Prostaglandin F2α (PGF2α) triggers Protein Kinase C (PKC) and tyrosine kinase activity in cultured mammalian cells
Prostaglandin F2α (PGF2α) added to confluent resting Swiss 3T3 cells triggers tyrosine kinase (PTK) activation characterized by the phosphorylation of a set of 75, 86, 110 and 140 kD proteins. PGF2α induces this event independently of PKC activation. However, both PKC and PTK activities appear to ac...
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1997
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| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00652598_v400_nA_p531_JimenezDeAsua http://hdl.handle.net/20.500.12110/paper_00652598_v400_nA_p531_JimenezDeAsua |
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paper:paper_00652598_v400_nA_p531_JimenezDeAsua |
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paper:paper_00652598_v400_nA_p531_JimenezDeAsua2023-06-08T15:06:00Z Prostaglandin F2α (PGF2α) triggers Protein Kinase C (PKC) and tyrosine kinase activity in cultured mammalian cells prostaglandin f2 alpha protein kinase c protein tyrosine kinase insulin phorbol 13 acetate 12 myristate prostaglandin E1 prostaglandin F2 alpha protein kinase C animal cell cell culture cell division cell proliferation conference paper dna synthesis enzyme activation enzyme activity mammal mitogenesis mitosis nonhuman priority journal protein phosphorylation signal transduction animal article biological model cell division cell strain 3T3 DNA replication drug effect kinetics metabolism mouse phosphorylation Animalia Mammalia 3T3 Cells Alprostadil Animals Cell Division Dinoprost DNA Replication Enzyme Activation Insulin Kinetics Mice Models, Biological Phosphorylation Protein Kinase C Protein-Tyrosine Kinases Tetradecanoylphorbol Acetate Prostaglandin F2α (PGF2α) added to confluent resting Swiss 3T3 cells triggers tyrosine kinase (PTK) activation characterized by the phosphorylation of a set of 75, 86, 110 and 140 kD proteins. PGF2α induces this event independently of PKC activation. However, both PKC and PTK activities appear to act concertedly to cause mitogenesis. Here we discuss their relevance in the control of mammalian cell division. 1997 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00652598_v400_nA_p531_JimenezDeAsua http://hdl.handle.net/20.500.12110/paper_00652598_v400_nA_p531_JimenezDeAsua |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
prostaglandin f2 alpha protein kinase c protein tyrosine kinase insulin phorbol 13 acetate 12 myristate prostaglandin E1 prostaglandin F2 alpha protein kinase C animal cell cell culture cell division cell proliferation conference paper dna synthesis enzyme activation enzyme activity mammal mitogenesis mitosis nonhuman priority journal protein phosphorylation signal transduction animal article biological model cell division cell strain 3T3 DNA replication drug effect kinetics metabolism mouse phosphorylation Animalia Mammalia 3T3 Cells Alprostadil Animals Cell Division Dinoprost DNA Replication Enzyme Activation Insulin Kinetics Mice Models, Biological Phosphorylation Protein Kinase C Protein-Tyrosine Kinases Tetradecanoylphorbol Acetate |
| spellingShingle |
prostaglandin f2 alpha protein kinase c protein tyrosine kinase insulin phorbol 13 acetate 12 myristate prostaglandin E1 prostaglandin F2 alpha protein kinase C animal cell cell culture cell division cell proliferation conference paper dna synthesis enzyme activation enzyme activity mammal mitogenesis mitosis nonhuman priority journal protein phosphorylation signal transduction animal article biological model cell division cell strain 3T3 DNA replication drug effect kinetics metabolism mouse phosphorylation Animalia Mammalia 3T3 Cells Alprostadil Animals Cell Division Dinoprost DNA Replication Enzyme Activation Insulin Kinetics Mice Models, Biological Phosphorylation Protein Kinase C Protein-Tyrosine Kinases Tetradecanoylphorbol Acetate Prostaglandin F2α (PGF2α) triggers Protein Kinase C (PKC) and tyrosine kinase activity in cultured mammalian cells |
| topic_facet |
prostaglandin f2 alpha protein kinase c protein tyrosine kinase insulin phorbol 13 acetate 12 myristate prostaglandin E1 prostaglandin F2 alpha protein kinase C animal cell cell culture cell division cell proliferation conference paper dna synthesis enzyme activation enzyme activity mammal mitogenesis mitosis nonhuman priority journal protein phosphorylation signal transduction animal article biological model cell division cell strain 3T3 DNA replication drug effect kinetics metabolism mouse phosphorylation Animalia Mammalia 3T3 Cells Alprostadil Animals Cell Division Dinoprost DNA Replication Enzyme Activation Insulin Kinetics Mice Models, Biological Phosphorylation Protein Kinase C Protein-Tyrosine Kinases Tetradecanoylphorbol Acetate |
| description |
Prostaglandin F2α (PGF2α) added to confluent resting Swiss 3T3 cells triggers tyrosine kinase (PTK) activation characterized by the phosphorylation of a set of 75, 86, 110 and 140 kD proteins. PGF2α induces this event independently of PKC activation. However, both PKC and PTK activities appear to act concertedly to cause mitogenesis. Here we discuss their relevance in the control of mammalian cell division. |
| title |
Prostaglandin F2α (PGF2α) triggers Protein Kinase C (PKC) and tyrosine kinase activity in cultured mammalian cells |
| title_short |
Prostaglandin F2α (PGF2α) triggers Protein Kinase C (PKC) and tyrosine kinase activity in cultured mammalian cells |
| title_full |
Prostaglandin F2α (PGF2α) triggers Protein Kinase C (PKC) and tyrosine kinase activity in cultured mammalian cells |
| title_fullStr |
Prostaglandin F2α (PGF2α) triggers Protein Kinase C (PKC) and tyrosine kinase activity in cultured mammalian cells |
| title_full_unstemmed |
Prostaglandin F2α (PGF2α) triggers Protein Kinase C (PKC) and tyrosine kinase activity in cultured mammalian cells |
| title_sort |
prostaglandin f2α (pgf2α) triggers protein kinase c (pkc) and tyrosine kinase activity in cultured mammalian cells |
| publishDate |
1997 |
| url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00652598_v400_nA_p531_JimenezDeAsua http://hdl.handle.net/20.500.12110/paper_00652598_v400_nA_p531_JimenezDeAsua |
| _version_ |
1768546389743108096 |