Mouse Embryo Compaction
Compaction is a critical first morphological event in the preimplantation development of the mammalian embryo. Characterized by the transformation of the embryo from a loose cluster of spherical cells into a tightly packed mass, compaction is a key step in the establishment of the first tissue-like...
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2016
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| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00702153_v120_n_p235_White http://hdl.handle.net/20.500.12110/paper_00702153_v120_n_p235_White |
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paper:paper_00702153_v120_n_p235_White |
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paper:paper_00702153_v120_n_p235_White2023-06-08T15:06:21Z Mouse Embryo Compaction Cell polarity Cell shape Compaction Mouse embryo Preimplantation animal cell division cell lineage cell shape cytology embryo development mammalian embryo mouse Animals Cell Division Cell Lineage Cell Shape Embryo, Mammalian Embryonic Development Mice Compaction is a critical first morphological event in the preimplantation development of the mammalian embryo. Characterized by the transformation of the embryo from a loose cluster of spherical cells into a tightly packed mass, compaction is a key step in the establishment of the first tissue-like structures of the embryo. Although early investigation of the mechanisms driving compaction implicated changes in cell–cell adhesion, recent work has identified essential roles for cortical tension and a compaction-specific class of filopodia. During the transition from 8 to 16 cells, as the embryo is compacting, it must also make fundamental decisions regarding cell position, polarity, and fate. Understanding how these and other processes are integrated with compaction requires further investigation. Emerging imaging-based techniques that enable quantitative analysis from the level of cell–cell interactions down to the level of individual regulatory molecules will provide a greater understanding of how compaction shapes the early mammalian embryo. © 2016 Elsevier Inc. 2016 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00702153_v120_n_p235_White http://hdl.handle.net/20.500.12110/paper_00702153_v120_n_p235_White |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Cell polarity Cell shape Compaction Mouse embryo Preimplantation animal cell division cell lineage cell shape cytology embryo development mammalian embryo mouse Animals Cell Division Cell Lineage Cell Shape Embryo, Mammalian Embryonic Development Mice |
| spellingShingle |
Cell polarity Cell shape Compaction Mouse embryo Preimplantation animal cell division cell lineage cell shape cytology embryo development mammalian embryo mouse Animals Cell Division Cell Lineage Cell Shape Embryo, Mammalian Embryonic Development Mice Mouse Embryo Compaction |
| topic_facet |
Cell polarity Cell shape Compaction Mouse embryo Preimplantation animal cell division cell lineage cell shape cytology embryo development mammalian embryo mouse Animals Cell Division Cell Lineage Cell Shape Embryo, Mammalian Embryonic Development Mice |
| description |
Compaction is a critical first morphological event in the preimplantation development of the mammalian embryo. Characterized by the transformation of the embryo from a loose cluster of spherical cells into a tightly packed mass, compaction is a key step in the establishment of the first tissue-like structures of the embryo. Although early investigation of the mechanisms driving compaction implicated changes in cell–cell adhesion, recent work has identified essential roles for cortical tension and a compaction-specific class of filopodia. During the transition from 8 to 16 cells, as the embryo is compacting, it must also make fundamental decisions regarding cell position, polarity, and fate. Understanding how these and other processes are integrated with compaction requires further investigation. Emerging imaging-based techniques that enable quantitative analysis from the level of cell–cell interactions down to the level of individual regulatory molecules will provide a greater understanding of how compaction shapes the early mammalian embryo. © 2016 Elsevier Inc. |
| title |
Mouse Embryo Compaction |
| title_short |
Mouse Embryo Compaction |
| title_full |
Mouse Embryo Compaction |
| title_fullStr |
Mouse Embryo Compaction |
| title_full_unstemmed |
Mouse Embryo Compaction |
| title_sort |
mouse embryo compaction |
| publishDate |
2016 |
| url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00702153_v120_n_p235_White http://hdl.handle.net/20.500.12110/paper_00702153_v120_n_p235_White |
| _version_ |
1768541648595189760 |