Reduced virulence of a Junin virus mutant is associated with restricted multiplication in murine cells
C167, a mutant derived from the XJC13 strain of Junin virus, is highly attenuated in its pathogenic properties for newborn mice. Whereas 102 PFU of XJC13 injected intracerebrally killed 100% of two-day-old mice, the mutant showed no detectable lethality. Survival of mice infected with C167 was assoc...
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1989
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Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01681702_v13_n4_p283_Scolaro http://hdl.handle.net/20.500.12110/paper_01681702_v13_n4_p283_Scolaro |
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