Inhibition of growth and ochratoxin A biosynthesis in Aspergillus carbonarius by flavonoid and nonflavonoid compounds
The effect of naturally occurring phenolic compounds on Aspergillus carbonarius growth and ochratoxin A (OTA) production was studied. Caffeic acid and the flavonoids, rutin and quercetin, were added to Czapek Yeast Extract agar at concentrations ranging between 50 and 500 mg/l. All phenolic compound...
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2009
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paper:paper_01787888_v25_n3_p165_Romero2023-06-08T15:19:23Z Inhibition of growth and ochratoxin A biosynthesis in Aspergillus carbonarius by flavonoid and nonflavonoid compounds Vaamonde, Graciela Antifungal activity Aspergillus carbonarius Caffeic acid Ochratoxin A Quercetin Rutin caffeic acid flavonoid fungicide ochratoxin phenol derivative quercetin rutoside article Aspergillus aspergillus carbonarius biosynthesis fungus growth growth inhibition growth rate nonhuman statistical analysis toxin synthesis yeast Aspergillus carbonarius The effect of naturally occurring phenolic compounds on Aspergillus carbonarius growth and ochratoxin A (OTA) production was studied. Caffeic acid and the flavonoids, rutin and quercetin, were added to Czapek Yeast Extract agar at concentrations ranging between 50 and 500 mg/l. All phenolic compounds had a significant influence on growth rate and lag phase of A. carbonarius at 250 mg/l. The growth was completely inhibited with 500 mg/l. In comparison with the control, a significant decrease in OTA production was observed with all phenolic compounds. In general, effect on growth was less evident than effect on toxin production. An inhibitory effect on growth and OTA production, as concentration was increased was observed in all cases. The response of A. carbonarius to the flavonoids, rutin and quercetin, was similar. The inhibitory effect of these natural phenolic compounds on fungal growth and OTA production could be an alternative to the use of chemical fungicides. © 2009 Society for Mycotoxin Research and Springer. Fil:Vaamonde, G. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 2009 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01787888_v25_n3_p165_Romero http://hdl.handle.net/20.500.12110/paper_01787888_v25_n3_p165_Romero |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Antifungal activity Aspergillus carbonarius Caffeic acid Ochratoxin A Quercetin Rutin caffeic acid flavonoid fungicide ochratoxin phenol derivative quercetin rutoside article Aspergillus aspergillus carbonarius biosynthesis fungus growth growth inhibition growth rate nonhuman statistical analysis toxin synthesis yeast Aspergillus carbonarius |
| spellingShingle |
Antifungal activity Aspergillus carbonarius Caffeic acid Ochratoxin A Quercetin Rutin caffeic acid flavonoid fungicide ochratoxin phenol derivative quercetin rutoside article Aspergillus aspergillus carbonarius biosynthesis fungus growth growth inhibition growth rate nonhuman statistical analysis toxin synthesis yeast Aspergillus carbonarius Vaamonde, Graciela Inhibition of growth and ochratoxin A biosynthesis in Aspergillus carbonarius by flavonoid and nonflavonoid compounds |
| topic_facet |
Antifungal activity Aspergillus carbonarius Caffeic acid Ochratoxin A Quercetin Rutin caffeic acid flavonoid fungicide ochratoxin phenol derivative quercetin rutoside article Aspergillus aspergillus carbonarius biosynthesis fungus growth growth inhibition growth rate nonhuman statistical analysis toxin synthesis yeast Aspergillus carbonarius |
| description |
The effect of naturally occurring phenolic compounds on Aspergillus carbonarius growth and ochratoxin A (OTA) production was studied. Caffeic acid and the flavonoids, rutin and quercetin, were added to Czapek Yeast Extract agar at concentrations ranging between 50 and 500 mg/l. All phenolic compounds had a significant influence on growth rate and lag phase of A. carbonarius at 250 mg/l. The growth was completely inhibited with 500 mg/l. In comparison with the control, a significant decrease in OTA production was observed with all phenolic compounds. In general, effect on growth was less evident than effect on toxin production. An inhibitory effect on growth and OTA production, as concentration was increased was observed in all cases. The response of A. carbonarius to the flavonoids, rutin and quercetin, was similar. The inhibitory effect of these natural phenolic compounds on fungal growth and OTA production could be an alternative to the use of chemical fungicides. © 2009 Society for Mycotoxin Research and Springer. |
| author |
Vaamonde, Graciela |
| author_facet |
Vaamonde, Graciela |
| author_sort |
Vaamonde, Graciela |
| title |
Inhibition of growth and ochratoxin A biosynthesis in Aspergillus carbonarius by flavonoid and nonflavonoid compounds |
| title_short |
Inhibition of growth and ochratoxin A biosynthesis in Aspergillus carbonarius by flavonoid and nonflavonoid compounds |
| title_full |
Inhibition of growth and ochratoxin A biosynthesis in Aspergillus carbonarius by flavonoid and nonflavonoid compounds |
| title_fullStr |
Inhibition of growth and ochratoxin A biosynthesis in Aspergillus carbonarius by flavonoid and nonflavonoid compounds |
| title_full_unstemmed |
Inhibition of growth and ochratoxin A biosynthesis in Aspergillus carbonarius by flavonoid and nonflavonoid compounds |
| title_sort |
inhibition of growth and ochratoxin a biosynthesis in aspergillus carbonarius by flavonoid and nonflavonoid compounds |
| publishDate |
2009 |
| url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01787888_v25_n3_p165_Romero http://hdl.handle.net/20.500.12110/paper_01787888_v25_n3_p165_Romero |
| work_keys_str_mv |
AT vaamondegraciela inhibitionofgrowthandochratoxinabiosynthesisinaspergilluscarbonariusbyflavonoidandnonflavonoidcompounds |
| _version_ |
1768543177309945856 |