Cyclic oligomers (macroaldonolactones) from a protected d-galactonic acid monomer
Dicyclohexylcarbodiimide-promoted self-condensation of 2,3:4,5-di-O-isopropylidene-d-galactonic acid (3) led to the macrocyclic oligomeric cyclo[(2,3:4,5-di-O-isopropylidene-(1→6)-d-galactonate)2 ] (4) and cyclo[(2,3:4,5-di-O-isopropylidene-(1→6)-d-galactonate)3 ] (5), having, respectively, 14- and...
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2009
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| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00404039_v50_n40_p5677_LorenaRomeroZaliz http://hdl.handle.net/20.500.12110/paper_00404039_v50_n40_p5677_LorenaRomeroZaliz |
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paper:paper_00404039_v50_n40_p5677_LorenaRomeroZaliz2023-06-08T15:04:28Z Cyclic oligomers (macroaldonolactones) from a protected d-galactonic acid monomer Aldonic acid Biomaterial Cyclodextrin Macrocycle Macrolactone 2,3:4,5 di o isopropylidene dextro galactonic acid biomaterial cyclo[(2,3:4,5 di o isopropylidene 2(1-6) dextro galactonate)] cyclo[(2,3:4,5 di o isopropylidene 3(1-6) dextro galactonate)] cyclodextrin galactonic acid lactone derivative macroaldonolactone derivative macrocyclic compound oligomer unclassified drug article cyclization dimerization oligomerization proton nuclear magnetic resonance reaction analysis synthesis Dicyclohexylcarbodiimide-promoted self-condensation of 2,3:4,5-di-O-isopropylidene-d-galactonic acid (3) led to the macrocyclic oligomeric cyclo[(2,3:4,5-di-O-isopropylidene-(1→6)-d-galactonate)2 ] (4) and cyclo[(2,3:4,5-di-O-isopropylidene-(1→6)-d-galactonate)3 ] (5), having, respectively, 14- and 21-membered rings. The macrocycles 4 and 5 were also synthesized by cyclization of the respective linear dimer 11 and trimer 14 ω-hydroxy acids precursors prepared by stepwise additions of 3. Compounds 4 and 5 are biomaterials that may be described as macrolactone-cyclodextrins. © 2009 Elsevier Ltd. All rights reserved. 2009 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00404039_v50_n40_p5677_LorenaRomeroZaliz http://hdl.handle.net/20.500.12110/paper_00404039_v50_n40_p5677_LorenaRomeroZaliz |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Aldonic acid Biomaterial Cyclodextrin Macrocycle Macrolactone 2,3:4,5 di o isopropylidene dextro galactonic acid biomaterial cyclo[(2,3:4,5 di o isopropylidene 2(1-6) dextro galactonate)] cyclo[(2,3:4,5 di o isopropylidene 3(1-6) dextro galactonate)] cyclodextrin galactonic acid lactone derivative macroaldonolactone derivative macrocyclic compound oligomer unclassified drug article cyclization dimerization oligomerization proton nuclear magnetic resonance reaction analysis synthesis |
| spellingShingle |
Aldonic acid Biomaterial Cyclodextrin Macrocycle Macrolactone 2,3:4,5 di o isopropylidene dextro galactonic acid biomaterial cyclo[(2,3:4,5 di o isopropylidene 2(1-6) dextro galactonate)] cyclo[(2,3:4,5 di o isopropylidene 3(1-6) dextro galactonate)] cyclodextrin galactonic acid lactone derivative macroaldonolactone derivative macrocyclic compound oligomer unclassified drug article cyclization dimerization oligomerization proton nuclear magnetic resonance reaction analysis synthesis Cyclic oligomers (macroaldonolactones) from a protected d-galactonic acid monomer |
| topic_facet |
Aldonic acid Biomaterial Cyclodextrin Macrocycle Macrolactone 2,3:4,5 di o isopropylidene dextro galactonic acid biomaterial cyclo[(2,3:4,5 di o isopropylidene 2(1-6) dextro galactonate)] cyclo[(2,3:4,5 di o isopropylidene 3(1-6) dextro galactonate)] cyclodextrin galactonic acid lactone derivative macroaldonolactone derivative macrocyclic compound oligomer unclassified drug article cyclization dimerization oligomerization proton nuclear magnetic resonance reaction analysis synthesis |
| description |
Dicyclohexylcarbodiimide-promoted self-condensation of 2,3:4,5-di-O-isopropylidene-d-galactonic acid (3) led to the macrocyclic oligomeric cyclo[(2,3:4,5-di-O-isopropylidene-(1→6)-d-galactonate)2 ] (4) and cyclo[(2,3:4,5-di-O-isopropylidene-(1→6)-d-galactonate)3 ] (5), having, respectively, 14- and 21-membered rings. The macrocycles 4 and 5 were also synthesized by cyclization of the respective linear dimer 11 and trimer 14 ω-hydroxy acids precursors prepared by stepwise additions of 3. Compounds 4 and 5 are biomaterials that may be described as macrolactone-cyclodextrins. © 2009 Elsevier Ltd. All rights reserved. |
| title |
Cyclic oligomers (macroaldonolactones) from a protected d-galactonic acid monomer |
| title_short |
Cyclic oligomers (macroaldonolactones) from a protected d-galactonic acid monomer |
| title_full |
Cyclic oligomers (macroaldonolactones) from a protected d-galactonic acid monomer |
| title_fullStr |
Cyclic oligomers (macroaldonolactones) from a protected d-galactonic acid monomer |
| title_full_unstemmed |
Cyclic oligomers (macroaldonolactones) from a protected d-galactonic acid monomer |
| title_sort |
cyclic oligomers (macroaldonolactones) from a protected d-galactonic acid monomer |
| publishDate |
2009 |
| url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00404039_v50_n40_p5677_LorenaRomeroZaliz http://hdl.handle.net/20.500.12110/paper_00404039_v50_n40_p5677_LorenaRomeroZaliz |
| _version_ |
1768543792560865280 |