Photochemical and thermal stability of some dihydroxyacetophenones used as UV-MALDI-MS matrices
2,4-, 2,5-, 2,6- and 3,5-dihydroxyacetophenone (DHA) used as matrices in matrix-assisted ultraviolet laser desorption/ionization mass spectrometry (UV-MALDI-MS) were studied by steady-state and transient absorption spectroscopy, together with DFT calculations at the B3LYP level of theory. All compou...
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2013
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| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00318655_v89_n6_p1368_Tarzi http://hdl.handle.net/20.500.12110/paper_00318655_v89_n6_p1368_Tarzi |
| Aporte de: |
| id |
paper:paper_00318655_v89_n6_p1368_Tarzi |
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| record_format |
dspace |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
2,6-dihydroxyacetophenone acetophenone derivative chemistry mass spectrometry photochemistry procedures ultraviolet spectrophotometry Acetophenones Photochemistry Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Spectrophotometry, Ultraviolet |
| spellingShingle |
2,6-dihydroxyacetophenone acetophenone derivative chemistry mass spectrometry photochemistry procedures ultraviolet spectrophotometry Acetophenones Photochemistry Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Spectrophotometry, Ultraviolet Photochemical and thermal stability of some dihydroxyacetophenones used as UV-MALDI-MS matrices |
| topic_facet |
2,6-dihydroxyacetophenone acetophenone derivative chemistry mass spectrometry photochemistry procedures ultraviolet spectrophotometry Acetophenones Photochemistry Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Spectrophotometry, Ultraviolet |
| description |
2,4-, 2,5-, 2,6- and 3,5-dihydroxyacetophenone (DHA) used as matrices in matrix-assisted ultraviolet laser desorption/ionization mass spectrometry (UV-MALDI-MS) were studied by steady-state and transient absorption spectroscopy, together with DFT calculations at the B3LYP level of theory. All compounds have low fluorescence quantum yields, possibly due to an efficient excited-state intramolecular proton transfer (ESIPT). Laser flash photolysis (LFP) results showed that, only for 2,4-DHA, a phototautomer could be detected at λ = 400 nm. Their photochemical stability in solution at different wavelengths and conditions was analyzed by UV-Vis and 1H nuclear magnetic resonance spectroscopy (1H-NMR), together with thin layer chromatography and ultraviolet laser desorption/ionization mass spectrometry (UV-LDI-MS). Only 3,5-DHA showed decomposition when irradiated, probably because phototautomerization is not possible. Thermal stability studies of these compounds in solid state were also conducted. © 2013 The American Society of Photobiology. |
| title |
Photochemical and thermal stability of some dihydroxyacetophenones used as UV-MALDI-MS matrices |
| title_short |
Photochemical and thermal stability of some dihydroxyacetophenones used as UV-MALDI-MS matrices |
| title_full |
Photochemical and thermal stability of some dihydroxyacetophenones used as UV-MALDI-MS matrices |
| title_fullStr |
Photochemical and thermal stability of some dihydroxyacetophenones used as UV-MALDI-MS matrices |
| title_full_unstemmed |
Photochemical and thermal stability of some dihydroxyacetophenones used as UV-MALDI-MS matrices |
| title_sort |
photochemical and thermal stability of some dihydroxyacetophenones used as uv-maldi-ms matrices |
| publishDate |
2013 |
| url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00318655_v89_n6_p1368_Tarzi http://hdl.handle.net/20.500.12110/paper_00318655_v89_n6_p1368_Tarzi |
| bdutipo_str |
Repositorios |
| _version_ |
1764820560849666048 |