Ruv and recG genes and the induced precise excision of Tn10 in Escherichia coli

Induction of precise excision of Tn10 by UV or mitomycin C (MMC) is dependent on the expression of the SOS system. Ruv mutants of Escherichia coli, which are defective in DNA repair and recombination, showed diminished frequencies of both spontaneous and UV- or MMC-induced excision of Tn10 inserted...

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Autores principales:	Nagel de Zwaig, Rosa, Rosen, Eva María
Publicado:	1994
Materias:	MMC induction RecGamutants Ruv mutants SOS genes Tn10 precise excision UV induction mitomycin c article controlled study dna excision escherichia coli gene mutant nonhuman priority journal transposon ultraviolet radiation Bacterial Proteins DNA Transposable Elements Escherichia coli Mitomycin Mutagens Mutation Support, Non-U.S. Gov't Ultraviolet Rays
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00275107_v311_n1_p103_Nagel http://hdl.handle.net/20.500.12110/paper_00275107_v311_n1_p103_Nagel
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	paper:paper_00275107_v311_n1_p103_Nagel
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spelling	paper:paper_00275107_v311_n1_p103_Nagel2023-06-08T14:54:09Z Ruv and recG genes and the induced precise excision of Tn10 in Escherichia coli Nagel de Zwaig, Rosa Rosen, Eva María MMC induction RecGamutants Ruv mutants SOS genes Tn10 precise excision UV induction mitomycin c article controlled study dna excision escherichia coli gene mutant nonhuman priority journal transposon ultraviolet radiation Bacterial Proteins DNA Transposable Elements Escherichia coli Mitomycin Mutagens Mutation Support, Non-U.S. Gov't Ultraviolet Rays Escherichia coli Induction of precise excision of Tn10 by UV or mitomycin C (MMC) is dependent on the expression of the SOS system. Ruv mutants of Escherichia coli, which are defective in DNA repair and recombination, showed diminished frequencies of both spontaneous and UV- or MMC-induced excision of Tn10 inserted in gal. RecG mutants, which are also defective in DNA repair and recombination, showed decreased induction of Tn10 excision with MMC, but not after UV treatment. A recG ruv double mutant showed a greater decrease in induction of excision with MMC than either single mutant. One can speculate that the Ruv proteins, which are known to be involved in the resolution of Holliday junctions, might also be involved in the resolution of putative intermediates generated during the precise excision of Tn10. RecG protein, whose function partially overlaps those of Ruv proteins, might also have some role in this process. © 1994. Fil:Nagel, R. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Rosen, E. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 1994 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00275107_v311_n1_p103_Nagel http://hdl.handle.net/20.500.12110/paper_00275107_v311_n1_p103_Nagel
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	MMC induction RecGamutants Ruv mutants SOS genes Tn10 precise excision UV induction mitomycin c article controlled study dna excision escherichia coli gene mutant nonhuman priority journal transposon ultraviolet radiation Bacterial Proteins DNA Transposable Elements Escherichia coli Mitomycin Mutagens Mutation Support, Non-U.S. Gov't Ultraviolet Rays Escherichia coli
spellingShingle	MMC induction RecGamutants Ruv mutants SOS genes Tn10 precise excision UV induction mitomycin c article controlled study dna excision escherichia coli gene mutant nonhuman priority journal transposon ultraviolet radiation Bacterial Proteins DNA Transposable Elements Escherichia coli Mitomycin Mutagens Mutation Support, Non-U.S. Gov't Ultraviolet Rays Escherichia coli Nagel de Zwaig, Rosa Rosen, Eva María Ruv and recG genes and the induced precise excision of Tn10 in Escherichia coli
topic_facet	MMC induction RecGamutants Ruv mutants SOS genes Tn10 precise excision UV induction mitomycin c article controlled study dna excision escherichia coli gene mutant nonhuman priority journal transposon ultraviolet radiation Bacterial Proteins DNA Transposable Elements Escherichia coli Mitomycin Mutagens Mutation Support, Non-U.S. Gov't Ultraviolet Rays Escherichia coli
description	Induction of precise excision of Tn10 by UV or mitomycin C (MMC) is dependent on the expression of the SOS system. Ruv mutants of Escherichia coli, which are defective in DNA repair and recombination, showed diminished frequencies of both spontaneous and UV- or MMC-induced excision of Tn10 inserted in gal. RecG mutants, which are also defective in DNA repair and recombination, showed decreased induction of Tn10 excision with MMC, but not after UV treatment. A recG ruv double mutant showed a greater decrease in induction of excision with MMC than either single mutant. One can speculate that the Ruv proteins, which are known to be involved in the resolution of Holliday junctions, might also be involved in the resolution of putative intermediates generated during the precise excision of Tn10. RecG protein, whose function partially overlaps those of Ruv proteins, might also have some role in this process. © 1994.
author	Nagel de Zwaig, Rosa Rosen, Eva María
author_facet	Nagel de Zwaig, Rosa Rosen, Eva María
author_sort	Nagel de Zwaig, Rosa
title	Ruv and recG genes and the induced precise excision of Tn10 in Escherichia coli
title_short	Ruv and recG genes and the induced precise excision of Tn10 in Escherichia coli
title_full	Ruv and recG genes and the induced precise excision of Tn10 in Escherichia coli
title_fullStr	Ruv and recG genes and the induced precise excision of Tn10 in Escherichia coli
title_full_unstemmed	Ruv and recG genes and the induced precise excision of Tn10 in Escherichia coli
title_sort	ruv and recg genes and the induced precise excision of tn10 in escherichia coli
publishDate	1994
url	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00275107_v311_n1_p103_Nagel http://hdl.handle.net/20.500.12110/paper_00275107_v311_n1_p103_Nagel
work_keys_str_mv	AT nageldezwaigrosa ruvandrecggenesandtheinducedpreciseexcisionoftn10inescherichiacoli AT rosenevamaria ruvandrecggenesandtheinducedpreciseexcisionoftn10inescherichiacoli
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Ruv and recG genes and the induced precise excision of Tn10 in Escherichia coli

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