New hydroxylated withanolides from Salpichroa origanifolia

From the leaves of Salpichroa origanifolia three new withanolides, (20S,22R,24S,25S,26R)-5α,6α:22,26:24,25-triepoxy-15,26-dihydroxy- 17(13→18)-abeo-ergosta-2,13,15,17-tetraen-1-one (salpichrolide G, 1), (20S,22R,24S,25R)-5α,6α:22,26-diepoxy-24,25,26-trihydroxy-17(13→18)-abeo- ergosta-2,13,15,17-tetr...

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Detalles Bibliográficos
Autores principales:	Tettamanzi, María Cristina, Veleiro, Adriana Silvia, Burton, Gerardo
Publicado:	1998
Materias:	salpichrolide g salpichrolide h salpichrolide i unclassified drug withanolide article carbon nuclear magnetic resonance chemical structure hydroxylation molecular model nuclear Overhauser effect plant leaf proton nuclear magnetic resonance spectroscopy stereochemistry Salpichroa origanifolia
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01633864_v61_n3_p338_Tettamanzi http://hdl.handle.net/20.500.12110/paper_01633864_v61_n3_p338_Tettamanzi
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	paper:paper_01633864_v61_n3_p338_Tettamanzi
record_format	dspace
spelling	paper:paper_01633864_v61_n3_p338_Tettamanzi2023-06-08T15:14:11Z New hydroxylated withanolides from Salpichroa origanifolia Tettamanzi, María Cristina Veleiro, Adriana Silvia Burton, Gerardo salpichrolide g salpichrolide h salpichrolide i unclassified drug withanolide article carbon nuclear magnetic resonance chemical structure hydroxylation molecular model nuclear Overhauser effect plant leaf proton nuclear magnetic resonance spectroscopy stereochemistry Salpichroa origanifolia From the leaves of Salpichroa origanifolia three new withanolides, (20S,22R,24S,25S,26R)-5α,6α:22,26:24,25-triepoxy-15,26-dihydroxy- 17(13→18)-abeo-ergosta-2,13,15,17-tetraen-1-one (salpichrolide G, 1), (20S,22R,24S,25R)-5α,6α:22,26-diepoxy-24,25,26-trihydroxy-17(13→18)-abeo- ergosta-2,13,15,17-tetraen-1-one (salpichrolide H, 2), and (20S,22R,25S)- 5α,6α:22,26-diepoxy-25,26-dihydroxy-17(13→18)-abeo-ergosta-2,13,15,17,23- pentaen-1-one (salpichrolide I, 3), were isolated and characterized by spectroscopic methods and with the aid of molecular modeling. The latter two compounds were obtained as an epimeric mixture at C-26. Fil:Tettamanzi, M.C. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Veleiro, A.S. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Burton, G. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 1998 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01633864_v61_n3_p338_Tettamanzi http://hdl.handle.net/20.500.12110/paper_01633864_v61_n3_p338_Tettamanzi
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	salpichrolide g salpichrolide h salpichrolide i unclassified drug withanolide article carbon nuclear magnetic resonance chemical structure hydroxylation molecular model nuclear Overhauser effect plant leaf proton nuclear magnetic resonance spectroscopy stereochemistry Salpichroa origanifolia
spellingShingle	salpichrolide g salpichrolide h salpichrolide i unclassified drug withanolide article carbon nuclear magnetic resonance chemical structure hydroxylation molecular model nuclear Overhauser effect plant leaf proton nuclear magnetic resonance spectroscopy stereochemistry Salpichroa origanifolia Tettamanzi, María Cristina Veleiro, Adriana Silvia Burton, Gerardo New hydroxylated withanolides from Salpichroa origanifolia
topic_facet	salpichrolide g salpichrolide h salpichrolide i unclassified drug withanolide article carbon nuclear magnetic resonance chemical structure hydroxylation molecular model nuclear Overhauser effect plant leaf proton nuclear magnetic resonance spectroscopy stereochemistry Salpichroa origanifolia
description	From the leaves of Salpichroa origanifolia three new withanolides, (20S,22R,24S,25S,26R)-5α,6α:22,26:24,25-triepoxy-15,26-dihydroxy- 17(13→18)-abeo-ergosta-2,13,15,17-tetraen-1-one (salpichrolide G, 1), (20S,22R,24S,25R)-5α,6α:22,26-diepoxy-24,25,26-trihydroxy-17(13→18)-abeo- ergosta-2,13,15,17-tetraen-1-one (salpichrolide H, 2), and (20S,22R,25S)- 5α,6α:22,26-diepoxy-25,26-dihydroxy-17(13→18)-abeo-ergosta-2,13,15,17,23- pentaen-1-one (salpichrolide I, 3), were isolated and characterized by spectroscopic methods and with the aid of molecular modeling. The latter two compounds were obtained as an epimeric mixture at C-26.
author	Tettamanzi, María Cristina Veleiro, Adriana Silvia Burton, Gerardo
author_facet	Tettamanzi, María Cristina Veleiro, Adriana Silvia Burton, Gerardo
author_sort	Tettamanzi, María Cristina
title	New hydroxylated withanolides from Salpichroa origanifolia
title_short	New hydroxylated withanolides from Salpichroa origanifolia
title_full	New hydroxylated withanolides from Salpichroa origanifolia
title_fullStr	New hydroxylated withanolides from Salpichroa origanifolia
title_full_unstemmed	New hydroxylated withanolides from Salpichroa origanifolia
title_sort	new hydroxylated withanolides from salpichroa origanifolia
publishDate	1998
url	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01633864_v61_n3_p338_Tettamanzi http://hdl.handle.net/20.500.12110/paper_01633864_v61_n3_p338_Tettamanzi
work_keys_str_mv	AT tettamanzimariacristina newhydroxylatedwithanolidesfromsalpichroaoriganifolia AT veleiroadrianasilvia newhydroxylatedwithanolidesfromsalpichroaoriganifolia AT burtongerardo newhydroxylatedwithanolidesfromsalpichroaoriganifolia
_version_	1768545641856761856

New hydroxylated withanolides from Salpichroa origanifolia

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