7-Hydroxywithanolides from Datura ferox

Three new withanolides were isolated from leaves of Datura ferox. Their structures were established as (17R,20S,22R)-5α,6α,7β,12α-tetrahydroxy- 1-oxowitha-2,24-dienolide (1), (17R,20S,22R,24S,25S)-24,25-epoxy- 5α,6α,7β,12α-tetrahydroxy-1-oxowitha-2-enolide (2), and (17R,20S,22R)- 5α,6α-epoxy-7α-hydr...

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Detalles Bibliográficos
Autores principales: Veleiro, Adriana Silvia, Cirigliano, Adriana Mónica, Burton, Gerardo
Publicado: 1999
Materias:
withanolide
article
drug isolation
drug structure
mass spectrometry
molecular model
nonhuman
nuclear magnetic resonance
plant leaf
Datura ferox
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01633864_v62_n7_p1010_Veleiro
http://hdl.handle.net/20.500.12110/paper_01633864_v62_n7_p1010_Veleiro
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
id paper:paper_01633864_v62_n7_p1010_Veleiro
record_format dspace
spelling paper:paper_01633864_v62_n7_p1010_Veleiro2023-06-08T15:14:12Z 7-Hydroxywithanolides from Datura ferox Veleiro, Adriana Silvia Cirigliano, Adriana Mónica Burton, Gerardo withanolide article drug isolation drug structure mass spectrometry molecular model nonhuman nuclear magnetic resonance plant leaf Datura ferox Three new withanolides were isolated from leaves of Datura ferox. Their structures were established as (17R,20S,22R)-5α,6α,7β,12α-tetrahydroxy- 1-oxowitha-2,24-dienolide (1), (17R,20S,22R,24S,25S)-24,25-epoxy- 5α,6α,7β,12α-tetrahydroxy-1-oxowitha-2-enolide (2), and (17R,20S,22R)- 5α,6α-epoxy-7α-hydroxy-1,12-dioxowitha-2,24-dienolide (3), using spectroscopic methods (NMR, MS) and molecular modeling. Fil:Veleiro, A.S. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Cirigliano, A.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Burton, G. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 1999 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01633864_v62_n7_p1010_Veleiro http://hdl.handle.net/20.500.12110/paper_01633864_v62_n7_p1010_Veleiro
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic withanolide
article
drug isolation
drug structure
mass spectrometry
molecular model
nonhuman
nuclear magnetic resonance
plant leaf
Datura ferox
spellingShingle withanolide
article
drug isolation
drug structure
mass spectrometry
molecular model
nonhuman
nuclear magnetic resonance
plant leaf
Datura ferox
Veleiro, Adriana Silvia
Cirigliano, Adriana Mónica
Burton, Gerardo
7-Hydroxywithanolides from Datura ferox
topic_facet withanolide
article
drug isolation
drug structure
mass spectrometry
molecular model
nonhuman
nuclear magnetic resonance
plant leaf
Datura ferox
description Three new withanolides were isolated from leaves of Datura ferox. Their structures were established as (17R,20S,22R)-5α,6α,7β,12α-tetrahydroxy- 1-oxowitha-2,24-dienolide (1), (17R,20S,22R,24S,25S)-24,25-epoxy- 5α,6α,7β,12α-tetrahydroxy-1-oxowitha-2-enolide (2), and (17R,20S,22R)- 5α,6α-epoxy-7α-hydroxy-1,12-dioxowitha-2,24-dienolide (3), using spectroscopic methods (NMR, MS) and molecular modeling.
author Veleiro, Adriana Silvia
Cirigliano, Adriana Mónica
Burton, Gerardo
author_facet Veleiro, Adriana Silvia
Cirigliano, Adriana Mónica
Burton, Gerardo
author_sort Veleiro, Adriana Silvia
title 7-Hydroxywithanolides from Datura ferox
title_short 7-Hydroxywithanolides from Datura ferox
title_full 7-Hydroxywithanolides from Datura ferox
title_fullStr 7-Hydroxywithanolides from Datura ferox
title_full_unstemmed 7-Hydroxywithanolides from Datura ferox
title_sort 7-hydroxywithanolides from datura ferox
publishDate 1999
url https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01633864_v62_n7_p1010_Veleiro
http://hdl.handle.net/20.500.12110/paper_01633864_v62_n7_p1010_Veleiro
work_keys_str_mv AT veleiroadrianasilvia 7hydroxywithanolidesfromdaturaferox
AT ciriglianoadrianamonica 7hydroxywithanolidesfromdaturaferox
AT burtongerardo 7hydroxywithanolidesfromdaturaferox
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