5-Methylcoumaranones from Mutisia friesiana and their bioactivity

In addition to the known mutisicoumaranones A (1) and B (2), the methanolic extract of the aerial parts of the shrub Mutisia friesiana afforded two new 5-methylcoumaranones, mutisicoumaranones C (3) and D (4). Their structures were elucidated by spectroscopic methods. 13C NMR data for mutisicoumaran...

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Autor principal:	Maier, Marta Silvia
Publicado:	2004
Materias:	5 methylcoumaranone 5 methylcoumaranone a 5 methylcoumaranone b 5 methylcoumaranone c 5 methylcoumaranone d mutisicoumaranone a mutisicoumaranone b mutisicoumaranone c mutisicoumaranone d plant extract unclassified drug antifungal activity article bactericidal activity carbon nuclear magnetic resonance chemical structure Cladosporium cucumerinum drug activity Mutisia friesiana plant proton nuclear magnetic resonance spectroscopy Staphylococcus aureus structure analysis woody stem Antibiotics, Antifungal Antifungal Agents Argentina Asteraceae Benzofurans Cladosporium Microbial Sensitivity Tests Molecular Structure Nuclear Magnetic Resonance, Biomolecular Plants, Medicinal Fungi Mutisia Staphylococcus
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01633864_v67_n5_p778_Viturro http://hdl.handle.net/20.500.12110/paper_01633864_v67_n5_p778_Viturro
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	paper:paper_01633864_v67_n5_p778_Viturro
record_format	dspace
spelling	paper:paper_01633864_v67_n5_p778_Viturro2023-06-08T15:14:16Z 5-Methylcoumaranones from Mutisia friesiana and their bioactivity Maier, Marta Silvia 5 methylcoumaranone 5 methylcoumaranone a 5 methylcoumaranone b 5 methylcoumaranone c 5 methylcoumaranone d mutisicoumaranone a mutisicoumaranone b mutisicoumaranone c mutisicoumaranone d plant extract unclassified drug antifungal activity article bactericidal activity carbon nuclear magnetic resonance chemical structure Cladosporium cucumerinum drug activity Mutisia friesiana plant proton nuclear magnetic resonance spectroscopy Staphylococcus aureus structure analysis woody stem Antibiotics, Antifungal Antifungal Agents Argentina Asteraceae Benzofurans Cladosporium Microbial Sensitivity Tests Molecular Structure Nuclear Magnetic Resonance, Biomolecular Plants, Medicinal Staphylococcus aureus Cladosporium Cladosporium cucumerinum Fungi Mutisia Staphylococcus Staphylococcus aureus In addition to the known mutisicoumaranones A (1) and B (2), the methanolic extract of the aerial parts of the shrub Mutisia friesiana afforded two new 5-methylcoumaranones, mutisicoumaranones C (3) and D (4). Their structures were elucidated by spectroscopic methods. 13C NMR data for mutisicoumaranones A and B are reported for the first time. All compounds showed antifungal activity against the phytopathogenic fungus Cladosporium cucumerinum and bactericidal activity against Staphylococcus aureus. The presence of 5-methylcoumaranones A-D is biosynthetically related to 5-methylcoumarins and phenolic derivatives previously isolated from M. friesiana. Fil:Maier, M.S. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 2004 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01633864_v67_n5_p778_Viturro http://hdl.handle.net/20.500.12110/paper_01633864_v67_n5_p778_Viturro
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	5 methylcoumaranone 5 methylcoumaranone a 5 methylcoumaranone b 5 methylcoumaranone c 5 methylcoumaranone d mutisicoumaranone a mutisicoumaranone b mutisicoumaranone c mutisicoumaranone d plant extract unclassified drug antifungal activity article bactericidal activity carbon nuclear magnetic resonance chemical structure Cladosporium cucumerinum drug activity Mutisia friesiana plant proton nuclear magnetic resonance spectroscopy Staphylococcus aureus structure analysis woody stem Antibiotics, Antifungal Antifungal Agents Argentina Asteraceae Benzofurans Cladosporium Microbial Sensitivity Tests Molecular Structure Nuclear Magnetic Resonance, Biomolecular Plants, Medicinal Staphylococcus aureus Cladosporium Cladosporium cucumerinum Fungi Mutisia Staphylococcus Staphylococcus aureus
spellingShingle	5 methylcoumaranone 5 methylcoumaranone a 5 methylcoumaranone b 5 methylcoumaranone c 5 methylcoumaranone d mutisicoumaranone a mutisicoumaranone b mutisicoumaranone c mutisicoumaranone d plant extract unclassified drug antifungal activity article bactericidal activity carbon nuclear magnetic resonance chemical structure Cladosporium cucumerinum drug activity Mutisia friesiana plant proton nuclear magnetic resonance spectroscopy Staphylococcus aureus structure analysis woody stem Antibiotics, Antifungal Antifungal Agents Argentina Asteraceae Benzofurans Cladosporium Microbial Sensitivity Tests Molecular Structure Nuclear Magnetic Resonance, Biomolecular Plants, Medicinal Staphylococcus aureus Cladosporium Cladosporium cucumerinum Fungi Mutisia Staphylococcus Staphylococcus aureus Maier, Marta Silvia 5-Methylcoumaranones from Mutisia friesiana and their bioactivity
topic_facet	5 methylcoumaranone 5 methylcoumaranone a 5 methylcoumaranone b 5 methylcoumaranone c 5 methylcoumaranone d mutisicoumaranone a mutisicoumaranone b mutisicoumaranone c mutisicoumaranone d plant extract unclassified drug antifungal activity article bactericidal activity carbon nuclear magnetic resonance chemical structure Cladosporium cucumerinum drug activity Mutisia friesiana plant proton nuclear magnetic resonance spectroscopy Staphylococcus aureus structure analysis woody stem Antibiotics, Antifungal Antifungal Agents Argentina Asteraceae Benzofurans Cladosporium Microbial Sensitivity Tests Molecular Structure Nuclear Magnetic Resonance, Biomolecular Plants, Medicinal Staphylococcus aureus Cladosporium Cladosporium cucumerinum Fungi Mutisia Staphylococcus Staphylococcus aureus
description	In addition to the known mutisicoumaranones A (1) and B (2), the methanolic extract of the aerial parts of the shrub Mutisia friesiana afforded two new 5-methylcoumaranones, mutisicoumaranones C (3) and D (4). Their structures were elucidated by spectroscopic methods. 13C NMR data for mutisicoumaranones A and B are reported for the first time. All compounds showed antifungal activity against the phytopathogenic fungus Cladosporium cucumerinum and bactericidal activity against Staphylococcus aureus. The presence of 5-methylcoumaranones A-D is biosynthetically related to 5-methylcoumarins and phenolic derivatives previously isolated from M. friesiana.
author	Maier, Marta Silvia
author_facet	Maier, Marta Silvia
author_sort	Maier, Marta Silvia
title	5-Methylcoumaranones from Mutisia friesiana and their bioactivity
title_short	5-Methylcoumaranones from Mutisia friesiana and their bioactivity
title_full	5-Methylcoumaranones from Mutisia friesiana and their bioactivity
title_fullStr	5-Methylcoumaranones from Mutisia friesiana and their bioactivity
title_full_unstemmed	5-Methylcoumaranones from Mutisia friesiana and their bioactivity
title_sort	5-methylcoumaranones from mutisia friesiana and their bioactivity
publishDate	2004
url	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01633864_v67_n5_p778_Viturro http://hdl.handle.net/20.500.12110/paper_01633864_v67_n5_p778_Viturro
work_keys_str_mv	AT maiermartasilvia 5methylcoumaranonesfrommutisiafriesianaandtheirbioactivity
_version_	1768544726186721280

5-Methylcoumaranones from Mutisia friesiana and their bioactivity

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