Agarofuran sesquiterpenes from Schaefferia argentinensis
Sixteen dihydro-β-agarofuran sesquiterpenes were isolated from the aerial parts of Schaefferia argentinensis Speg. Their structures were determined by a combination of 1D and 2D NMR and MS techniques. The in vitro antiproliferative activity of the major sesquiterpenes was examined in T47D, MCF7, and...
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Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00319422_v94_n_p260_Garcia http://hdl.handle.net/20.500.12110/paper_00319422_v94_n_p260_Garcia |
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paper:paper_00319422_v94_n_p260_Garcia2023-06-08T14:59:43Z Agarofuran sesquiterpenes from Schaefferia argentinensis Antiproliferative activity Celastraceae Dihydro-β-agarofuran sesquiterpene Phytochemistry Schaefferia argentinensis Celastraceae Schaefferia (angiosperm) antineoplastic agent dihydroagarofuran sesquiterpene antiproliferative activity article Celastraceae cell proliferation cell strain MCF 7 cell survival chemical structure chemistry Dihydro-β-agarofuran sesquiterpene drug effect human isolation and purification mass spectrometry methodology nuclear magnetic resonance spectroscopy phytochemistry plant Schaefferia argentinensis tumor cell line Antiproliferative activity Celastraceae Dihydro-β-agarofuran sesquiterpene Phytochemistry Schaefferia argentinensis Antineoplastic Agents, Phytogenic Celastraceae Cell Line, Tumor Cell Proliferation Cell Survival Humans Magnetic Resonance Spectroscopy Mass Spectrometry MCF-7 Cells Molecular Structure Plant Components, Aerial Sesquiterpenes Sixteen dihydro-β-agarofuran sesquiterpenes were isolated from the aerial parts of Schaefferia argentinensis Speg. Their structures were determined by a combination of 1D and 2D NMR and MS techniques. The in vitro antiproliferative activity of the major sesquiterpenes was examined in T47D, MCF7, and MDA-MB231 human cancer cell lines, but was found to be marginal. © 2013 Elsevier Ltd. All rights reserved. 2013 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00319422_v94_n_p260_Garcia http://hdl.handle.net/20.500.12110/paper_00319422_v94_n_p260_Garcia |
institution |
Universidad de Buenos Aires |
institution_str |
I-28 |
repository_str |
R-134 |
collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
topic |
Antiproliferative activity Celastraceae Dihydro-β-agarofuran sesquiterpene Phytochemistry Schaefferia argentinensis Celastraceae Schaefferia (angiosperm) antineoplastic agent dihydroagarofuran sesquiterpene antiproliferative activity article Celastraceae cell proliferation cell strain MCF 7 cell survival chemical structure chemistry Dihydro-β-agarofuran sesquiterpene drug effect human isolation and purification mass spectrometry methodology nuclear magnetic resonance spectroscopy phytochemistry plant Schaefferia argentinensis tumor cell line Antiproliferative activity Celastraceae Dihydro-β-agarofuran sesquiterpene Phytochemistry Schaefferia argentinensis Antineoplastic Agents, Phytogenic Celastraceae Cell Line, Tumor Cell Proliferation Cell Survival Humans Magnetic Resonance Spectroscopy Mass Spectrometry MCF-7 Cells Molecular Structure Plant Components, Aerial Sesquiterpenes |
spellingShingle |
Antiproliferative activity Celastraceae Dihydro-β-agarofuran sesquiterpene Phytochemistry Schaefferia argentinensis Celastraceae Schaefferia (angiosperm) antineoplastic agent dihydroagarofuran sesquiterpene antiproliferative activity article Celastraceae cell proliferation cell strain MCF 7 cell survival chemical structure chemistry Dihydro-β-agarofuran sesquiterpene drug effect human isolation and purification mass spectrometry methodology nuclear magnetic resonance spectroscopy phytochemistry plant Schaefferia argentinensis tumor cell line Antiproliferative activity Celastraceae Dihydro-β-agarofuran sesquiterpene Phytochemistry Schaefferia argentinensis Antineoplastic Agents, Phytogenic Celastraceae Cell Line, Tumor Cell Proliferation Cell Survival Humans Magnetic Resonance Spectroscopy Mass Spectrometry MCF-7 Cells Molecular Structure Plant Components, Aerial Sesquiterpenes Agarofuran sesquiterpenes from Schaefferia argentinensis |
topic_facet |
Antiproliferative activity Celastraceae Dihydro-β-agarofuran sesquiterpene Phytochemistry Schaefferia argentinensis Celastraceae Schaefferia (angiosperm) antineoplastic agent dihydroagarofuran sesquiterpene antiproliferative activity article Celastraceae cell proliferation cell strain MCF 7 cell survival chemical structure chemistry Dihydro-β-agarofuran sesquiterpene drug effect human isolation and purification mass spectrometry methodology nuclear magnetic resonance spectroscopy phytochemistry plant Schaefferia argentinensis tumor cell line Antiproliferative activity Celastraceae Dihydro-β-agarofuran sesquiterpene Phytochemistry Schaefferia argentinensis Antineoplastic Agents, Phytogenic Celastraceae Cell Line, Tumor Cell Proliferation Cell Survival Humans Magnetic Resonance Spectroscopy Mass Spectrometry MCF-7 Cells Molecular Structure Plant Components, Aerial Sesquiterpenes |
description |
Sixteen dihydro-β-agarofuran sesquiterpenes were isolated from the aerial parts of Schaefferia argentinensis Speg. Their structures were determined by a combination of 1D and 2D NMR and MS techniques. The in vitro antiproliferative activity of the major sesquiterpenes was examined in T47D, MCF7, and MDA-MB231 human cancer cell lines, but was found to be marginal. © 2013 Elsevier Ltd. All rights reserved. |
title |
Agarofuran sesquiterpenes from Schaefferia argentinensis |
title_short |
Agarofuran sesquiterpenes from Schaefferia argentinensis |
title_full |
Agarofuran sesquiterpenes from Schaefferia argentinensis |
title_fullStr |
Agarofuran sesquiterpenes from Schaefferia argentinensis |
title_full_unstemmed |
Agarofuran sesquiterpenes from Schaefferia argentinensis |
title_sort |
agarofuran sesquiterpenes from schaefferia argentinensis |
publishDate |
2013 |
url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00319422_v94_n_p260_Garcia http://hdl.handle.net/20.500.12110/paper_00319422_v94_n_p260_Garcia |
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1768545821456859136 |