Utilization of extracellular information before ligand-receptor binding reaches equilibrium expands and shifts the input dynamic range
Cell signaling systems sense and respond to ligands that bind cell surface receptors. These systems often respond to changes in the concentration of extracellular ligand more rapidly than the ligand equilibrates with its receptor. We demonstrate, by modeling and experiment, a general "systems l...
Guardado en:
| Autores principales: | Ventura, Alejandra C., Bush, Alan, Chernomoretz, Ariel, Colman Lerner, Alejandro Ariel |
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| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00278424_v111_n37_pE3860_Ventura http://hdl.handle.net/20.500.12110/paper_00278424_v111_n37_pE3860_Ventura |
| Aporte de: |
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