobiotic has on the latter. The effect of hexachlorobenzene uptake was evaluated measuring oxidative stress, Uroporphyrinogen decarboxylase activity and morphometric parameter alteration, and also performing a histological analysis of crab hepatopancreas. Results demonstrated that hexachlorobenzene enters the alga, is accumulated in it, and then transferred into the crab, causing a decrease in Uroporphyrinogen decarboxylase activity in both organisms. The high malondialdehyde levels detected in crab hepatopancreas after the toxic treatment suggested the existence of hexachlorobenzene-induced lipid peroxidation. Antioxidant defenses such as superoxide dismutase activity and reduced glutathione content fell below normal values on the fourth week of treatment. At the same time, the hepatosomatic index, used as a morphometric parameter, reduced 20% with respect to the control. The histological analysis revealed epithelium disorganization in hepatopancreas tubules, confirming the existence of structural damage caused by hexachlorobenzene. © 2006 Elsevier Ireland Ltd. All rights reserved.
author	Chaufan, Rosa Gabriela Juárez, Angela Beatriz Ithuralde, Raul Esteban Sabatini, Sebastián Eduardo Genovese, Griselda Kesten, Eva Marta Ríos de Molina, María del Carmen
author_facet	Chaufan, Rosa Gabriela Juárez, Angela Beatriz Ithuralde, Raul Esteban Sabatini, Sebastián Eduardo Genovese, Griselda Kesten, Eva Marta Ríos de Molina, María del Carmen
author_sort	Chaufan, Rosa Gabriela
title	Toxicity of hexachlorobenzene and its transference from microalgae (Chlorella kessleri) to crabs (Chasmagnathus granulatus)
title_short	Toxicity of hexachlorobenzene and its transference from microalgae (Chlorella kessleri) to crabs (Chasmagnathus granulatus)
title_full	Toxicity of hexachlorobenzene and its transference from microalgae (Chlorella kessleri) to crabs (Chasmagnathus granulatus)
title_fullStr	Toxicity of hexachlorobenzene and its transference from microalgae (Chlorella kessleri) to crabs (Chasmagnathus granulatus)
title_full_unstemmed	Toxicity of hexachlorobenzene and its transference from microalgae (Chlorella kessleri) to crabs (Chasmagnathus granulatus)
title_sort	toxicity of hexachlorobenzene and its transference from microalgae (chlorella kessleri) to crabs (chasmagnathus granulatus)
publishDate	2006
url	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0300483X_v227_n3_p262_Chaufan http://hdl.handle.net/20.500.12110/paper_0300483X_v227_n3_p262_Chaufan
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Toxicity of hexachlorobenzene and its transference from microalgae (Chlorella kessleri) to crabs (Chasmagnathus granulatus)

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