Reactions of per-O-benzoyl-β-D-galf isothiocyanate, a chiral resolving agent

Tetra-O-benzoyl-β-D-galactofuranosyl isothiocyanate (1) was readily prepared (90% yield) from per-O-benzoyl-D-galactofuranose, via the glycosyl bromide. Reaction of 1 with alcohols, amines and amino acids afforded a variety of glycosylthiourethanes and glycosylthioureides. The isothiocyanate 1 showe...

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Detalles Bibliográficos
Autores principales:	Marino, María Carla, Varela, Oscar José, Muchnik de Lederkremer, Rosa María
Publicado:	1997
Materias:	isothiocyanic acid derivative tetra o benzoyl beta galactofuranosylisothiocyanate unclassified drug antifungal activity antimicrobial activity article drug conformation priority journal stereochemistry structure activity relation
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00404020_v53_n47_p16009_Marino http://hdl.handle.net/20.500.12110/paper_00404020_v53_n47_p16009_Marino
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	paper:paper_00404020_v53_n47_p16009_Marino
record_format	dspace
spelling	paper:paper_00404020_v53_n47_p16009_Marino2023-06-08T15:04:12Z Reactions of per-O-benzoyl-β-D-galf isothiocyanate, a chiral resolving agent Marino, María Carla Varela, Oscar José Muchnik de Lederkremer, Rosa María isothiocyanic acid derivative tetra o benzoyl beta galactofuranosylisothiocyanate unclassified drug antifungal activity antimicrobial activity article drug conformation priority journal stereochemistry structure activity relation Tetra-O-benzoyl-β-D-galactofuranosyl isothiocyanate (1) was readily prepared (90% yield) from per-O-benzoyl-D-galactofuranose, via the glycosyl bromide. Reaction of 1 with alcohols, amines and amino acids afforded a variety of glycosylthiourethanes and glycosylthioureides. The isothiocyanate 1 showed to be useful as a chiral resolving agent. The resolution of recemic primary and secondary mines and aminoalcohols was readily accomplished, in analytical and preparative scale, by condensation of such compounds with 1. Fil:Marino, C. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Varela, O. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:De Lederkremer, R.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 1997 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00404020_v53_n47_p16009_Marino http://hdl.handle.net/20.500.12110/paper_00404020_v53_n47_p16009_Marino
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	isothiocyanic acid derivative tetra o benzoyl beta galactofuranosylisothiocyanate unclassified drug antifungal activity antimicrobial activity article drug conformation priority journal stereochemistry structure activity relation
spellingShingle	isothiocyanic acid derivative tetra o benzoyl beta galactofuranosylisothiocyanate unclassified drug antifungal activity antimicrobial activity article drug conformation priority journal stereochemistry structure activity relation Marino, María Carla Varela, Oscar José Muchnik de Lederkremer, Rosa María Reactions of per-O-benzoyl-β-D-galf isothiocyanate, a chiral resolving agent
topic_facet	isothiocyanic acid derivative tetra o benzoyl beta galactofuranosylisothiocyanate unclassified drug antifungal activity antimicrobial activity article drug conformation priority journal stereochemistry structure activity relation
description	Tetra-O-benzoyl-β-D-galactofuranosyl isothiocyanate (1) was readily prepared (90% yield) from per-O-benzoyl-D-galactofuranose, via the glycosyl bromide. Reaction of 1 with alcohols, amines and amino acids afforded a variety of glycosylthiourethanes and glycosylthioureides. The isothiocyanate 1 showed to be useful as a chiral resolving agent. The resolution of recemic primary and secondary mines and aminoalcohols was readily accomplished, in analytical and preparative scale, by condensation of such compounds with 1.
author	Marino, María Carla Varela, Oscar José Muchnik de Lederkremer, Rosa María
author_facet	Marino, María Carla Varela, Oscar José Muchnik de Lederkremer, Rosa María
author_sort	Marino, María Carla
title	Reactions of per-O-benzoyl-β-D-galf isothiocyanate, a chiral resolving agent
title_short	Reactions of per-O-benzoyl-β-D-galf isothiocyanate, a chiral resolving agent
title_full	Reactions of per-O-benzoyl-β-D-galf isothiocyanate, a chiral resolving agent
title_fullStr	Reactions of per-O-benzoyl-β-D-galf isothiocyanate, a chiral resolving agent
title_full_unstemmed	Reactions of per-O-benzoyl-β-D-galf isothiocyanate, a chiral resolving agent
title_sort	reactions of per-o-benzoyl-β-d-galf isothiocyanate, a chiral resolving agent
publishDate	1997
url	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00404020_v53_n47_p16009_Marino http://hdl.handle.net/20.500.12110/paper_00404020_v53_n47_p16009_Marino
work_keys_str_mv	AT marinomariacarla reactionsofperobenzoylbdgalfisothiocyanateachiralresolvingagent AT varelaoscarjose reactionsofperobenzoylbdgalfisothiocyanateachiralresolvingagent AT muchnikdelederkremerrosamaria reactionsofperobenzoylbdgalfisothiocyanateachiralresolvingagent
_version_	1768542496703381504

Reactions of per-O-benzoyl-β-D-galf isothiocyanate, a chiral resolving agent

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