Synthesis and isolation of nitro-β-carbolines obtained by nitration of commercial β-carboline alkaloids
Nitration of commercial full aromatic β-carboline alkaloids nor-harmane (1), harmane (2), harmine (3), harmol (4), and the 7-acetylated derivative of harmol (5) is described. Advantages and disadvantages of different nitration reagents which involve acidic conditions (HNO3/H+) and neutral conditions...
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2001
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| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0022152X_v38_n5_p1071_Ponce http://hdl.handle.net/20.500.12110/paper_0022152X_v38_n5_p1071_Ponce |
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paper:paper_0022152X_v38_n5_p1071_Ponce2023-06-08T14:46:47Z Synthesis and isolation of nitro-β-carbolines obtained by nitration of commercial β-carboline alkaloids Ponce, María Alejandra Erra Balsells, Rosa ammonium nitrate beta carboline carboline derivative carbon 13 copper derivative harman harmine harmol harmol derivative unclassified drug article drug isolation drug synthesis light absorption nitration nuclear magnetic resonance spectroscopy proton nuclear magnetic resonance reaction analysis ultraviolet spectroscopy Nitration of commercial full aromatic β-carboline alkaloids nor-harmane (1), harmane (2), harmine (3), harmol (4), and the 7-acetylated derivative of harmol (5) is described. Advantages and disadvantages of different nitration reagents which involve acidic conditions (HNO3/H+) and neutral conditions (Cu(NO3)2; ceric ammonium nitrate) are discussed. A complete 1H and 13C-nmr characterization including ms and also uv absorption spectra in neutral and acid media is presented. A detailed ei-ms and ld-tof-ms study is enclosed because the nitro-β-carbolines constitute a new family of β-carboline-like chromophores with potential use as matrix in uv-maldi-tof-ms. Fil:Ponce, M.A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Erra-Balsells, R. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 2001 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0022152X_v38_n5_p1071_Ponce http://hdl.handle.net/20.500.12110/paper_0022152X_v38_n5_p1071_Ponce |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
ammonium nitrate beta carboline carboline derivative carbon 13 copper derivative harman harmine harmol harmol derivative unclassified drug article drug isolation drug synthesis light absorption nitration nuclear magnetic resonance spectroscopy proton nuclear magnetic resonance reaction analysis ultraviolet spectroscopy |
| spellingShingle |
ammonium nitrate beta carboline carboline derivative carbon 13 copper derivative harman harmine harmol harmol derivative unclassified drug article drug isolation drug synthesis light absorption nitration nuclear magnetic resonance spectroscopy proton nuclear magnetic resonance reaction analysis ultraviolet spectroscopy Ponce, María Alejandra Erra Balsells, Rosa Synthesis and isolation of nitro-β-carbolines obtained by nitration of commercial β-carboline alkaloids |
| topic_facet |
ammonium nitrate beta carboline carboline derivative carbon 13 copper derivative harman harmine harmol harmol derivative unclassified drug article drug isolation drug synthesis light absorption nitration nuclear magnetic resonance spectroscopy proton nuclear magnetic resonance reaction analysis ultraviolet spectroscopy |
| description |
Nitration of commercial full aromatic β-carboline alkaloids nor-harmane (1), harmane (2), harmine (3), harmol (4), and the 7-acetylated derivative of harmol (5) is described. Advantages and disadvantages of different nitration reagents which involve acidic conditions (HNO3/H+) and neutral conditions (Cu(NO3)2; ceric ammonium nitrate) are discussed. A complete 1H and 13C-nmr characterization including ms and also uv absorption spectra in neutral and acid media is presented. A detailed ei-ms and ld-tof-ms study is enclosed because the nitro-β-carbolines constitute a new family of β-carboline-like chromophores with potential use as matrix in uv-maldi-tof-ms. |
| author |
Ponce, María Alejandra Erra Balsells, Rosa |
| author_facet |
Ponce, María Alejandra Erra Balsells, Rosa |
| author_sort |
Ponce, María Alejandra |
| title |
Synthesis and isolation of nitro-β-carbolines obtained by nitration of commercial β-carboline alkaloids |
| title_short |
Synthesis and isolation of nitro-β-carbolines obtained by nitration of commercial β-carboline alkaloids |
| title_full |
Synthesis and isolation of nitro-β-carbolines obtained by nitration of commercial β-carboline alkaloids |
| title_fullStr |
Synthesis and isolation of nitro-β-carbolines obtained by nitration of commercial β-carboline alkaloids |
| title_full_unstemmed |
Synthesis and isolation of nitro-β-carbolines obtained by nitration of commercial β-carboline alkaloids |
| title_sort |
synthesis and isolation of nitro-β-carbolines obtained by nitration of commercial β-carboline alkaloids |
| publishDate |
2001 |
| url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0022152X_v38_n5_p1071_Ponce http://hdl.handle.net/20.500.12110/paper_0022152X_v38_n5_p1071_Ponce |
| work_keys_str_mv |
AT poncemariaalejandra synthesisandisolationofnitrobcarbolinesobtainedbynitrationofcommercialbcarbolinealkaloids AT errabalsellsrosa synthesisandisolationofnitrobcarbolinesobtainedbynitrationofcommercialbcarbolinealkaloids |
| _version_ |
1768541971696058368 |