Genomic and membrane actions of progesterone: Implications for reproductive physiology and behavior
Progesterone, produced by the ovaries and adrenal glands, regulates reproductive behavior and the surge of luteinizing hormone which precedes ovulation by acting on neurons located in different parts of the hypothalamus. The study of the activation of these reproductive functions in female rats has...
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1999
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| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01664328_v105_n1_p37_Schumacher http://hdl.handle.net/20.500.12110/paper_01664328_v105_n1_p37_Schumacher |
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paper:paper_01664328_v105_n1_p37_Schumacher2023-06-08T15:15:43Z Genomic and membrane actions of progesterone: Implications for reproductive physiology and behavior GABA Gonadotropins GT1 cells LH LHRH Lordosis Oxytocin Progesterone 4 aminobutyric acid anxiolytic agent bicuculline corticotropin dactinomycin deoxycorticosterone dopamine receptor estrogen receptor gonadorelin membrane receptor mifepristone mineralocorticoid receptor neuropeptide neurosteroid neurotensin okadaic acid oxytocin oxytocin receptor pregnenolone sulfate progesterone progesterone receptor steroid receptor substance P trilostane vinblastine estrus genetic transcription hormone responsive element hypothalamus lordosis luteinizing hormone release nonhuman priority journal promoter region reproduction review sexual behavior signal transduction Progesterone, produced by the ovaries and adrenal glands, regulates reproductive behavior and the surge of luteinizing hormone which precedes ovulation by acting on neurons located in different parts of the hypothalamus. The study of the activation of these reproductive functions in female rats has allowed to explore the different mechanisms of progesterone action in the brain. It has allowed to demonstrate that new actions of the hormone, which have been observed in particular in vitro systems, are also operational in vivo, and may thus be biologically relevant. This mainly concerns the direct actions of progesterone on receptors of neurotransmitters such as oxytocin and GABA. Activation of the progesterone receptor in the absence of ligand by phosphorylation may also play a role. Copyright (C) 1999 Elsevier Science B.V. 1999 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01664328_v105_n1_p37_Schumacher http://hdl.handle.net/20.500.12110/paper_01664328_v105_n1_p37_Schumacher |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
GABA Gonadotropins GT1 cells LH LHRH Lordosis Oxytocin Progesterone 4 aminobutyric acid anxiolytic agent bicuculline corticotropin dactinomycin deoxycorticosterone dopamine receptor estrogen receptor gonadorelin membrane receptor mifepristone mineralocorticoid receptor neuropeptide neurosteroid neurotensin okadaic acid oxytocin oxytocin receptor pregnenolone sulfate progesterone progesterone receptor steroid receptor substance P trilostane vinblastine estrus genetic transcription hormone responsive element hypothalamus lordosis luteinizing hormone release nonhuman priority journal promoter region reproduction review sexual behavior signal transduction |
| spellingShingle |
GABA Gonadotropins GT1 cells LH LHRH Lordosis Oxytocin Progesterone 4 aminobutyric acid anxiolytic agent bicuculline corticotropin dactinomycin deoxycorticosterone dopamine receptor estrogen receptor gonadorelin membrane receptor mifepristone mineralocorticoid receptor neuropeptide neurosteroid neurotensin okadaic acid oxytocin oxytocin receptor pregnenolone sulfate progesterone progesterone receptor steroid receptor substance P trilostane vinblastine estrus genetic transcription hormone responsive element hypothalamus lordosis luteinizing hormone release nonhuman priority journal promoter region reproduction review sexual behavior signal transduction Genomic and membrane actions of progesterone: Implications for reproductive physiology and behavior |
| topic_facet |
GABA Gonadotropins GT1 cells LH LHRH Lordosis Oxytocin Progesterone 4 aminobutyric acid anxiolytic agent bicuculline corticotropin dactinomycin deoxycorticosterone dopamine receptor estrogen receptor gonadorelin membrane receptor mifepristone mineralocorticoid receptor neuropeptide neurosteroid neurotensin okadaic acid oxytocin oxytocin receptor pregnenolone sulfate progesterone progesterone receptor steroid receptor substance P trilostane vinblastine estrus genetic transcription hormone responsive element hypothalamus lordosis luteinizing hormone release nonhuman priority journal promoter region reproduction review sexual behavior signal transduction |
| description |
Progesterone, produced by the ovaries and adrenal glands, regulates reproductive behavior and the surge of luteinizing hormone which precedes ovulation by acting on neurons located in different parts of the hypothalamus. The study of the activation of these reproductive functions in female rats has allowed to explore the different mechanisms of progesterone action in the brain. It has allowed to demonstrate that new actions of the hormone, which have been observed in particular in vitro systems, are also operational in vivo, and may thus be biologically relevant. This mainly concerns the direct actions of progesterone on receptors of neurotransmitters such as oxytocin and GABA. Activation of the progesterone receptor in the absence of ligand by phosphorylation may also play a role. Copyright (C) 1999 Elsevier Science B.V. |
| title |
Genomic and membrane actions of progesterone: Implications for reproductive physiology and behavior |
| title_short |
Genomic and membrane actions of progesterone: Implications for reproductive physiology and behavior |
| title_full |
Genomic and membrane actions of progesterone: Implications for reproductive physiology and behavior |
| title_fullStr |
Genomic and membrane actions of progesterone: Implications for reproductive physiology and behavior |
| title_full_unstemmed |
Genomic and membrane actions of progesterone: Implications for reproductive physiology and behavior |
| title_sort |
genomic and membrane actions of progesterone: implications for reproductive physiology and behavior |
| publishDate |
1999 |
| url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01664328_v105_n1_p37_Schumacher http://hdl.handle.net/20.500.12110/paper_01664328_v105_n1_p37_Schumacher |
| _version_ |
1768545089762623488 |